Cases reported "Helicobacter Infections"

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1/7. helicobacter pylori eradication can induce platelet recovery in idiopathic thrombocytopenic purpura.

    Recent reports have suggested an association between helicobacter pylori infection and idiopathic thrombocytopenic purpura (ITP). The prevalence of H pylori infection and the effect of its eradication in a series of 30 ITP patients were investigated. H pylori infection has been documented in 13 patients (43.33%) by 13C urea breath test and confirmed by histologic examination. Bacterium eradication with antibiotics, obtained in 12 of 13 infected patients (92.3%), led to a complete response in 4 (33.33%) and to a partial response (platelets 90 x 10(9)/L-120 x 10(9)/L) in 2 (16.66%). The response was maintained for a median of 8.33 months, but 1 patient relapsed 7 months after eradication. Search for H pylori infection seems appropriate in ITP patients at diagnosis. Bacterium eradication provides a new good option for a nonimmunosuppressive treatment in some ITP patients.
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ranking = 1
keywords = thrombocytopenic, purpura
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2/7. Thrombocytopenic purpura: an unusual complication of eradication therapy for helicobacter pylori.

    A case of severe thrombocytopenic purpura is described in a 56-year-old female following helicobacter pylori eradication therapy consisting of omeprazole, clarithromycin and amoxycillin. The pathogenesis of this patient's thrombocytopenia appears to be quite complex. Whilst it was clearly triggered by antibiotic treatment, a direct toxic mechanism does not provide an adequate explanation for the severity and lack of responsiveness to drug treatment. It is tempting to suggest that an immunological mechanism and splenomegaly were also involved.
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ranking = 0.52353926695394
keywords = thrombocytopenic, purpura
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3/7. Complete platelet recovery after treatment of helicobacter pylori infection in a child with chronic immune thrombocytopenic purpura: a case report.

    helicobacter pylori gastritis has been associated with autoimmune disease, including immune thrombocytopenic purpura (ITP). The most recent reports also have supported this association in adults. ITP in children differs from that in adults in terms of clinical picture and mechanisms of thrombocytopenia. The authors report a case of a 12-year-old boy with chronic ITP, in whom they detected H. pylori infection and observed a complete platelet recovery after the eradication of H. pylori.
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ranking = 1
keywords = thrombocytopenic, purpura
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4/7. helicobacter pylori infection in children with chronic idiopathic thrombocytopenic purpura.

    BACKGROUND: Recently a high prevalence of helicobacter pylori infection has been reported in adult patients with chronic idiopathic thrombocytopenic purpura (cITP). Furthermore, after H. pylori eradication therapy in such patients, their platelet counts have been observed to increase, suggesting that H. pylori may be a causative agent of adult cITP. However, there have been only a few reports of children with cITP. The purpose of the present paper was to examine the association between H. pylori infection and cITP in Japanese children. methods: helicobacter pylori stool antigens (HpSA) were measured and the prevalence of H. pylori infection was determined in 10 children with cITP. RESULTS: helicobacter pylori infection was found in only two of the subjects. In a boy, the urea breath test (UBT) was also positive and the patient received eradication therapy using amoxicillin, clarithromycin, and lansoprazole for 1 week. The therapy was successful and the patient's platelet count increased. The response was maintained throughout more than 1 year of follow up. CONCLUSIONS: The prevalence of H. pylori infection in children with cITP is not high. However, the platelet count increased after eradication therapy in a boy with cITP. It is suggested that the eradication of H. pylori infection would be valuable in children, as well as in adults, with cITP.
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ranking = 1
keywords = thrombocytopenic, purpura
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5/7. Schonlein-Henoch purpura associated with gastric helicobacter pylori infection.

    Schonlein-Henoch purpura is characterized by palpable purpura, colicky abdominal pain, gastrointestinal hemorrhage, arthralgias, and renal involvement. Bacterial and viral infections, as well as drugs and diseases associated with immune complexes, are thought to be responsible. We describe the case of a 21-year-old woman with Schonlein-Henoch purpura and chronic active gastritis with erosions. helicobacter pylori was found in gastric mucosa using the newly introduced, nontoxic, noninvasive 13C-urea breath test; infection was confirmed by gastric mucosal biopsy. After eradication of H. pylori with omeprazole and amoxicillin, the skin changes, gastric complaints, and proteinuria disappeared. Ten months later, Schonlein-Henoch purpura recurred. H. pylori was again detected. After therapy, H. pylori was eradicated and the clinical manifestations faded. To our knowledge, H. pylori has not previously been described as a cause of Schonlein-Henoch purpura.
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ranking = 0.72796335064637
keywords = purpura
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6/7. Schonlein-Henoch vasculitis and chronic helicobacter pylori associated gastritis and duodenal ulcer: a case report.

    We describe the case of a child with Schonlein-Henoch purpura (SHP), bleeding duodenal ulcer and helicobacter pylori (H. pylori) associated gastritis. 5-year-old girl was hospitalized with typical symptoms of SHP. On the third day, the child has several episodes of hematemesis with bright red blood, accompanied by increased pain of the epigastric region. Gastroduodenal endoscopy revealed signs of atrophic gastritis in the antrum, duodenitis with diffuse petechiae, small erosions and bleeding ulcer. The gastric biopsy showed a moderately severe chronic gastritis with activity and H. pylori was detected. The therapy with ranitidine, metronidazole and amoxycillin was introduced for a period of 30 days. At follow-up 2 months later, clinical examination and routine laboratory tests were normal. A repeated endoscopy revealed no evidence of lesions and H. pylori negative gastric biopsy. In our case, the associated chronic antral gastritis and H. pylori infection may well have aggravated the gastrointestinal symptoms of SHP. We feel it would be useful to check for H. pylori in patients with gastrointestinal manifestations of SHP, such as bleeding and important epigastric pain.
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ranking = 0.080884816738485
keywords = purpura
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7/7. Schonlein-Henoch purpura in association with duodenal ulcer and gastric helicobacter pylori infection.

    We report a 62-year-old man who presented with Schonlein-Henoch purpura (SHP) associated with duodenal ulcer and gastric helicobacter pylori (HP) infection. The recurrent purpuric rash faded after HP eradication with amoxycillin, clarythromycin, and omeprazole treatment. These findings suggest a causative role for HP in the occurrence of SHP.
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ranking = 0.40442408369243
keywords = purpura
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