Cases reported "Chorioamnionitis"

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1/2. Fusobacterium: anaerobic occult amnionitis and premature labor.

    Fusobacterium species are well established pathogens. Before the advent of effective anaerobic antimicrobial therapy, they were associated with prolonged, often fatal courses. Previously, fusobacterium had not been identified as a common perinatal pathogen. Three cases of occult amnionitis due to Fusobacterium are presented. review of five series of occult amnionitis revealed 23 cases. In seven (30.4%), Fusobacterium was isolated. In 14 (60.8%), an anaerobic species was isolated. The average gestational age of patients from whom anaerobes were grown was 29.0 weeks. Of those that grew no anaerobes, the average gestational age was 32.3 weeks (P less than .05). The overall rate of maternal febrile morbidity was 35%. Fusobacterium accounted for 50% of the febrile cases while accounting for only 30.4% of the total cases.
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ranking = 1
keywords = fusobacterium
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2/2. Orogenital contact: a cause of chorioamnionitis?

    BACKGROUND: fusobacterium nucleatum and capnocytophaga species are common oral pathogens and infrequent causes of systemic infection in patients with compromised immunity or disrupted mucosal integrity. The isolation of both organisms from a clinical specimen suggests an oral source of infection. CASE: A 23-year-old black woman was admitted at 24 weeks' gestation in preterm labor. She subsequently developed signs of clinical chorioamnionitis, including fever, fetal tachycardia, and uterine tenderness. Bacteriologic studies of the amniotic fluid and subchorionic placental cultures yielded F nucleatum and capnocytophaga species. On review of the patient's history, a temporal relation was noted between orogenital contact and the onset of clinical infection. Thorough evaluation of the patient, including dental examination, did not reveal an obvious source of infection. However, significant periodontal disease was identified in her partner. CONCLUSION: The concomitant finding of these two organisms in the patient's amniotic fluid and a history of periodontal disease in her partner suggests that chorioamnionitis may have been due to an ascending infection after orogenital contact.
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ranking = 5.1261812610831
keywords = nucleatum
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