1/120. Ultrasonographically guided injection of corticosteroids for the treatment of retroseptal capillary hemangiomas in infants.PURPOSE: Injection of corticosteroids is a well-documented and successful mode of treatment for periorbital capillary hemangiomas. Because of the greater potential risk involved with retrobulbar injections, no prior study has described this treatment for tumors located behind the orbital septum. Although retroseptal intraorbital capillary hemangiomas comprise only 7% of all adnexal capillary hemangiomas, complications such as optic nerve compression or astigmatism may necessitate treatment. methods: Three patients with deep orbital hemangiomas that caused vision-threatening complications were treated with intralesional injections of triamcinolone and betamethasone. Orbital injection was performed with use of real-time ultrasonographic guidance of the needle. This technique was valuable in providing continuous, accurate, and safe advancement of the needletip in the orbit to avoid the globe and orbital walls. ultrasonography also permitted precise placement of the needle tip within the tumor and visualization of the injected material. RESULTS: Significant improvement was demonstrated in all cases on the basis of both ultrasonographic measurements and regression of clinical manifestations such as astigmatism, chemosis, proptosis, and optic nerve pallor. No complications were noted. CONCLUSION: Intralesional injection of corticosteroids to treat retroseptal and retrobulbar capillary hemangiomas was found to be a safe and effective treatment modality in our patients. Positioning of the injecting needle was guided by ultrasonography.- - - - - - - - - - ranking = 1keywords = optic (Clic here for more details about this article) |
2/120. T-cell lymphoproliferative disorder of vitreous associated with mycosis fungoides.59-year-old man with a history of mycosis fungoides developed loss of visual acuity and visual field in the left eye. Epiretinal lesions were present in the right eye and multifocal choroidal lesions, optic disc edema, and vitritis were present in the left eye. A diagnostic vitrectomy was performed and cytologic examination of the vitreous confirmed the diagnosis of T-cell lymphoproliferative disorder. Systemic and intrathecal chemotherapy resulted in marked improvement in ocular signs and symptoms. At last follow-up, the patient was found to have improved visual acuity in the left eye; however, significant worsening of his systemic condition developed and he died shortly thereafter.- - - - - - - - - - ranking = 0.50224889478348keywords = optic, edema (Clic here for more details about this article) |
3/120. Cavernous haemangioma of the retina and optic disc. A report of three cases and a review of the literature.We report characteristics of three cases of cavernous haemangioma of the retina, bringing to 37 the number now reported in the available literature. This rare, benign, congenital malformation is non-progressive, usually unilateral, somewhat more frequent in women, and rarely a source of intraocular haemorrhage. The fluorescein angiographic features include a normal arterial and venous supply, extraordinarily slowed venous drainage, no arterio-venous shunting, no disturbances of vascular permeability, and no secondary retinal exudation. Almost always, isolated clusters of vascular globules with plasma/erythrocyte sedimentation surround the main body of the malformation. These findings differentiate the anomaly from other retinal vascular diseases. Therapeutic intervention is seldom necessary.- - - - - - - - - - ranking = 2keywords = optic (Clic here for more details about this article) |
4/120. Vascular anastomoses between the iris and persistent hyperplastic primary vitreous.Prominent radial iris blood vessels created small but definite pupillary notches in five children with persistent hyperplastic primary vitreous and persistence of the tunica vasculosa lentis. Detection of these abnormal iris vessels suggested the presence of persistent hyperplastic primary vitreous and related syndromes even when the diagnosis was obscured by the presence of an opaque lens. These vessels represented early developmental arrest and may have been associated with abnormal development of the macula and optic nerve. Surgical and amblyopia therapy, therefore, may not provide useful vision, and should be undertaken with caution.- - - - - - - - - - ranking = 0.5keywords = optic (Clic here for more details about this article) |
5/120. Optic neuropathy and central retinal artery occlusion in non-Hodgkin lymphoma.We report a patient with systemic large cell non-Hodgkin lymphoma in remission who presented with the rare combination of optic neuropathy and central retinal artery occlusion. Another unusual feature of this case is the lack of enhancement in the affected region on magnetic resonance imaging only hours after the first dose of steroids. Despite prompt treatment with steroids and radiotherapy, lymphomatous infiltration of the meninges developed 2 months later and was ultimately fatal.- - - - - - - - - - ranking = 0.5keywords = optic (Clic here for more details about this article) |
6/120. Cavernous hemangioma of the retina: report of four cases.Four patients had cavernous hemangiomas of the retina. The lesions, which usually occur in asymptomatic individuals, are unusual hamartomas comprised of saccular aneurysms containing venous blood and located on the surface of the retina or at the optic nervehead. Two patients had photocoagulation to destroy the lesions. In one patient, the lesion was totally destroyed after treatment to it and to the surrounding retina; in the second patient, a portion of the lesion had enlarged greatly when examined 5 years after photocoagulation. The hemangiomas of the other 2 patients have been observed without therapeutic intervention--the course we prefer for the majority of cases.- - - - - - - - - - ranking = 0.5keywords = optic (Clic here for more details about this article) |
7/120. Infiltrative retinopathy in systemic lymphoma.A 48-year-old woman with a diffuse well-differentiated lymphocytic lymphoma developed an unusually extensive bilateral infilfrative retinopathy during a period of quiescence of her systemic illness. Although radiation therapy to each orbit initially induced clearing of the infiltration and significant improvement in visual acuity, late visual acuity loss due to retinal and optic nerve changes ensued.- - - - - - - - - - ranking = 0.5keywords = optic (Clic here for more details about this article) |
8/120. Clinicopathologic case reports: optic nerve head metastasis.A case of tumor metastasis from carcinoma of the lung directly to the cribriform plate is described. Retina and optic nerve were involved, but there was no evidence of tumor invasion of the choroid. It is postulated that the original tumor embolus lodged in a cribriform branch of the arterial circle of Zinn or in the central retinal vessels.- - - - - - - - - - ranking = 0.5keywords = optic (Clic here for more details about this article) |
9/120. New findings in the chromosome 13 long-arm deletion syndrome and retinoblastoma.New clinical and pathologic findings in patients with deletion of the long arm of chromosome 13 (13q-) include optic nerve hypoplasia and retinal dysplasia. fibroblasts derived from patients with a 13q- syndrome with and without retinoblastoma, as well as from familial and sporadic retinoblastoma, are a useful model for the study of genetic susceptibility to the development of spontaneous and radiation-induced cancers. fibroblasts from patients with hereditary retinoblastoma appear more radiosensitive than fibroblasts from patients with sporadic retinoblastoma or normal control patients.- - - - - - - - - - ranking = 0.5keywords = optic (Clic here for more details about this article) |
10/120. The neuroradiologic evaluation of "optic neuritis".optic neuritis, even when clinically typical, cannot be diagnosed with certainty because mass lesions compressing the anterior visual pathways may mimic it. The radiologist is in a position to assist in identifying such lesions or in ruling them out and thus preventing surgical exploration. While every patient in whom the diagnosis of optic neuritis is entertained should have plain roentgenograms of skull, orbits and optic canals, we have developed a schema for detailed neuroradiologic investigation based on clinical and plain roentgenographic findings. A classification of such lesions by location is illustrated.- - - - - - - - - - ranking = 3keywords = optic (Clic here for more details about this article) |
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