Cases reported "Fibroma, Ossifying"

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1/46. Protuberant fibro-osseous lesions of the temporal bone: a unique clinicopathologic diagnosis.

    OBJECTIVE: The objective of the study was to describe the clinical presentation and treatment of exophytic fibro-osseous temporal bone lesions, a clinical entity never previously reported, and to consider the differential diagnosis. STUDY DESIGN: The design of the study was a retrospective case review. SETTING: The setting was a tertiary referral center. patients: Two patients diagnosed with exophytic fibro-osseous temporal bone lesions were included in the study. INTERVENTION: The intervention used was surgical excision. MAIN OUTCOME MEASURE: The main outcome measures were clinical, radiographic, and histopathologic examination. RESULTS: There was no evidence of recurrence at 15 and 17 months after surgery. CONCLUSION: Although fibro-osseous lesions of the temporal bone have been previously reported, there have been no reported cases of an exophytic variant.
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2/46. CT and MRI of congenital sinonasal ossifying fibroma.

    We report a 9-year-old boy with a sinonasal ossifying fibroma, probably congenital, with atypical findings on CT and MRI. CT revealed a soft-tissue density mass in the sphenoethmoidal sinuses, nasal cavity and right maxillary sinus with a few foci of calcification and with remodelling and destruction of the adjacent facial bones. MRI showed high signal on T2- and intermediate signal on T1-weighted images. A thin, partly enhancing outer shell and some nonenhancing septa were visible on contrast-enhanced images. MRI also showed the tumour to extend into the anterior cranial fossa. Subtotal removal was performed. We compare our findings with reports in the literature and discuss the differences from fibrous dysplasia.
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3/46. Ossifying fibromyxoid tumor of soft parts: clinicopathologic, immunohistochemical and ultrastructural study of four cases.

    Four cases of uncommon soft tissue tumors were investigated histopathologically. All of them consisted of fibrous and myxoid components, and mature bone showed shell-like characteristics. Histological features revealed these tumors were well circumscribed by a thick collagenous fibrous capsule and composed of uniform-sized fusiform cells with eosinophilic cytoplasm and a round or oval nucleus in the myxoid matrix. An incomplete shell of mature bone with lamellar structure was also observed at the periphery. Immunohistochemical and ultrastructural studies were performed. The major component of the proliferating cells in the tumors had positive staining for vimentin, S-100 protein, neuron-specific enolase and synaptophysin. The myxoid matrix was stained by alcian blue and was digested completely by pretreatment with hyaluronidase. Electron microscopy showed the cytoplasm contained dense-core granules measuring 100-200 nm and abundant filaments of an intermediate size. It is suggested that these uncommon tumors might be diagnosed as the 'ossifying fibromyxoid tumor of soft parts' previously described by Enzinger et al., which were derived from peripheral nerve sheath tumors such as neurofibroma and myxoid neurofibroma.
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4/46. Peripheral giant cell granuloma: a potentially aggressive lesion in children.

    A slowly enlarging gingival mass with a reddish-purple surface is observed in a school-age boy. The lesion was first noted 3 months ago during a routine oral examination but recently it has increased in size and interferes with eating. A periapical radiograph demonstrated focal loss of the alveolar crestal bone in the mandibular incisor region. The diagnosis of peripheral giant cell granuloma, a benign reactive gingival lesion, is confirmed by histopathologic examination. Early detection and excision of this hyperplastic nodule is important to minimize potential dentoalveolar complications.
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5/46. Juvenile ossifying fibroma of the mandible. An 8 year radiological follow-up.

    An 8-year follow-up of a juvenile ossifying fibroma in the left mandible of a 4-year-old boy is presented. The case demonstrated initial lack of radiological evidence of demarcation and subsequent eccentric enlargement, selective tooth displacement and a multilocular appearance in areas of active growth. An aneurysmal bone cyst and a decrease in the bone content was present in the excision specimen.
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6/46. Ossifying fibroma arising in the right ethmoid sinus and nasal cavity.

    Ossifying fibroma, a rare tumor entity, is a well-demarcated benign fibro-osseous tumor composed of bone, fibrous tissue and cementum. It is commonly found in the mandible, but also found in the maxilla and paranasal sinuses. Simple curettage is enough when the fibrous lesions are located in the mandible but a complete en bloc excision is required when these lesions are located in the maxilla and paransal sinuses to relieve symptoms and prevent recurrence. With the advent of sinonasal endoscopy in the mid 1980s, and subsequent advances in surgical techniques, endoscopic management of the fibrous-osseous lesions has become possible. In the current case study, we report a successful endoscopic removal of a huge ossifying fibroma located in the right ethmoid sinus and nasal cavity.
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keywords = bone
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7/46. Ossifying fibromyxoid tumor of soft parts: report of a case with novel cytogenetic findings.

    A slowly growing tumor of the left thenar region in a 40-year-old man had the classic features of an ossifying fibromyxoid tumor of soft parts, including an incomplete shell of lamellar bone; a center composed of nodular aggregates of small spindled, oval, and stellate cells in abundant myxoid stroma; and strong expression of vimentin, S-100, and neuron-specific enolase by the tumor cells. Clonal chromosomal abnormalities included loss of a chromosome 6, extra material of unknown origin attached to the long arm of chromosome 12, and an unbalanced translocation involving the short arm of a chromosome 6 and the long arm of a chromosome 14. The karyotype was interpreted as 45,XY, der(6;14)(p10;q10),add(12)(q24.3). The chromosomal abnormalities suggest osteochondroblastic rather than neuronal or schwannian lineage.
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ranking = 0.14285714285714
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8/46. Excision and repair of the peripheral ossifying fibroma: a report of 3 cases.

    BACKGROUND: The peripheral ossifying fibroma (POF), one of the most common gingival lesions, has a recurrence rate of nearly 20%. To minimize the reappearance of this lesion, it must be completely excised. In the maxillary anterior region, total excision of a POF can result in an unsightly gingival defect. methods: Three cases are presented in which a POF was excised from the gingiva facial to a maxillary central incisor. One of these lesions had previously undergone 2 cycles of conservative excision and recurrence. In all cases, the lesions were excised down to bone. Each of the resulting gingival defects was repaired by a distinct plastic surgery procedure, including a laterally positioned flap, a subepithelial connective tissue graft, and a coronally positioned flap. RESULTS: The defects resulting from the biopsies were satisfactorily repaired. The patients were followed over postsurgical intervals of 10 to 30 months. None of the lesions recurred. CONCLUSIONS: It is customary to manage POF by aggressive excisional biopsy. Several different surgical approaches may potentially be used to repair the resultant gingival defect and minimize patient esthetic concerns.
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ranking = 0.14285714285714
keywords = bone
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9/46. Peripheral ossifying fibroma. Report of a case and review of the literature.

    Peripheral ossifying fibroma, a reactive gingival disorder known under the generic term of epulis, is widely considered to originate from the cells of the periodontal ligament. A 39-year-old woman presented with a well circumscribed, hard pedunculated exophytic tumor measuring 2 cm in size, without ulceration. The lesion had developed three months before in the interdental space, between the lower left lateral incisor and canine. No radiological signs of involvement of the alveolar ridge were observed, and the clinically manifest diastema was confirmed. The histological study of the specimen after simple resection with a cold scalpel confirmed the diagnosis of peripheral ossifying fibroma. The patient posteriorly suffered three recurrences that were respectively treated via simple resection, carbon dioxide laser exeresis and finally wide resection including the periodontal ligament, periosteum and underlying bone. There have been no further recurrences following wide resection. In addition to presenting this new case of peripheral ossifying fibroma, the present study reviews the literature, comments on the predisposing factors and treatment options, and suggests the importance of this disorder in the differential diagnosis of gingival lesions.
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ranking = 0.14285714285714
keywords = bone
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10/46. Ossifying fibroma of the temporal bone.

    A rare case of ossifying fibroma of the temporal bone is presented. Fibro-osseous lesions are benign neoplasms but may show an aggressive behaviour when invading important anatomical structures. The lack of experience in the treatment of those tumours is reflected in the small relative literature. The purpose of this paper is to contribute to the few cases already reported.
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ranking = 0.71428571428571
keywords = bone
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