Cases reported "Burning Mouth Syndrome"

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1/4. burning mouth syndrome due to cadmium in a denture wearer.

    We report the case of a female denture wearer who was referred to our service due to burning of the lips and tongue but with no visible oral lesions. Her biochemical data, complete blood cell count, sedimentation rate, thyroid and sex hormones were normal. tongue culture was negative. patch tests, performed with a panel of 20 potential denture allergens, gave positive results ( ) only to a 2% petrolatum cadmium sulfate, which was present in the denture. Removal of the denture led to the clearing up of oral symptoms in 3 days. In light of these findings, carrying out patch tests with the allergens related to denture materials should be considered in these cases.
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ranking = 1
keywords = patch test, patch
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2/4. Recovery from mercury-induced burning mouth syndrome due to mercury allergy.

    We report a case in which burning mouth syndrome (BMS) was associated with a strong allergy to mercury. The aim of this case history is to strengthen knowledge of the relationship among allergy to mercury, systemic allergic contact dermatitis, and hypersensitivity of the oral mucosa. We performed series of standard and dental patch tests for screening for contact allergy to dental materials, in accordance with International Contact dermatitis research Group guidelines. Positive extreme allergic reactions to mercury ( ) and amalgam ( ) were seen at the patch site and caused a flare-up of the systemic erythematous reaction. Full recovery from BMS and complete remission of systemic dermatitis were achieved after the mercury tooth filling was removed. mercury is thought to be an allergen implicated in BMS as well as in the systemic reactivation of allergic contact dermatitis. Patch testing with dental series seems to have greater sensitivity and relevance in BMS patients.
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ranking = 1.0041320832543
keywords = patch test, patch
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3/4. Peanut sensitivity as a cause of burning mouth.

    A patient with a history of a burning tongue together with discomfort of the labial and buccal mucosae was given an elimination diet and skin patch tests to determine the allergen in her diet. The patient was identified as being intolerant of an aqueous peanut extract. Three allergens in peanut butter were identified, the one with greatest reactivity being a heat-stable, water-soluble, nonglycosylated protein with a molecular weight in excess of 10 kD. Modification of her diet has resulted in resolution of the oral problem.
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ranking = 1
keywords = patch test, patch
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4/4. skin sensitivity to denture base materials in the burning mouth syndrome.

    The significance of sensitizing compounds in the denture base for the etiology of the burning mouth syndrome (BMS) has been studied in 53 denture-wearing persons, seven males and 46 females. Epicutaneous patch tests were performed with standard concentrations of benzoyl peroxide, dibutylphthalate, dimethyl-p-toluidine, formaldehyde, hydroquinone, methylmethacrylate, p-phenylendiamine and with cadmium sulfate, potassium dichromate, cobalt chloride and nickel sulfate. Furthermore, patch testing was performed with filings from the denture mixed with the patient's own saliva. In cases with an inflamed oral mucosa, the presence of hyphae of candida albicans was assessed by a smear technique. Positive skin reactions were observed in 15 persons to dimethyl-p-toluidine, hydroquinone, formaldehyde, methylmethacrylate, p-phenylendiamine, potassium dichromate, cobalt chloride and nickel sulfate, including three cases with reactions to filings from their dentures, and one patient who after subsequent testing showed skin sensitivity to balsam of peru. In 12 cases an etiological connection could be traced between the oral symptoms and the denture base, indicating that contact sensitivity to base materials or to allergens and microbial antigens on the denture plate plays a greater role in the pathogenesis of BMS in edentulous persons than previously suggested.
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ranking = 2
keywords = patch test, patch
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