Cases reported "Hepatitis, Viral, Human"

Filter by keywords:



Filtering documents. Please wait...

21/61. Fulminant varicella hepatitis in a human immunodeficiency virus infected patient: case report and review of the literature.

    We report the case of a 35-y-old hiv-infected female, who presented fulminant varicella hepatitis and recovered under medical treatment. Varicella zoster virus is an uncommon cause of acute liver disease which occurs mainly in immunocompromised patients. acyclovir is the cornerstone of the treatment.
- - - - - - - - - -
ranking = 1
keywords = varicella, zoster
(Clic here for more details about this article)

22/61. Severe herpes simplex virus hepatitis following autologous bone marrow transplantation: successful treatment with high dose intravenous acyclovir.

    A 17-year-old male patient with T-cell type lymphoblastic lymphoma in complete remission underwent high dose chemotherapy (busulfan 16 mg/kg and cyclophosphamide 120 mg/kg) followed by autologous bone marrow transplantation (ABMT). The patient had been taking oral acyclovir (200 mg x 5) daily from seven days prior to the ABMT (day -7). On day 24, he complained of epigastralgia and general malaise, and the next day his GOT and GPT rose to 570 U/l and 397 U/l, respectively. Although he had no mucocutaneous lesions, hepatitis caused by a herpes virus was suspected, and high dose intravenous acyclovir (10 mg/kg x 3/day) was immediately started. His GOT, GPT and total bilirubin reached peaks of 2,870 U/l on day 26, 1,830 U/l on day 27 and 10.3 mg/dl on day 39, respectively, and rapidly improved thereafter. Serological analyses on IgG antibody titers to herpes simplex virus type 1 using an enzyme-linked immunosorbent assay revealed specific increases (454-fold before transplantation to 3,830-fold on day 46). Antiviral antibody titers to cytomegalovirus, varicella-zoster virus and Epstein-Barr virus showed no significant changes. The serologic markers of hepatitis b virus, hepatitis a virus and hepatitis c virus were all negative. The results indicate the patient's severe icteric hepatitis to have been caused by a reactivation of herpes simplex virus type 1 due to immunosuppression after high dose chemotherapy with ABMT. It is suggested that prompt commencement of high dose intravenous acyclovir is required to treat severe herpes simplex virus hepatitis affecting immunocompromised patients.
- - - - - - - - - -
ranking = 2.8686669667263
keywords = herpes, varicella, zoster
(Clic here for more details about this article)

23/61. herpes simplex virus hepatitis in pregnancy. Two patients successfully treated with acyclovir.

    Two cases of herpes simplex virus hepatitis in pregnancy are presented. Each case was characterized by extremely high serum aminotransferase levels with minimal bilirubin elevation. In both cases, liver biopsy was instrumental in arriving at the diagnosis. In addition, computed tomography showed a radiographic appearance of the liver not characteristically seen in other hepatic disorders of pregnancy. A high index of suspicion in the second case led to early recognition and treatment. Despite the presence of fulminant liver failure and evidence of herpes encephalitis in the other case, institution of therapy with acyclovir was associated with complete recovery in both patients. The present cases are compared and contrasted with the literature. The incidence of two cases within a 6-month period suggests that herpes simplex virus hepatitis in pregnancy may occur more frequently than previously reported.
- - - - - - - - - -
ranking = 1.0132969793222
keywords = herpes, encephalitis
(Clic here for more details about this article)

24/61. Three cases of neonatal herpes simplex virus infection presenting as fulminant hepatitis.

    We report three cases of neonatal herpes simplex virus (HSV) infection presenting as fulminant hepatitis. None of the patients had clear risk factors for HSV infection and they all died. Antiviral treatment for HSV is currently available but must be administered early in the course of the disease before irreversible liver tissue damage is present. Since the diagnosis may be difficult to establish, we wish to draw the attention of clinicians to the presentation of neonatal HSV infection and suggest that in such cases viral cultures, including culture of liver tissue, should be obtained early and antiviral treatment administered while awaiting the culture results.
- - - - - - - - - -
ranking = 1.6621616947961
keywords = herpes
(Clic here for more details about this article)

25/61. Lethal herpes simplex virus type 1 hepatitis in a normal adult.

    A fatal case of human herpes simplex type 1 hepatitis is presented and compared with cases previously reported. The patient presented with fulminant hepatic necrosis, coagulopathy, leukopenia, thrombocytopenia, and absence of typical herpetic mucocutaneous lesions. Liver biopsy helped to establish a presumptive diagnosis in this patient and in one previously reported case. Theoretically, early diagnosis might enable application of specific antiviral therapy in future cases of this usually fatal infection.
- - - - - - - - - -
ranking = 1.6621616947961
keywords = herpes
(Clic here for more details about this article)

26/61. Fatal varicella in a healthy girl.

    A fatal case of chickenpox in a healthy 6-year-old girl is reported. She presented with hemorrhagic bullae from thrombocytopenia and then progressed rapidly to disseminated infection involving many systems causing myocarditis, pneumonitis and hepatitis. A peculiar blood picture with marked leukocytosis (leukemoid reaction) is revised and discussed.
- - - - - - - - - -
ranking = 0.79079174494746
keywords = varicella
(Clic here for more details about this article)

27/61. Adult respiratory distress syndrome secondary to varicella infection in a young adult.

    A case is described of chickenpox in a young non-immunosuppressed adult, resulting in adult respiratory distress syndrome and hepatitis, which was successfully managed with artificial ventilation and vidarabine.
- - - - - - - - - -
ranking = 0.79079174494746
keywords = varicella
(Clic here for more details about this article)

28/61. Disseminated herpes simplex virus infection in an apparently immunocompetent woman.

    A young, previously healthy woman developed bilateral exudative tonsillitis that was associated with severe systemic symptoms. This was followed by evidence of multisystem disease with acute abdominal pain, raised liver enzyme levels, respiratory difficulty, increasing drowsiness and multiple vesicular skin lesions. herpes simplex virus type-1 was isolated from skin lesions and a throat swab and herpes simplex virus type-1 antigen was detected in a liver biopsy sample. She recovered rapidly without any sequelae after treatment with intravenously administered acyclovir.
- - - - - - - - - -
ranking = 1.6621616947961
keywords = herpes
(Clic here for more details about this article)

29/61. Varicella-zoster virus infections in children infected with human immunodeficiency virus.

    Primary varicella-zoster (VZ) infection in eight children with perinatally acquired human immunodeficiency virus infection tended to be severe, prolonged, complicated by bacterial infections and in one case fatal. Depletion of CD4-lymphocytes was associated with chronic and recurrent VZ infection. In some patients convalescent VZ antibody titers were low and did not correlate with recurrence of VZ lesions. Administration of acyclovir appeared to be beneficial in suppressing VZ in human immunodeficiency virus-infected children with primary or recurrent VZ infection.
- - - - - - - - - -
ranking = 0.25524953031526
keywords = varicella, zoster
(Clic here for more details about this article)

30/61. Recovery from herpes simplex virus type-1 hepatitis in a female adult.

    A study of one case of herpes simplex hepatitis in an adult woman is presented. The clinical feature and laboratory findings were typical for acute hepatitis in a febrile patient without herpetic mucocutaneous lesions. The evidence of high IgM antibody titer in serum against herpes simplex virus and confirmation of the herpes simplex virus hepatitis by immunofluorescent microscopy after liver biopsy helped us establish the diagnosis. After 3-months the patient recovered.
- - - - - - - - - -
ranking = 2.3270263727145
keywords = herpes
(Clic here for more details about this article)
<- Previous || Next ->


Leave a message about 'Hepatitis, Viral, Human'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.