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1/57. Cutaneous malignant melanoma: Tabuk experience.

    Cutaneous melanoma (CM) has a rising morbidity and mortality in the western world but is rare in certain geographical areas including the middle east. The aim of this study is to define the pattern of CM in this environment over a period of about two decades. A review of associated histological reports, dermatology, plastic general surgical admissions and outpatient census statistic of the North West Military Hospital (N.W.A.F.H.) were carried out from January 1978 to June 1996. The clinico-therapeutic information from both the review case and newly discovered CM was then studied. The result shows that CM is probably rare in the Tabuk military environment and possibly has a low mortality among the affected individuals. The presence of only 2 cases of CM among 73,955 patients over about 20 years suggests that this neoplasm is rare in N.W.A.F.H. Surgery, with localised expert reconstruction, probably offers the best cure for uncomplicated CM in this area. It is suggested that the geographical environment, genetic attributes, custom, attitude, presence of white, painted, sun-reflecting buildings, traditional dress-code and behaviour of the indigenes probably contribute to the suppression of and protection against CM in Tabuk. It is recommended that regular, antimlanoma education awareness programmes among the indigenes and avoidance of sunbathing attitude of the expatriate community should be encouraged in order to maintain this suggested natural selection protection.
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ranking = 1
keywords = malignant melanoma, melanoma
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2/57. radiotherapy of acral lentiginous melanoma of the foot.

    Four previously unreported cases of acral lentiginous melanoma of the foot treated by radiation are reported. All patients, for a variety of reasons, were not suitable for complete surgical excision. Three large doses of radiation were employed using the 0, 7, 21 technique. Local response of the melanoma to radiotherapy was excellent and all patients were well palliated by the treatment. This treatment of acral lentiginous melanoma is recommended in patients with this diagnosis who, due to age, medical condition, or the presence of metastasis, are not suitable for standard treatment (surgery).
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ranking = 0.66713743515784
keywords = melanoma
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3/57. Malignant melanoma of the foot and ankle.

    Malignant melanoma is a serious and devastating skin disease that podiatrists may be called upon to treat. It is pertinent that delays in diagnosis and treatment of malignant melanoma be avoided. Some of the topics discussed in this article are causes, clinical features, classification, and treatment of malignant melanoma, focusing on the foot and ankle.
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ranking = 0.92887406545861
keywords = malignant melanoma, melanoma
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4/57. Metastatic malignant melanoma to the foot and ankle: a review of the literature and case report.

    The lower extremity is a frequent site for malignant melanomas. However, skeletal metastases involving the foot and ankle are a rarity. Nearly all documented cases of secondary pedal bone metastasis have originated from a primary subungual melanoma. The following case study illustrates an unusual skeletal metastasis to the foot and ankle arising from a primary malignant melanoma of the torso.
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ranking = 1.4523473260602
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)

5/57. Distal plantar area reconstruction using a flexor digitorum brevis muscle flap with reverse-flow lateral plantar artery.

    It is difficult to resurface skin defects of the sole because of its unique anatomy, which is resistant to mechanical stimuli. Though various methods have been reported, few are functionally satisfactory, and it is especially difficult to repair the distal plantar area. We report a reconstruction of the distal plantar area using a flexor digitorum brevis muscle flap based on a reverse-flow lateral plantar artery pedicle in a patient with a malignant melanoma on the right lateral metatarsal head of the fifth toe. The muscle flap was sufficient to cover the exposed fifth metatarsal and was covered with a full-thickness skin graft. The result was favourable and the patient has a normal gait and no pressure sores.
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ranking = 0.22617366303008
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)

6/57. Malignant melanoma of soft tissues (clear cell sarcoma) of the foot. Is MRI able to perform a specific diagnosis? Report of one case and review of the radiological literature.

    The magnetic resonance (MR) findings in malignant melanoma of soft tissues, also called clear cell sarcoma of tendons and aponeuroses, have been described as a focal abnormality with a specific MR pattern of increased signal intensity (relative to normal muscle) on T1 weighted sequences and variably decreased signal intensity on T2 weighted sequences (relative to surrounding fat). We have reported here a case of malignant melanoma of soft tissues of the foot, studied with ultrasonography (US) and MR, in which MR showed T1-hypointensity, T2-hyperintensity and marked gadolinium uptake. We have described the relationship between the intracytoplasmic melanin amount of and these atypical MR findings.
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ranking = 0.83356871757892
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)

7/57. Using computer graphics to preserve function in resection of malignant melanoma of the foot.

    The increasing incidence of malignant melanoma challenges physicians to find innovative ways to preserve function and appearance in affected areas that require partial resection. We carefully planned the resection of a malignant lesion between the third and fourth toes of a 77-year-old man with the aid of computer technology. The subsequent excision of the third, fourth, and fifth digits was executed such that the new metatarsal arc formed would approximate the dimensions of the optimal hyperbola, thereby minimizing gait disturbance.
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ranking = 1.1308683151504
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)

8/57. Acral lentiginous melanoma: case studies from Kauai.

    Cutaneous malignant is generally regarded as a skin cancer of Caucasians. However, one subtype, acral lentiginous melanoma (ALM), has an equal distribution among all ethnic groups and is the variant most common in non-Caucasians. In its early stage it is difficult to recognize and, unless diagnosed early, has a very poor prognosis. Herein, we present 3 cases of ALM seen on Kauai in 1990.
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ranking = 0.47652673939845
keywords = melanoma
(Clic here for more details about this article)

9/57. Invasive melanoma of the hallux.

    The authors present a classic case of superficial spreading melanoma. Superficial spreading melanoma is the most commonly acquired cutaneous malignant melanoma. Its true etiology is unknown. Superficial spreading melanoma may remain in the epidermis with peripheral extension (radial growth phase) for as long as 5 years before invading deeper tissue layers. Definitive diagnosis is established through biopsy. Treatment, following biopsy, involves wide radical excision, and possibly lymphadenectomy and combination chemotherapy depending on the extent of the pathology.
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ranking = 0.89331109818791
keywords = malignant melanoma, melanoma
(Clic here for more details about this article)

10/57. Eccrine poroma: a differential diagnosis in chronic foot lesions.

    Eccrine poroma is a benign tumor which arises from the intraepidermal portion of the eccrine sweat glands. It usually occurs as a solitary lesion in the extremity, with the foot and sole as a common site. It may present as a foot mass, ulcerative lesion, bleeding lesion, or suspected melanoma. The clinical diagnosis is often delayed or inaccurate. Three cases of eccrine poroma on the foot are presented. The clinical and histological features, problem in diagnosis, chance of recurrence, and potential transformation to eccrine porocarcinoma are discussed. It is emphasized that eccrine poroma should be considered in the differential diagnosis of chronic foot lesions. Complete excision prevents recurrence, excludes dysplastic change, and prevents future malignant change.
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ranking = 0.095305347879691
keywords = melanoma
(Clic here for more details about this article)
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