Cases reported "Fever"

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1/2. Shaking, chills, and rigors with once-daily gentamicin.

    A patient receiving once-daily gentamicin experienced shaking, chills, and rigors. This adverse reaction has occurred in patients around the country at many different institutions. Although the etiology is thought to be mediated by higher than normal endotoxin levels in one product, other possibilities must be explored.
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ranking = 1
keywords = endotoxin
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2/2. Humidifier fever and endotoxin exposure.

    Three cases of humidifier fever were detected in an office environment. Flavobacteria were found in the contaminated water in a humidifier. After an experimental exposure, the three persons with previous symptoms suffered from fever and slight respiratory symptoms. A leucocytosis and an increase in the number of segmented white blood cells were found the day following the exposure. General immunoglobulins as well as antibodies to flavobacterium and endotoxin were slightly elevated in the exposed group. The possibility that endotoxins may be the causative agent by means of an indirect complement activation is discussed.
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ranking = 6
keywords = endotoxin
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