Cases reported "Demyelinating Diseases"

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11/19. neuromyelitis optica (Devic's syndrome): not always multiple sclerosis.

    A patient is presented with clinical signs and symptoms of neuromyelitis optica (Devic's syndrome). The clinical findings, the cerebrospinal fluid findings and the magnetic resonance imaging findings in our patient demonstrate that neuromyelitis optica is not always a form of multiple sclerosis. It can also be a manifestation of other demyelinating diseases, for example Disseminated encephalomyelitis.
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keywords = neuromyelitis optica, neuromyelitis, optica
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12/19. neuromyelitis optica in the old age: a clinico-pathological contribution.

    We present a case of neuromyelitis optica (NMO) in a previously healthy 64-year-old woman. While CT scan and MRI investigations of the brain as well as myelography were normal, CSF revealed a pathological increase of IgG. Notwithstanding an intensive steroid therapy the patient died after 4 1/2 months. Microscopic examination showed, besides extensive demyelination of the optic nerves and spinal cord (especially in its cervico-dorsal tract), several small demyelinating plaques in the white matter of the pons and near the right lateral ventricle. These findings confirm once again that NMO is a clinical variant of multiple sclerosis and that this disease may make it first appearance at an old age.
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ranking = 0.55317562567472
keywords = neuromyelitis optica, neuromyelitis, optica
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13/19. neuromyelitis optica (Devic syndrome) in a 12-year-old male with complete recovery following steroids.

    neuromyelitis optica is one of the rarest forms of central nervous system demyelinating disease. It is particularly infrequent in Western countries and complete recovery is rare. We report a 12-year-old boy with neuromyelitis optica which occurred shortly after an upper respiratory infection. magnetic resonance imaging revealed several small areas of increased signal intensity within the cerebral and cerebellar white matter on T2-weighted images. The patient recovered completely following treatment with high-dose prednisone.
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ranking = 0.57976343851208
keywords = neuromyelitis optica, neuromyelitis, optica
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14/19. neuromyelitis optica: a case report from india.

    A young Indian male was admitted for paraplegia of acute onset and with bilateral optic neuritis. The diagnosis of neuromyelitis optica was made. This is possibly the first case report of its kind from india.
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ranking = 0.55317562567472
keywords = neuromyelitis optica, neuromyelitis, optica
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15/19. neuromyelitis optica with unusual vascular changes.

    A case of neuromyelitis optica had strikingly increased numbers of thickened, hyalinized small blood vessels, which were associated with cystic degeneration in the cervical spinal cord and the optic chiasm. These findings support the contention that neuromyelitis optica is a clinical syndrome rather than a distinct nosologic entity.
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ranking = 1
keywords = neuromyelitis optica, neuromyelitis, optica
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16/19. neuromyelitis optica in the elderly.

    blindness and quadriparesis developed in an elderly woman whose symptoms began at the age of 69 years. Postmortem examination revealed extensive demyelinative lesions in the optic nerves and spinal cord. The clinical and pathologic findings were consistent with the diagnosis of neuromyelitis optica ( NMO ). This case serves to document that NMO and presumably typical multiple sclerosis can occur initially at an advanced age.
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ranking = 0.55317562567472
keywords = neuromyelitis optica, neuromyelitis, optica
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17/19. neuromyelitis optica (Devic's syndrome) in two sisters.

    neuromyelitis optica (Devic's syndrome) typically occurs in a sporadic pattern. We studied the disorder in two sisters, ages 6 and 10 years, who presented with sudden loss of vision at age 3 years, followed 5 months later by a transverse myelopathy. The older girl had only light perception in either eye, persistent paraparesis and progressive scoliosis; her sister had a visual acuity of 20/200 in both eyes and mild spinal cord dysfunction. Results of electrodiagnostic tests correlated well with the severity of clinical neurologic deficits and provided objective estimates of the extent of tissue damage in both the optic nerves and the spinal cord. The presence of Devic's syndrome in these two sisters could be coincidental; however, the possibility of a shared genetic factor(s) should be considered.
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ranking = 0.1329390641868
keywords = optica
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18/19. multiple sclerosis and neuromyelitis optica. Case report and speculation.

    Among the indigenous people of tropical and subtropical countries neuromyelitis optica is more common than multiple sclerosis (MS), which is exceptionally rare. Alternatively, one might conclude that when MS does occur in these countries it usually assumes the spinal-optic form. The evidence on which these statements are based is reviewed, and 6 cases from Natal are presented. These observations could have a bearing on the pathogenesis and epidemiology of MS.
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ranking = 2.2341218716264
keywords = neuromyelitis optica, neuromyelitis, optica
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19/19. A case of neuromyelitis optica (Devic's syndrome) in systemic lupus erythematosus. Clinicopathologic report and review of the literature.

    An interesting case of systemic lupus erythematosus (SLE) is presented in which the clinical onset of myelopathy strongly suggested demyelinating disease. Later, intracranial hypertension developed on two occasions. Postmortem examination showed the systemic lesions of SLE. In addition, demyelinating lesions were found in the spinal cord and the optic nerve, the neuropathologic picutre of Devic's syndrome, a variant of multiple sclerosis. We question whether some of the cases showing necrotic myelopathy might have an autoimmune pathogenesis.
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ranking = 1.7872974973011
keywords = neuromyelitis optica, neuromyelitis, optica
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