Cases reported "Epidural Neoplasms"

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1/23. Infiltrating extradural spinal angiolipoma.

    BACKGROUND: Angiolipomas are considered to be rare. They are benign mesenchymal tumors generally located in the subcutaneous tissue of trunk and limbs. methods: The authors report a thoracic epidural angiolipoma mimicking a vertebro-epidural metastasis. The patient suffered from medullary compression related to an extradural mass in T6. RESULTS: Pathological ex-, amination was obtained from tumoral samples. They consisted of mature adipose tissue with numerous sections of abnormal vascular channels. CONCLUSIONS: Reviewing literature particular attention is paid to some questions raised in connection with different kinds of vertebro-epidural tumors. The authors give importance to relationships between angiolipomas and angiomyolipomas using MRI as a tool in differential diagnosis. Pathogenesis is evokated especially regarding the role of corticotherapy, the case herein reported lying within this therapeutical context.
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ranking = 1
keywords = ewing
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2/23. Intraspinal primitive neuroectodermal tumour: report of two cases and review of the literature.

    Two patients with primary intraspinal primitive neuroectodermal tumour are presented. In a 32-year-old man, the tumour evolved intradurally from a sacral nerve root. Despite repeated surgery and radiochemotherapy, the patient suffered multiple intraspinal tumour relapses and intracranial seedings, and died 29 months after the first diagnosis. In a 17-year-old male adolescent, the tumour was located in the lumbar epidural space, extending into the paraspinal muscles. Following resection and radiochemotherapy, the patient is free from disease 23 months after the initial presentation. The clinical, radiological, histopathological and cytogenetic findings of both patients are presented and the relevant literature is reviewed. Particular attention is given to the histogenetic relationship between peripheral primitive neuroectodermal tumour and Ewing's sarcoma.
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ranking = 1.4606931715551
keywords = sarcoma
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3/23. Intravascular papillary endothelial hyperplasia causing cauda equina compression: case report.

    OBJECTIVE AND IMPORTANCE: Intravascular papillary endothelial hyperplasia (Masson's vegetant hemangioendothelioma) is a rare condition affecting the neuraxis. In the literature, only one case of this lesion involving the vertebral canal with spinal cord compression has been reported. We present a case of cauda equina compression due to this abnormality. CLINICAL PRESENTATION: A 17-year-old boy was admitted at our hospital with pain, numbness, paresis of the left lower extremity, and bladder dysfunction of approximately 1 month's duration. Computed tomography and magnetic resonance imaging of the spine revealed a tumor within the spinal canal at the T12-L1 level. INTERVENTION: The patient underwent a T12-L1 laminectomy. An epidural red nodular tumor was visualized and totally resected. The findings of the pathological examination were compatible with intravascular papillary endothelial hyperplasia. At follow-up examination 1 month after the operation, the patient had complete resolution of the pain, and the motor deficit and bladder dysfunction had improved significantly. CONCLUSION: This rare benign vascular lesion may be clinically and histopathologically mistaken for an angiosarcoma. Because the intravascular papillary endothelial hyperplasia can be cured by complete surgical resection, it is important to distinguish between these two lesions to avoid inappropriate aggressive treatment.
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ranking = 1.4606931715551
keywords = sarcoma
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4/23. Spinal epidural extraskeletal Ewing sarcoma: MR findings in two cases.

    SUMMARY: We report the CT myelography and MR findings of two cases of extraskeletal Ewing sarcoma involving the spinal epidural and paravertebral spaces in a middle-aged man (case 1) and a young woman (case 2). In both cases CT myelography showed epidural and paravertebral masses on one side, with widening of the ipsilateral neural foramina at the C5-C6 level in case 1 and at the C7-T1 level in case 2. On MR images, the masses were isointense to muscle on T1-weighted images, hyperintense on T2-weighted images, and showed moderate enhancement on contrast-enhanced T1-weighted images. In one case, all pulse sequences showed linear signal voids, representing the vertebral artery encasement within the mass. The intradural component connected with the main mass was detected in the other case.
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ranking = 7.3034658577756
keywords = sarcoma
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5/23. Primary spinal epidural extraosseous Ewing's sarcoma: report of five cases and literature review.

    Ewing's sarcoma is the most common malignant bone tumour occurring in children and adolescents and exists in two different clinicopathological entities: osseous Ewing's sarcoma (OES) and extraosseous Ewing's sarcoma (EES). Five cases of primary epidural EES are described, which presented with non-specific symptoms leading to a long diagnostic delay. The median age at diagnosis was 22 years (range 13-36 years). The median diagnostic delay was 3 months. All patients had one or more neurological deficits. All underwent surgical exploration with a laminectomy and partial resection followed by adjuvant radiotherapy to a dose of 46-50 Gy and chemotherapy with VAC (vincristine, adriamycin and cyclophosphamide) alternating with ice (ifosphamide, cisplatin and etoposide) for at least six cycles. The mean follow-up period is 21.2 months (range 11-32 months). Four of the five patients achieved a complete remission and are disease free at the time of writing this report. Two patients have a residual neurological deficit--both having presented with long history of neurological deficit. Primary spinal epidural EES should be suspected whenever young patients present with back pain and/or radicular pain, have abnormal neurology and an extradural mass is demonstrated on MRI. Surgical excision followed by adjuvant radiotherapy (50 Gy) and combination chemotherapy (VAC alternating with ice) achieved local and systemic control in these patients. A greater number of patients and longer follow up are required to evolve a generally accepted treatment policy for this aggressive but potentially curable malignancy.
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ranking = 10.224852200886
keywords = sarcoma
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6/23. Multiple granulocytic sarcomas in acute myeloblastic leukemia with simultaneous occurrence of t(8:21) and trisomy 8.

    This report describes a rare case of multiple intracranial, extradural chloromas. A five year old African American male presented with headache, fever, and vomiting. The peripheral blood smear showed myeloblasts with Auer rods. The CTscan of the brain showed three intracranial, epidural lesions as well as soft tissue masses in the retroorbital region and sphenoid sinuses. CTscan of the chest showed two paraspinal epidural thoracic masses. pathology of the epidural intracranial mass revealed a granulocytic sarcoma. cytogenetic analysis showed simultaneous occurrence of t(8;21) and trisomy 8. Following induction therapy, he is now in complete remission.
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ranking = 7.3034658577756
keywords = sarcoma
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7/23. Spinal epidural granulocytic sarcoma preceding acute myelogenous leukemia.

    A rare case of spinal epidural granulocytic sarcoma (GS) preceding acute myelogenous leukemia is described. A 10-year-old boy presented with lower leg weakness. The initial diagnosis was a histiocytic lymphoma, and he was treated accordingly. No evidence of bone marrow involvement was found at that time. The correct diagnosis of epidural GS was made possible in retrospect by using immunoperoxidase staining for lysozyme fourteen months later when the patient showed the full-blown features of leukemia. This rare tumor should be considered in the differential diagnosis of an epidural mass with cord compression in patients with or even without acute leukemia, because early diagnosis followed by appropriate combined chemotherapy and radiation may obviate surgical intervention and eventually prevent leukemic transformation.
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ranking = 7.3034658577756
keywords = sarcoma
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8/23. Spinal epidural rhabdomyosarcoma.

    We report an extremely rare case of rhabdomyosarcoma in the lower cervical and upper thoracic spine. The MR imaging appearance of the lesion was nonspecific, and different from the one previously reported. The majority of the tumor was removed surgically less than a month from the onset of symptoms. Treatment was continued with spinal irradiation and chemotherapy, however diffuse leptomeningeal metastases were found six months later.
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ranking = 7.3034658577756
keywords = sarcoma
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9/23. Spinal epidural synovial sarcoma: a case of homogeneous enhancing large paravertebral mass on MR imaging.

    We report the MR imaging findings in a 44-year-old man with a low-grade synovial sarcoma. There was a right-sided epidural and paravertebral mass, widening of the ipsilateral neural foramen at the L4-L5 level, and focal erosion of the right superior articular process of the L5 vertebra. The mass was relatively homogeneous, hyperintense to muscle and isointense to fat on T2-weighted images, and isointense to muscle on T1-weighted images, and it demonstrated moderate homogeneous enhancement.
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ranking = 7.3034658577756
keywords = sarcoma
(Clic here for more details about this article)

10/23. An isolated nonosseous metastasis to the epidural space from an osteogenic sarcoma.

    Metastatic disease from osteosarcoma most commonly occurs in the lung and bony sites. Both primary spinal osteosarcomas and spinal metastatic lesions are rare. A case is reported of a nonosseous epidural metastatic lesion from osteosarcoma. It was visualized best by metrizamide-enhanced computed tomographic scanning. The patient symptomatically improved with excision of the lesion although there was massive recurrence despite combined therapy.
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ranking = 10.224852200886
keywords = sarcoma
(Clic here for more details about this article)
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