Cases reported "Hypernatremia"

Filter by keywords:



Filtering documents. Please wait...

1/3. hypokalemia and alkalosis in adipsic hypernatremia are not associated with hyperaldosteronism.

    Idiopathic adipsic hypernatremia (AH) is a rare disorder associated with hypokalemia and alkalosis. Hypokalemic alkalosis has been presumed to be secondary to hyperaldosteronism. We evaluated plasma renin activity, serum aldosterone, serum and urine electrolytes in a 17-year-old patient with AH on several occasions. Despite evidence of mild dehydration, serum Na >160 and K <3.2, aldosterone levels were suppressed and plasma renin activity was not elevated. urine Na and K were not conserved. We also examined electrolyte and hormone levels in previously reported cases of AH. aldosterone levels were not increased in any of the cases when measured. renin secretion was increased in 2 patients. Among the compiled cases serum K was inversely correlated with serum Na (r = -0.73, p < 0.002, n = 15). hypokalemia and alkalosis occurring in AH are not associated with secondary hyperaldosteronism. patients with AH may have chronic renal losses of potassium leading to hypokalemia and alkalosis.
- - - - - - - - - -
ranking = 1
keywords = hyperaldosteronism
(Clic here for more details about this article)

2/3. Idiopathic hyperaldosteronism in a dog.

    Idiopathic hyperaldosteronism was diagnosed in an 8-year-old castrated male Yorkshire Terrier, based on increased concentration of plasma aldosterone, hypertension, hypernatremia, decreased natriuresis, hypokalemia, and hyperkaluria. Unilateral adrenalectomy was performed after visualization of a nodule on the right adrenal gland. hyperplasia of the zona glomerulosa and increased postoperative aldosterone concentrations supported the diagnosis of idiopathic hyperaldosteronism.
- - - - - - - - - -
ranking = 1
keywords = hyperaldosteronism
(Clic here for more details about this article)

3/3. Paraneoplastic hypokalemia in acute myeloid leukemia: a case of renin activity in AML blast cells.

    hypokalemia due to renal potassium loss has frequently been observed in patients with acute myeloid leukemia (AML). The pathogenic mechanism for this hyperkaluresis is unclear. In this report we describe a patient with AML FAB M4, in whom the clinical course, the electrolyte disturbances, the serum aldosterone levels, and the diffuse hyperplasia of the adrenal cortex documented a typical case of marked secondary hyperaldosteronism. On analysis of the leukemic cells of this patient compared with normal bone marrow cells, a significant increase of renin-like activity in the cytosol of the blast cells was noted. Activation of the renin-angiotensin-aldosterone system by paraneoplastic production of renin-like activity in AML blast cells might contribute to the hypokalemia often observed in patients with acute myeloid leukemia.
- - - - - - - - - -
ranking = 0.16666666666667
keywords = hyperaldosteronism
(Clic here for more details about this article)


Leave a message about 'Hypernatremia'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.