Cases reported "Coccidioidomycosis"

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1/4. Coccidioidal meningitis presenting as memory loss.

    PURPOSE: This case study is designed to help the nurse practitioner recognize atypical symptoms of coccidioidal meningitis, particularly in high-risk groups that require further diagnostic treatment. DATA SOURCES: Selected research, clinical articles, and case studies. CONCLUSIONS: Coccidioidal meningitis is a potentially lethal infection unless recognized and treated. Unlike other infectious meningitides that present with more acute meningeal symptoms, disseminated coccidioidomycosis can present insidiously. When it presents as cognitive dysfunction, it may be mistaken for early dementia and if undiagnosed can result in death. While it is an infectious disease that is endemic to a small number of southwestern states, these areas see a high volume of tourists who can unwittingly become infected. knowledge of this infectious disease and the many ways it can imitate other diseases is critical to its early recognition and treatment. IMPLICATIONS FOR PRACTICE: Failure to recognize this reemerging, endemic fungal infection in high-risk groups can result in death.
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2/4. Cold subcutaneous abscesses.

    Cold abscesses are defined as having no associated erythema, heat, or tenderness. They may be present in immunodeficiency disorders, deep mycoses, and other infectious diseases. As there is a dearth information on this subject in the dermatology, surgery, and infectious disease literature, we present a case of cold abscesses secondary to coccidioidomycosis and discuss the possible role of humoral immunity, cell-mediated immunity, prostaglandins, T cells, and other mediators in cold abscess pathogenesis. In addition, therapeutic guidelines for abscesses are reviewed.
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3/4. Rapid diagnosis of coccidioidomycosis with a dna probe to ribosomal rna.

    BACKGROUND: Although nucleic acid probe hybridization assays were previously exclusively used as a tool in the research setting, such assays have recently become commercially available for the detection of a variety of infectious microorganisms. OBSERVATIONS: We used a commercially available dna hybridization probe test that targets organism-specific ribosomal rna sequences to rapidly diagnose a patient with disseminated coccidioidomycosis. The natural amplification inherent to such dna:rna probe systems obviates the need for electrophoretic separation and amplification steps, which are often required in more traditional dna:dna probe assays. With this probe, culture confirmation was obtained within 48 hours after the clinical specimens were received. CONCLUSION: Rapid dna hybridization probe techniques have wide application in infectious diseases, especially those characterized by slow culture growth of pathogens such as deep fungi and atypical mycobacteria.
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keywords = infectious disease
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4/4. Pulmonary coccidioidomycosis in kentucky.

    coccidioidomycosis is a highly infectious disease caused by the dimorphic fungus, coccidioides immitis that is endemic to the arid and semiarid regions of the southwestern united states, mexico, central america, and south america. The majority of infections from C immitis are asymptomatic; however, approximately 40% of infected individuals present with symptoms ranging from a mild flu-like respiratory infection to acute pneumonia that may lead to chronic progressive pulmonary infection or occasionally disseminated disease. Due to the mobility of the population, increasing numbers of cases are being recognized outside endemic areas. We report five patients with coccidioidomycosis diagnosed at the University of kentucky Medical Center during the period from 1984 to 1993 in order to illustrate the clinical and radiographic spectrum of findings that may be encountered with the disease. In a patient with unexplained pulmonary symptoms, a history of recent travel to or immigration from an endemic area may be an early clue to the diagnosis of coccidioidomycosis.
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