1/7. pregnancy following bromocryptine therapy for the amenorrhoea-galactorrhoea syndrome due to a pituitary tumour.A woman developed amenorrhoea and galactorrhoea after partial removal of a pituitary tumor during pregnancy. Hyperprolactinaemia was supressed by therapy with bromocryptine (CB 154, Sandoz) resulting in cessation of galactorrhoea in two months, spontaneous menstruation after eight months, and pregnancy after twelve months.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |
2/7. 13 trisomy born to a mother treated with bromocriptine: incidental or not?A case of 13 trisomy born to a mother treated with bromocriptine is described. She, 27 years old, was treated with bromocriptine (5 mg/day) as a galactorrhea amenorrhea syndrome with hyperprolactinemia (basal 34-122 ng/ml). After the treatment for about a month, disappearance of galactorrhea and occurrence of menstruation were observed. She became pregnant on the second ovulation. On the 34th week she got a male 13 trisomy (47, XY, 13) baby with premature delivery. The baby died 11 hr after his birth. After the first delivery, bromocriptine was readministered. Following the induced abortion on the second pregnancy, she borned a healthy baby on the third pregnancy in spite of taking bromocriptine. This case of 13 trisomy might be incidental. However, the effect of bromocriptine on chromosome should be further evaluated in detail.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |
3/7. The treatment with 2-brom-alfa ergocriptine in the syndrome amenorrhea-galactorrhea.In this study, the authors present the results obtained in thirteen cases with amenorrhea-galactorrhea treated with 2-brom-alfa-ergocriptine in which the menstruation has reoccurred in eleven patients, three of them becoming pregnant. The authors have accurately described the evolution of the three pregnancies, which were delivered at term and the children born were normal. The present study was elaborated in the Sterility Department of the Clinic of obstetrics and gynecology "Giulesti", University School of medicine, Bucharest. The study refers to the use of 2-brom-alfa-ergocriptine (Parlodel-Sandoz) in the treatment of the amenorrhea-galactorrhea syndrome associated with sterility.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |
4/7. amenorrhea-galactorrhea syndrome with craniopharyngioma.Two cases of craniopharyngioma presenting with amenorrhea-galactorrhea syndrome due to hyperprolactinemia are reported. After operation and irradiation, the tumor reduced markedly in size. Coincidental decrease in plasma prolactin level and restoration of menstruation seem to support the view that the hypothalamic prolactin inhibiting factor (PIF) had played an important role in hyperprolactinemia in these two patients.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |
5/7. pregnancy following combined therapy with thyroid hormone and bromocriptine in a patient with amenorrhea-galactorrhea due to primary hypothyroidism.Combined therapy with thyroid hormone (desiccated thyroid) and bromocriptine (CB-154) was applied in a 29-year-old patient with amenorrhea-galactorrhea due to primary hypothyroidism. Two months after commencing administration of desiccated thyroid, the elevated serum level of TSH returned to the normal range while that of PRL remained within the supranormal range (from 134 ng/ml to 86.7 ng/ml). However, it fell to the normal range 2 weeks after administration of CB-154 with thyroid hormone. Subsequently, the galactorrhea completely ceased and ovulatory menstruation resumed with 3 months, and conception was achieved directly after that menstrual period. Only desiccated thyroid was administered during pregnancy and the patient delivered a male infant weighing 2,800 g without difficulty.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |
6/7. Hyperprolactinaemia and infertility following cranial irradiation for brain tumours: successful treatment with bromocriptine.Two young women developed oligomenorrhoea and galactorrhoea 4 and 7 years after whole brain irradiation for brain tumours. Both had mild hyperprolactinaemia due to irradiation-induced hypothalamic damage. In both patients, oral bromocriptine normalized prolactin levels and menstruation resumed. One patient then had a successful pregnancy.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |
7/7. pregnancy following 2-bromo-alpha-ergocryptine (CB-154)-induced ovulation in an acromegalic patient with galactorrhea and amenorrhea.An acromegalic patient with galactorrhea-amenorrhea who conceived following long-term 2-bromo-alpha-ergocryptine (CB-154) therapy is described. During CB-154 therapy, determinations of serum prolactin (PRL), luteinizing hormone (LH)-human chorionic gonadotropin, follicle-stimulating hormone a reduction in PRL level followed by an LH peak, a rise in basal body temperature and menstruation. The patient became pregnant during the next cycle, but therapeutic abortion was performed because of the active acromegaly. These results demonstrate that CB-154 can restore ovulatory function not only to the patient with a hypothalamic disorder but also to the acromegalic patient with an enlarged sella turcica.- - - - - - - - - - ranking = 1keywords = menstruation (Clic here for more details about this article) |