Cases reported "Eye Manifestations"

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1/56. Ocular manifestations of hypercupremia associated with multiple myeloma.

    Extensive copper infiltration of descemet membrane of the central cornea and of the anterior and posterior surfaces of the lens is associated with marked hypercupremia related to an abnormal immunoglobulin. observation of this spectrum of ophthalmic changes in an apparently well middle-aged woman heralded the diagnosis of a unique variety of multiple myeloma. ( info)

2/56. histiocytosis X: a case report.

    The rare disease entity of histocytosis X is presented. Features of unusual interests in the present case were the bilateral exophthalmus as the presenting sign, fever, ottorhoea and involvement of lung and long bones. ( info)

3/56. The clinical spectrum of Sweet's syndrome (acute febrile neutrophilic dermatosis)-a report of eighteen cases.

    Eighteen cases of Sweet's syndrome are described. This is the largest series so far reported and the first from the tropics. The essential features are the characteristic morphology, the histological appearances, the dramatic response to corticosteroids and the absence of scarring. attention is drawn to the frequent involvement of the eyes and joints during the course of the illness. fever and neutrophilia were found less frequently than a raised ESR or a preceding upper respiratory tract or skin infection. The term Sweet's syndrome is preferred to acute febrile neutrophilic dermatosis. The frequency of occurrence of different clinical manifestations is discussed. ( info)

4/56. Thalamic tumors in childhood. Clinical, laboratory, and therapeutic considerations.

    Eighteen cases of primary thalamic tumor occurring in children (ages 2 1/2 to 12 1/2 years) were studied retrospectively. Among the clinical features of this group that contrasted with adults having similar tumors were a shorter duration of symptoms before diagnosis and a higher incidence of motor abnormalities in the early illness. In several cases, symptoms and signs usually associated with cerebellar disorders predominated. Arteriography or gas encephalography or both were diagnostic in all but two cases. The electroencephalogram, abnormal in slightly more than 70% of the cases, suggested a thalamic mass in more than one third. A highly specific EEG feature was the presence of spindles while patients were awake. In 15 cases there was some evidence of ventricular dilation and nine of these later required shunts. In addition to shunting procedures, therapy included x-ray therapy alone or with craniotomy or craniotomy alone. ( info)

5/56. Ocular manifestations of Gaucher's disease.

    A 27-year-old woman not only had the usual clinical and laboratory features of the adult form of Gaucher's disease but also had typical pingueculae and a peculiar lesion with a pigmented temporal edge in the fundus of her left eye. Bone-marrow aspiration demonstrated infiltration by Gaucher's cells and a biopsy of the conjuctival masses disclosed areas of infiltration by Gaucher's cell beneath normal epithelium. ( info)

6/56. sturge-weber syndrome.

    Encephalotrigeminal angiomatosis (sturge-weber syndrome) is described with a typical case history. ( info)

7/56. Evolution of the retinal black sunburst in sickling haemoglobinopathies.

    In a prospective study of 38 patients, who were initially selected as being at an early stage of sickling retinopathy, three developed circular black chorio-retinal scars (black sunbursts) during a period of 6 to 24 months. These lesions appear to be the sequelae of intraretinal and subretinal haemorrhage. They occur in the fundus periphery and do not interfere with vision. ( info)

8/56. Menkes' kinky hair disease: a light and electron microscopic study of the eye.

    light and electron microscopic studies of the ocular tissue of a case of Menkes' kinky hair disease are described. The copper deficiency responsible for this systemic and neurologic disease appears to cause a progressive degeneration of retinal ganglion cells, loss of nerve fibers, and optic atrophy. The pigment epithelium is also abnormal with only small and irregular melanin granules present among electron-dense inclusion bodies. Abnormal elastica is present in Bruch's membrane. ( info)

9/56. Orbital involvement in Riedel's struma.

    A patient with Riedel's struma had bilateral orbital involvement. The histopathological findings were the same in the thyroid and lacrimal glands. ( info)

10/56. Neurilemomas of the infratemporal space: report of a case and review of the literature.

    We describe a case of a trigeminal neurilemoma in an adolescent girl. It primarily involved the infratemporal space and extended into the middle cranial fossa, and began with only ocular symptoms. The surgical management is emphasized, illustrating the approach to the infratemporal fossa through a wide osteotomy of the coronoid process of the mandible without the need for mandibular split. ( info)
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