1/5. Anatomic evidence of spontaneous intrauterine closure of a ventricular septal defect.An infant, born to a mother on carbamazepine monotherapy, had a complex cardiac anomaly, consisting of double-outlet right ventricle (DORV), right-sided aorta, pulmonary artery hypoplasia, left ventricular endocardial fibroelastosis, and anatomic evidence of a spontaneously closed muscular ventricular septal defect (VSD). The last finding is one which, to the best of our knowledge, has never been illustrated before.- - - - - - - - - - ranking = 1keywords = artery (Clic here for more details about this article) |
2/5. Diamniotic placentation associated with omphalopagus conjoined twins: implications for a contemporary model of conjoined twinning.We have studied omphalopagus conjoined twins with a diamniotic monochorionic placenta. Although conjoined twins usually present in a single amniotic sac, one other example of diamniotic placenta has been reported in omphalopagus twins [Weston et al., 1990: Am J Med Genet 37:558-561]. Most theories concerning the pathogenesis of conjoined twinning exclude the possibility of diamniotic placentation. However, Spencer [1992: teratology 45:591-602] recently elaborated a model for conjoined twinning based on duplication of organizing centers (primitive streaks) during gastrulation. We have considered the fate of embryonic membranes according to this model of omphalopagus twinning and show that diamniotic placentation is a predictable outcome.- - - - - - - - - - ranking = 0.51494819361647keywords = single (Clic here for more details about this article) |
3/5. Morphology of pulmonary extralobar sequestration in neonatal death by hyaline membrane disease.We present an unusual case of extralobar pulmonary sequestration associated with hyaline membrane disease (HMD) that caused the death of a premature baby in the first day of life. The sequestered parenchyma was nourished by an aberrant aortic vessel. Notable was the presence of typical HMD in all the lung parenchyma perfused by the pulmonary artery; the sequestered lung tissue presented a dysplastic structure compatible with CCAM. A few similar cases have been found in the literature. In all of the reported cases there are morphologic aspects characteristic of HMD in the portions normally receiving blood from the pulmonary artery. These findings suggest the importance of the blood pulmonary circulation in the pathogenesis of HMD, whose exact causes are not fully known.- - - - - - - - - - ranking = 2keywords = artery (Clic here for more details about this article) |
4/5. Unusual uterine malformation. Double cervix with single corpus and single vagina.An unusual uterine malformation in which double cervix was the sole mullerian tube fusion defect is presented. It was associated with numerous other congenital anomalies in a 4-month-old infant with normal chromosome studies. The embryologic significance of this defective fusion is discussed.- - - - - - - - - - ranking = 4.1195855489318keywords = single (Clic here for more details about this article) |
5/5. Microvascular and thrombolytic revascularization of an arm in a 32-week-gestation neonate: case report and review of the literature.A 2300-g pre-term neonate with severe hyaline membrane disease experienced right forearm and hand ischemia following a brachial arterial line insertion. limb salvage was achieved through combined microsurgical exploration and thrombectomy of the brachial and radial arteries, with postoperative regional infusion of tissue plasminogen activator (TPA) through the distal radial artery for 48 hr, to dissolve a thrombus within the small vessels of the hand. This report advocates combined surgical and regional thrombolytic therapy with tissue plasminogen activator as management for neonatal arterial thrombosis and limb ischemia.- - - - - - - - - - ranking = 1keywords = artery (Clic here for more details about this article) |