11/43. Irradiation of malignant eyelid melanoma with iodine 125 plaque.We used contact irradiation with iodine 125 seeds to treat a large, exulcerative, nodular, amelanotic malignant eyelid melanoma with metastasis to the regional lymph nodes in an 80-year-old man. The procedure was similar to iodine 125 plaque irradiation of malignant choroidal melanoma; special equipment, however, was needed to protect the eye from radiation exposure. The response of the malignant eyelid melanoma to iodine 125 plaque irradiation was similar to that of malignant melanomas of the choroid. No complications were observed in a follow-up period of 15 months.- - - - - - - - - - ranking = 1keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
12/43. Plastic surgery of cutaneous head and neck tumors. A different view.Plastic surgery is really a multispecialty specialty. It encompasses cosmetic surgery, trauma, congenital anomalies, hand surgery, treatment of burns, genital-urinary reconstruction, as well as cancer ablation and reconstruction. This paper reviews three cases of skin cancer (basal cell carcinoma, squamous cell carcinoma, and melanoma) that had a varied presentation and clinical course.- - - - - - - - - - ranking = 0.11392290536589keywords = melanoma (Clic here for more details about this article) |
13/43. Malignant melanomas of eyelid skin.Four cases of malignant melanoma of eyelid skin are reported. Management of the condition is discussed, with a review of the literature. The conclusions lead us to recommend wide surgical excision for those melanomas arising on the lash margins. If the melanoma is clear of the eyelid margin, smaller margins may be adequate.- - - - - - - - - - ranking = 0.88607709463411keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
14/43. Metastatic melanoma within and to the conjunctiva.Two patients with epibulbar juxtalimbal primary conjunctival melanomas experienced local intralymphatic metastases to the inferior cul-de-sac, and a hematogenous metastasis to the conjunctiva developed in five other patients with cutaneous melanomas. Whether reflective of a local or distant metastasis, all of the lesions histopathologically were located in the substantia propria, and were separated from the overlying epithelium by a thin mantle of collagen. There was no evidence of atypical intraepithelial melanocytic proliferation, as would be expected in association with a primary conjunctival melanoma. Two of the cutaneous metastases exhibited a binodular or multinodular appearance that correlated histopathologically with variably confluent micronodules suggestive of the origin of the clinical lesion from a shower of tumor cell emboli. patients with local intralymphatic spread from a primary conjunctival melanoma may experience additional lesions in the conjunctival sac or eyelid skin and are at risk for regional or distant metastases. They should be examined closely several times a year. The patients with the distant metastases all had their previously diagnosed primary cutaneous tumors on the truncal skin (a similar tendency emerges from a review of previous ocular cases), typically had myriad other cutaneous lesions, and two of them had a neoplastic iridocyclitis and vitreitis. These patients tended to die of the disseminated tumors within 1 year after conjunctival metastases developed.- - - - - - - - - - ranking = 0.91138324292715keywords = melanoma (Clic here for more details about this article) |
15/43. Solitary metastasis of choroidal melanoma to the contralateral eyelid.A 60-year-old man developed a subcutaneous mass in the right lower eyelid 2 1/2 years after enucleation of the left eye for a mixed-cell-type choroidal melanoma. Excision of the subcutaneous eyelid mass revealed the tumor to be a malignant melanoma composed of spindle B cells similar to those in the intraocular tumor. The patient's systemic evaluation, including liver enzymes, has remained normal, with no signs of further metastasis and no evidence of another primary melanoma for 14 months of postexcision follow-up. The significance of the rare occurrence of isolated metastatic melanoma from the choroid of one eye to the eyelid of the other is discussed.- - - - - - - - - - ranking = 1keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
16/43. Primary eyelid malignant melanoma associated with primary conjunctival malignant melanoma.Two patients presented with the unusual occurrence of isolated foci of malignant melanoma of the upper eyelid and ipsilateral inferior conjunctiva. Neither patient had clinical evidence of primary acquired conjunctival melanosis, but in one case there was histopathologic evidence of this condition. The clinical features, histopathologic findings, and possible significance of this unusual occurrence are discussed.- - - - - - - - - - ranking = 1.3797731765844keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
17/43. Metastasis of choroidal melanoma to the contralateral choroid, orbit, and eyelid.A 52-year-old woman was found to have a small juxtapapillary pigmented lesion in the choroid of the left eye. This lesion remained clinically stationary for one year, but subsequent growth prompted enucleation of the eye. The tumour was diagnosed histologically as a choroidal malignant melanoma of mixed cell type. Approximately 52 months later the patient developed proptosis of the contralateral (right) eye. Orbital ultrasonography showed a large mass in the right orbit, which was confirmed by needle biopsy to be a melanoma. In addition the patient was found to have metastatic melanoma to the choroid, right lower eyelid area, and liver. The development of simultaneous orbital, choroidal, and eyelid metastases from a contralateral choroidal melanoma is of ophthalmic interest and appears to be unique.- - - - - - - - - - ranking = 1keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
18/43. Desmoplastic malignant melanoma masquerading as chalazion.Desmoplastic malignant melanoma is a rare and highly malignant tumour, which usually occurs in the head and neck. This is demonstrated by a case history of a patient with this lesion on the lower lid, which has not been previously described in the British ophthalmological literature. The lesion often presents considerable problems of histological diagnosis.- - - - - - - - - - ranking = 1.0126983121937keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
19/43. MR imaging of enucleated human eyes at 1.4 tesla.Proton magnetic resonance images obtained for nine human eyes with various pathology were correlated with histological findings. One eye with retinal gliosis, three eyes with malignant melanoma, one eye with extraocular squamous cell carcinoma, one pair of eyes with incipient senile cataracts, and one pair of eyes with diabetic cataracts were examined at a field strength of 1.4 T using spin-echo and inversion-recovery signal acquisition protocols. Eyes were examined unfixed and within 24 h of enucleation. Most images were characterized by a homogeneous vitreous and a lens made conspicuous by its low-signal intensity. The anterior chamber, ciliary body, and optic nerve could be seen, but the retina and choroidal layers could not be distinguished. The dynamic range of vitreal signal was quite wide and allowed all lesions in this series to be well-contrasted against the vitreous. In addition, lenticular edema accompanying cataract formation gave a strong signal. Signal differences were apparent between paired cataractous lenses with a 1.6% difference in water content. magnetic resonance imaging is a modality that promises good contrast for ocular imaging and sensitive detection of incipient cataractous change.- - - - - - - - - - ranking = 0.20253966243874keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
20/43. Small lymphangiomas of the eyelids.Three patients are described with focal lymphangiomatous lesions of their eyelids. A child with a partially regressed, congenital lesion presented with evidence of recent hemorrhage, while, of two adults with acquired tumors, one had a blue lesion suggesting a malignant melanoma, and the other had a more obviously cystic lesion, suggesting an epidermal or adnexal cyst. In one case, the lesion was situated entirely within the marginal orbicularis striated muscle, and in the other two cases the lesion was restricted to the dermis of the lid. Abrupt change in the coloration of a lesion in the lid should suggest hemorrhage into a preexistent tumor. hemorrhage into lymphangiomas is extremely common, and therefore this vascular tumor should be included in the differential diagnosis of previously nondiscolored lesions. Other vascular tumors, such as capillary, cavernous or venous angiomas would be expected to have a longstanding reddish-blue hue.- - - - - - - - - - ranking = 0.20253966243874keywords = melanoma, malignant melanoma (Clic here for more details about this article) |
| <- Previous || Next -> |