Cases reported "Contracture"

Filter by keywords:



Filtering documents. Please wait...

1/14. Surgical treatment of pseudosyndactyly of the hand in epidermolysis bullosa: histological analysis of an acellular allograft dermal matrix.

    Recessive dystrophic epidermolysis bullosa is an inherited mechanobullous disorder of skin and mucous membranes. The most striking clinical characteristic of the disease is the formation of blisters following trivial trauma. Repeated cycles of blistering and scarring result in gradual encasement of the hand in an epidermal "cocoon." The authors treated an 11-year-old boy with recessive dystrophic epidermolysis bullosa who presented with hand contractures and interdigital pseudosyndactyly. Treatment included release of contractures and application of a biosynthetic dermal analog. This report is a histological analysis of the dermal matrix 1 year after initial placement of the allograft. Fibroblasts repopulating the dermal allograft had a normal synthetic phenotype and lacked the myofibroblastic features seen in the ungrafted control biopsy. collagen and elastin in the repopulated dermal allograft had normal dermal orientation and maturity in contrast to the sparse, immature collagen and lack of elastin compared with the dermis of an ungrafted control region. Results of this histological study indicate that treatment of recessive dystrophic epidermolysis bullosa with an acellular human dermal allograft may restore some features of normal dermal architecture. Although the initial results are encouraging, longer follow-up is required before definitive conclusions can be made.
- - - - - - - - - -
ranking = 1
keywords = membrane
(Clic here for more details about this article)

2/14. A new technique to resurface wounds with composite biocompatible epidermal graft and artificial skin.

    BACKGROUND: The incorporation of cultured epidermal autograft on the neodermis of artificial skin (Integra, Integra LifeSciences, Plainsboro, NJ) has been met with some difficulties. A new engraftment technique to resurface the wounds with Integra and composite biocompatible epidermal graft (CBEG) has been successfully applied on three patients for elective reconstructive procedures. methods: A small skin biopsy was taken from the normal edge of the lesion for keratinocytes and dermal fibroblast cultures 2 weeks before surgery. When sufficient cells were grown, the patient was admitted for the excision of the lesions or scars. The wounds of the patients, ranging from 125 to 250 cm2, were covered with Integra. When the neodermis of the Integra was fully vascularized, the silicone membrane of the Integra was removed and replaced with the CBEG, which consisted of autologous keratinocytes cultivated on a hyaluronate-derived membrane (Laserskin; Fidia Advanced biopolymers, Abano Terme, italy)) using human dermal fibroblasts as a feeder layer. RESULTS: Clinically, there was good initial "take" of the CBEGs in these three patients, ranging from 50% to 100%. biopsy specimens of the grafted wounds were taken 1 to 3 weeks after the application of the CBEGs. Epithelialization was noted in all patients. CONCLUSION: This engraftment technique has several advantages. The CBEG is much easier to handle than the conventional cultured epidermal autograft. It eliminates the invasive second procedure for skin harvesting, with resulting pain and scarring. The application of the CBEG can be easily performed at the bedside.
- - - - - - - - - -
ranking = 2
keywords = membrane
(Clic here for more details about this article)

3/14. Capsular peeling in anterior capsule contraction syndrome: surgical approach and histopathological aspects.

    We present 4 cases of anterior capsule contraction syndrome in which progressive shrinkage of the anterior capsulorhexis developed after uneventful phacoemulsification. Three eyes were pseudophakic, and 1 eye remained aphakic. The newly formed membrane was surgically peeled from the anterior capsule, restoring the capsular bag.
- - - - - - - - - -
ranking = 1
keywords = membrane
(Clic here for more details about this article)

4/14. Retinal contraction and metamorphopsia scores in eyes with idiopathic epiretinal membrane.

    PURPOSE: Using M-charts (Inami Co., tokyo, japan), which were developed by the authors to measure metamorphopsia, and image-analysis software, which was developed to quantify retinal contraction, the authors investigated the relationship between the degree of retinal contraction and the degree of metamorphopsia in eyes with idiopathic epiretinal membrane (ERM). methods: This study was conducted in 29 eyes with ERM (29 patients, 20 women; mean age, 62.1 /- 8.6 years) observed for at least 3 years (mean, 3.55 /- 0.6 years) after diagnosis. Horizontal (MH) and vertical (MV) metamorphopsia scores were obtained with the M-charts. Horizontal and vertical retinal contraction due to ERM was measured by using image-analysis software developed by the authors to calculate horizontal and vertical components of changes in the locations of retinal vessels on sequential fundus images. RESULTS: There was a significant (P < 0.01) positive correlation between the degree of retinal contraction and metamorphopsia score. In addition, there were significant positive correlations between horizontal contraction of the retina and the MV score (P < 0.01) and between vertical contraction of the retina and the MH score (P < 0.05). No significant correlations were found between change in the metamorphopsia score and change in visual acuity or mean defect. CONCLUSIONS: Metamorphopsia scores correlate well with measurements of retinal contraction due to idiopathic ERM. Using M-charts is a simple and useful method for quantitatively monitoring metamorphopsia in patients with ERM.
- - - - - - - - - -
ranking = 1660.662467921
keywords = epiretinal membrane, epiretinal, membrane
(Clic here for more details about this article)

5/14. hand involvement in paraneoplastic syndrome: a case report.

    Cutaneous paraneoplastic syndromes are skin and mucous membrane changes that are associated with cancer. We report a previously healthy 76-year-old man who developed marked finger and thumb contracture, pain, and hypersensitivity of both hands who was diagnosed subsequently as having gastric carcinoma with colonic metastasis. After the gastrointestinal tumors were resected the finger and thumb contracture lessened and the pain eased. Both the temporal relationship between the changes in the hand and the neoplasm and the improvement after resection suggest a paraneoplastic syndrome.
- - - - - - - - - -
ranking = 1
keywords = membrane
(Clic here for more details about this article)

6/14. Para-alar crescentic subcutaneous pedicle flap for severe stenosis of anterior nares.

    Atresia and stenosis of the anterior nares caused by scar contracture is one of the intractable conditions that may arise after facial injury. Using the standard surgical methods, such as mucous membrane and/or skin graft and intranasal local flap, the new nostril has a tendency to restenose. Para-alar crescentic subcutaneous pedicle flap, which was intended to cover the skin defects in and around the philtrum, was applied to treat severe stenosis of the nostril caused by scar contracture. The procedure resulted in improvement of nasal obstruction with satisfactory postoperative appearance of the external nose. This article presents an operative technique using this flap for severe stenosis of anterior nares.
- - - - - - - - - -
ranking = 1
keywords = membrane
(Clic here for more details about this article)

7/14. pronation contracture of the forearm due to iatrogenic scar formation of the distal membranous part of the forearm interosseous membrane.

    A case of successful treatment of pronation contracture of the forearm due to iatrogenic scar formation in the distal membranous part of the interosseous membrane of the forearm is presented and the management of this problem is discussed.
- - - - - - - - - -
ranking = 5
keywords = membrane
(Clic here for more details about this article)

8/14. epiretinal membrane contracture associated with macular prolapse.

    We treated two patients with annular epiretinal membranes that produced unusual macular morphologic characteristics. contracture of the membranes caused herniation of macular tissue through a hole in the center of the membrane. The membranes were removed surgically, and ultrastructural analysis disclosed cells with properties resembling myofibroblasts and apparent new vitreous collagen. contracture of the cellular components probably produced tangential traction on the retina, which caused prolapse of the retinal tissue through a central defect in the membrane.
- - - - - - - - - -
ranking = 1015.2762760238
keywords = epiretinal membrane, epiretinal, membrane
(Clic here for more details about this article)

9/14. Paucity of secondary synaptic clefts in a case of congenital myasthenia with multiple contractures: ultrastructural morphology of a developmental disorder.

    A new form of congenital myasthenia is described. An infant whose foetal movements during pregnancy had been weak presented at birth with muscle weakness and multiple contractures of the lower limbs. The clinical course was characterised by myasthenic crises during febrile illnesses. Neurophysiological studies demonstrated a decremental response at 2-3 HZ stimulation; this effect was reversed by edrophonium iv. At the age of eight months, a biopsy from the soleus muscle showed a predominance of type I fibres and variation in fibre diameters was slightly increased. Ultrastructural studies of the motor endplates revealed a marked reduction of post-synaptic membrane lengths with paucity of secondary clefts. Signs of focal degeneration were absent. The picture was reminiscent of foetal neuromuscular junctions. A developmental disorder of the postsynaptic membrane was considered to be the basic cause of the neuromuscular transmission defect.
- - - - - - - - - -
ranking = 2
keywords = membrane
(Clic here for more details about this article)

10/14. Rotatory contracture of the forearm.

    We saw seven patients with an idiopathic progressive loss of rotation of the forearm, occurring primarily during adolescence and manifested principally by a gradual loss of supination. There were secondary developmental abnormalities of the radial head and of the ulna (distal bowing) in four patients. Six surgical procedures were performed on five of the seven patients, consisting of combinations of sectioning of the quadrate ligament, release of the interosseous membrane, and ostecotomy and compression-plate fixation of the distal end of the ulna. There was functional improvement in four patients. Release of the quadrate ligament provided the greatest improvement, but that release alone was of minimum value. We concluded that a contracted quadrate ligament may be an important deterrent to supination of the forearm, but distortion of the radial head, curvature of the ulna, and contracted soft tissues in the interosseus space and distal radio-ulnar joint also are contributory factors.
- - - - - - - - - -
ranking = 1
keywords = membrane
(Clic here for more details about this article)
| Next ->


Leave a message about 'Contracture'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.