Filter by keywords:



Filtering documents. Please wait...

1/3. severe acute respiratory syndrome (SARS) in singapore: clinical features of index patient and initial contacts.

    severe acute respiratory syndrome (SARS) is an emerging viral infectious disease. One of the largest outbreaks of SARS to date began in singapore in March 2003. We describe the clinical, laboratory, and radiologic features of the index patient and the patient's initial contacts affected with probable SARS.
- - - - - - - - - -
ranking = 1
keywords = infectious disease
(Clic here for more details about this article)

2/3. Reemerging leptospirosis, california.

    leptospirosis is a reemerging infectious disease in california. leptospirosis is the most widespread zoonosis throughout the world, though it is infrequently diagnosed in the continental united states. From 1982 to 2001, most reported california cases occurred in previously healthy young adult white men after recreational exposures to contaminated freshwater. We report five recent cases of human leptospirosis acquired in california, including the first documented common-source outbreak of human leptospirosis acquired in this state, and describe the subsequent environmental investigation. Salient features in the california cases include high fever with uniform renal impairment and mild hepatitis. Because leptospirosis can progress rapidly if untreated, this reemerging infection deserves consideration in febrile patients with a history of recreational freshwater exposure, even in states with a low reported incidence of infection.
- - - - - - - - - -
ranking = 1
keywords = infectious disease
(Clic here for more details about this article)

3/3. saccharomyces cerevisiae fungemia: an emerging infectious disease.

    BACKGROUND: saccharomyces cerevisiae is well known in the baking and brewing industry and is also used as a probiotic in humans. However, it is a very uncommon cause of infection in humans. methods: During the period of 15-30 April 2003, we found 3 patients with S. cerevisiae fungemia in an intensive care unit (ICU). An epidemiological study was performed, and the medical records for all patients who were in the unit during the second half of April were assessed. RESULTS: The only identified risk factor for S. cerevisiae infection was treatment with a probiotic containing Saccharomyces boulardii (Ultralevura; Bristol-Myers Squibb). This probiotic is used in europe for the treatment and prevention of clostridium difficile-associated diarrhea. The 3 patients received the product via nasograstric tube for a mean duration of 8.5 days before the culture result was positive, whereas only 2 of 41 control subjects had received it. Surveillance cultures for the control patients admitted at the same time did not reveal any carriers of the yeast. Strains from the probiotic capsules and the clinical isolates were identified as S. cerevisiae, with identical dna fingerprinting. Discontinuation of use of the product in the unit stopped the outbreak of infection. A review of the literature identified another 57 cases of S. cerevisiae fungemia. overall, 60% of these patients were in the ICU, and 71% were receiving enteral or parenteral nutrition. Use of probiotics was detected in 26 patients, and 17 patients died. CONCLUSIONS: Use of S. cerevisiae probiotics should be carefully reassessed, particularly in immunosuppressed or critically ill patients.
- - - - - - - - - -
ranking = 4
keywords = infectious disease
(Clic here for more details about this article)


Leave a message about 'Communicable Diseases, Emerging'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.