Cases reported "Hydatidiform Mole"

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1/7. Early prenatal sonographic diagnosis of twin triploid gestation presenting with fetal hydrops and theca-lutein ovarian cysts.

    The presence of theca-lutein ovarian cysts in the early second trimester of pregnancy is highly suspicious for a complete hydatidiform molar pregnancy but can be seen in association with a partial mole. Theca-lutein cysts may occur following hormonal stimulation for assisted reproductive techniques or in association with multiple gestations. Rare causes include immune and nonimmune fetal hydrops, maternal hypothyroidism, and triploid gestations. We report a case of a monochorionic twin gestation in which prenatal sonography demonstrated multiple anomalies and hydrops in each twin and bilateral theca-lutein ovarian cysts. triploidy in both twins and a partial hydatidiform mole were confirmed at pathologic examination.
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keywords = lutein
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2/7. Criteria of complete remission from trophoblastic neoplasia with the use of human chorionic gonadotropin (HCG) excretion pattern as a parameter.

    The excretion pattern of human chorionic gonadotropin (hCG) or luteinizing hormone (LH) was observed in the urine of 77 patients with trophoblastic neoplasia, 109 with complete remission from trophoblastic neoplasia, and 94 with no trophoblastic neoplasia, when the anti-beta-subunit hCG system radioimmunoassay (anti-beta-subunit RIA), which specifically measured hCG was used. The sensitivity of anti-beta-subunit RIA was limited to urinary hCG 16 mIL/ml from the specificity of the anti-beta-subunit serum. luteinizing hormone in the urine of patients with complete remission and in normal menstrual, postmenopausal, and castrated women was less than 16 mIU/ml in most cases. The excretion pattern of urinary hCG in the patients undergoing treatment for trophoblastic neoplasia was more clearly comprehended with the anti-beta-subunit RIA as compared with the anti-hCH RIA. The criteria for judgment of complete remission were that the hCG value dropped to less than 16 mIU/ml and that cellular response was not observed at least in the last two courses.
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ranking = 0.14285714285714
keywords = lutein
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3/7. Theca lutein ovarian cyst may be pathognomonic for trophoblastic neoplasia.

    Two cases are presented in which theca lutein tissue was found at the time of indicated pelvic surgery performed long after treatment for hydatidiform mole. This indicator for the presence of trophoblastic tissue was not recognized, and clinical metastatic gestational trophoblastic neoplasia subsequently developed in each patient. Theca lutein tissue found at pelvic surgery merits investigation by beta-human chorionic gonadotropin radioimmunoassay and is likely to be associated with subclinical latent trophoblastic neoplasia.
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ranking = 0.85714285714286
keywords = lutein
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4/7. Delayed regression of huge theca lutein cysts monitored by serial sonograms and beta-HCG levels.

    The important role of serum beta-human chorionic gonadotropin (beta-HCG) in detecting spread of trophoblastic disease following evacuation of a hydatidiform mole is well established (1,2). Although sonography is accepted as the primary imaging technique in the diagnosis of hydatidiform mole (3), only a few authors have described the post-evacuation appearances of the pelvis, in particular the regression of theca lutein cysts (4,5). We here report a patient in whom there was delayed regression of huge theca lutein cysts compared to the regression of the serum beta-HCG levels after evacuation of a benign non-recurring hydatidiform mole.
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ranking = 0.85714285714286
keywords = lutein
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5/7. Elevated titers of the beta subunit of human chorionic gonadotropin in oophorectomized women being treated for trophoblastic disease.

    radioimmunoassay has shown a cross-reaction of the beta subunit of human chorionic gonadotropin (HCG) with high levels of luteinizing hormone (LH) in the serum of four women who underwent bilateral oophorectomy as part of their treatment for trophoblastic disease. Administration of oral contraceptives led to suppression of the LH and beta subunit HCG titers.
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ranking = 0.14285714285714
keywords = lutein
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6/7. Massive hydronephrosis mimicking theca lutein cysts in association with partial hydatidiform mole.

    We present an unusual case of partial hydatidiform mole in which extensive, multiple cystic structures encompassing the entire right abdomen and pelvis, initially thought to represent theca lutein cysts, were subsequently shown to consist of massive unilateral right hydronephrosis. Percutaneous nephrostomy decompression bypassing the ureteropelvic obstruction revealed functional renal parenchyma.
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ranking = 0.71428571428571
keywords = lutein
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7/7. Steroid profiles in hydatidiform mole associated with theca-lutein cysts.

    Neutral steroids in urine were determined quantitatively with gaschromatography on capillary columns in a case of benign hydatidiform mole associated with bilateral theca-lutein cysts. A remarkable finding was the very high levels of 17-hydroxypregnanolone and pregnanetriol, which continued to rise until the 15th day after molar evacuation.
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ranking = 0.71428571428571
keywords = lutein
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