Cases reported "Conjunctival Diseases"

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1/6. Neurotrophic corneal endothelial failure complicating acute horner syndrome.

    PURPOSE: The authors report the clinical findings of a unique case of rapid corneal endothelial decompensation in association with acute horner syndrome. STUDY DESIGN: Case report and literature review. methods: The authors followed a 38-year-old woman who developed horner syndrome after right jugular vein catheterization during cardiac valvular surgery. Shortly after the operation, horner syndrome accompanied by conjunctival hyperemia and stromal corneal edema developed in the right eye. Over the course of 4 months, the eye became painful, the corneal endothelial cell count dropped precipitously, and the stromal edema worsened, causing a difference of 100 microm in central corneal thickness compared to the unaffected eye. Deep stromal vascularization started at the limbus, resembling interstitial keratitis. RESULTS: A 3-week course of topical steroid treatment resulted in a dramatic improvement in the stromal corneal edema and regression of the deep stromal vascularization. Ocular and right hemicranial pain subsided shortly thereafter. CONCLUSION: The authors hypothesize that corneal endothelial failure in this unique case may have resulted from traumatic sympathectomy. According to experimental evidence in the reviewed ophthalmologic literature, sympathetic innervation may have a neurotrophic role in the cornea. Corneal pathology similar to the authors' case has been described in hemifacial atrophy (Parry-Robson syndrome), a disorder that is assumed to result from sympathetic denervation and that can be produced in animals by cervical sympathectomy. The authors therefore hypothesize that sympathetic denervation of the cornea may rarely cause endothelial decompensation and corneal edema. To the authors' knowledge, this is the first reported case of corneal endothelial failure in horner syndrome.
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2/6. Case report: ophthalmomyiasis externa in Dallas County, texas.

    Ophthalmomyiasis externa is an uncommon condition in north america. If not recognized and managed accordingly, it can be complicated by the potentially fatal condition ophthalmomyiasis interna. Ophthalmomyiasis externa is mainly caused by the sheep bot fly Oestrus ovis; thus, it is more common in farming communities. We report a case of ophthalmomyiasis externa in a young woman from Dallas County, texas, who had no known history of contact with farm animals.
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3/6. Topical application of 5-fluorouracil in premalignant lesions of cornea, conjunctiva and eyelid.

    Local application of 5-fluorouracil was practised on 5 patients. In 3 patients with multiple premalignant oculo-cutaneous lesions, two of whom had also premalignant epibulbar lesions, local 5% 5-Fu cream and/or 1% 5-Fu eyedrops were applied. In 2 other patients who had only premalignant lesions on the cornea and conjunctiva, 1% 5-Fu eyedrops were used only. In animal experiments 1% 5-Fu was not found to cause any damage to normal corneal and conjunctival epithelium. The frequency of the applications and the duration of the treatment were dependent on the location and extent of the lesions. Except for easily treatable lesions, caused by the separation of the tumour epithelium, no complications of local 5-Fu treatment were seen. The visual acuity improved in all 4 patients in whom the cornea was affected. In these premalignant conditions the diagnosis and assessment of the therapy were based on exfoliative cytology and biopsies.
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4/6. Conjunctival rhinosporidiosis.

    rhinosporidium seeberi is the fungus that causes rhinosporidiosis, which affects the mucocutaneous tissue of humans and domestic animals. Ten cases of conjunctival rhinosporidosis have been reported in the united states. This is a case report of conjunctival rhinosporidosis that is believed to be the 11th reported from the united states and the only case reported from arkansas. A clinical and pathologic description of the disease is given.
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5/6. Degeneratio corneae nivalis. snow-crystal degeneration.

    Report of an aged woman in whose corneal stroma point and snow crystal-like, ivory-white, opaque granules developed with calcium granules localized under the conjunctiva. The patient suffered further of general arthrosis and osteopoikilosis in the proximal epiphysis of the femur, demonstrable by X-ray examination. The authors compare the syndrome of their patient with the artificially induced calcification syndrome of rats, which was developed by H. Selye et al, after the administration of isoproterenol, 5-hydroxitriptamin, and dihydrotachysterol to the animals. All three compounds inducing the artificial calcification syndrome, or similar ones, are also normally present in the organism. Their application in the described order causes the abnormal calcification of the connective tissues, probably by the metabolic disturbance of the mucopolysaccharides.
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6/6. A first record from thailand of human external ophthalmomyiasis due to Oestrus ovis.

    A case of external ophthalmomyiasis caused by Oestrus ovis was first reported from Lopburi Province, Central part of thailand, in January, 1997. A 18-year-old man presented with a several hours history of foreign body sensation in his left eye accompanied by irritation. Eight Oestrus ovis first-instar larvae were removed from lower palpebral conjunctiva. Symptoms and clinical signs resolved in 24 hours after mechanical removal of the larvae. There was no history of contact fly and domestic animals. The larvae were identified by light microscopic examination.
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