1/6. aspergillus niger endophthalmitis after cataract surgery.We report a 65-year-old diabetic woman who developed aspergillus niger endophthalmitis after cataract surgery. She presented 9 weeks after extracapsular cataract extraction with a black growth covering the cornea and moderate echoes in the vitreous on ultrasonography. After microbiological confirmation of fungal endophthalmitis, the patient received intravitreal amphoterecin B 5 micro g, topical natamycin 5% hourly, atropine 1% 3 times, and oral antifungal therapy. The patient was told the visual prognosis and was advised to have penetrating keratoplasty and vitrectomy, which she refused.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
2/6. Conjunctival aspergilloma with multiple mulberry nodules: a case report.A 30-year-old healthy female presented with a 1-year history of chronic mucous discharge, tearing, and irritation in the left eye. Slit-lamp examination revealed severe papillary and follicular reaction surrounding a movable subconjunctival mass on the left upper tarsal conjunctiva. Incision and curettage were performed to establish the diagnosis. Multiple peculiar black mulberry nodules were obtained. The clumps of septate hyphae seen with periodic acid-Schiff stain were characteristic of fungus ball (aspergilloma). The patient's symptoms improved significantly after surgery without any antifungal therapy. Although rarely reported, aspergillus is a common fungus in the conjunctiva that may seed into the subconjunctiva. We present this case to remind ophthalmologists of such a rare cause of recalcitrant conjunctival inflammation in immunocompetent patients.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
3/6. Clinical and experimental mycotic corneal ulcer caused by aspergillus fumigatus and the effect of oral ketoconazole in the treatment.aspergillus fumigatus was isolated from a case of keratomycosis. The patient, a 12-year-old boy presented with large corneal ulcer with hypopyon. The direct microscopic examination of scrapings revealed hyaline, septate mycelium. in vitro some antimycotics (amphotericin b,5-fluorocytosine, oxiconazole, amorolfine and ketoconazole) were tested against A. fumigatus by agar dilution method. ketoconazole with minimum inhibitory concentration of 30 micrograms/ml after 11 days of incubation was most effective against A. fumigatus. Experimental corneal ulcer was produced by injecting intralamellary spore suspension (2.5 x 10(6) c.f.u.) into the right eyes of previously immunosuppressed albino and black wild types of rabbits. The extent of ocular infection was graded up to 32 days. Histopathologic examination showed infiltration and large destruction of corneal stroma. Oral ketoconazole therapy exhibited partial response followed by relapse. The black type of rabbit appeared more suitable as an animal model for mycotic keratitis.- - - - - - - - - - ranking = 2keywords = black (Clic here for more details about this article) |
4/6. A case of mycotic keratitis caused by fusarium solani.A 36-year-old black man, without history of systemic disease or ocular trauma developed a corneal infection in his left eye. He was treated with antibacterial antibiotic and corticosteroids for one month prior to diagnosis. Fungal hyphae and chlamydospores were found in a KOH preparation of the corneal scrapings, and positive cultures for fusarium solani were obtained in Sabouraud dextrose agar. It is emphasized the cautious use of antibiotics and steroids in corneal diseases, and the need of considering the involvement of opportunistic fungi in the etiology of these infections.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
5/6. Intraconal amphotericin b for the treatment of rhino-orbital mucormycosis.Rhino-orbital-cerebral mucormycosis is a disease that is frequently fatal. A 39-year-old man with diabetic ketoacidosis was referred to the authors' ophthalmic service with fever, orbital apex syndrome in the right eye, lethargy, and a black eschar in the palate. He was treated with systemic and local (intraconal) amphotericin b and his ketoacidosis was controlled; exenteration was not performed. biopsy of the palate proved mucormycosis. Eighteen months later the patient was still alive and had a blind, anatomically preserved right eye with ptosis and intact extraocular muscle function without proptosis or pain. The authors propose this alternative means of treatment to achieve higher doses of the drug at the site of infection and better cosmetic and psychological results.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |
6/6. Black corneal ulcer.PURPOSE: To discuss the etiology of an unusual finding of black color in a corneal ulcer. methods: Smear examination and culture of the corneal scraping were undertaken. RESULTS: The causative organism was found to be Aspergillus ruger. CONCLUSION: Black color in the corneal ulcer is attributed to Aspergillus niger.- - - - - - - - - - ranking = 1keywords = black (Clic here for more details about this article) |