Cases reported "Hypersensitivity, Delayed"

Filter by keywords:



Filtering documents. Please wait...

11/25. Delayed anaphylactoid reaction in a worker exposed to chromium.

    A 29-year-old male welder reported systemic reactions after exposure to chromium. inhalation challenge testing to 29 micrograms/m3 of sodium chromate aerosol resulted in late appearing systemic urticaria, angioedema, and severe bronchospasm that occurred at the same time as a threefold rise in plasma histamine. A direct leukocyte inhibitory factor test to 5.5 X 10(-6)mol/L Na2CrO4 was positive. Although the mechanism of this reaction is unknown, the positive leukocyte inhibitory factor and the general acceptance of hexavalent chromium as a contact skin sensitizer suggest that cell-mediated mechanisms could be involved.
- - - - - - - - - -
ranking = 1
keywords = exposure
(Clic here for more details about this article)

12/25. Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS.

    A patient with acquired immunodeficiency syndrome (AIDS) developed rash, fever, neutropenia, and elevated liver function tests during an initial course of trimethoprim-sulfamethoxazole (TMP-SMX) therapy. Upon reexposure to the drug, the patient experienced a severe anaphylactoid reaction associated with pulmonary edema and rhabdomyolysis. Reactions associated with TMP-SMX rechallenge in this patient population have been previously reported but have not been associated with this degree of severity. TMP-SMX therapy should be instituted with extreme caution in patients with AIDS who have demonstrated a prior hypersensitivity reaction to the drug.
- - - - - - - - - -
ranking = 1
keywords = exposure
(Clic here for more details about this article)

13/25. Generalized eruption with severe liver dysfunction associated with occupational exposure to trichloroethylene.

    Generalized dermatitis due to trichloroethylene is rare. A 21-year-old printer developed exfoliative dermatitis with mucous membrane involvement, fever and liver dysfunction after a 2-week occupational exposure to trichloroethylene. Positive patch-test reactions to trichloroethylene and to one of its metabolites, trichloroethanol, were observed. This dermatitis is considered to be mediated by a delayed-type hypersensitivity mechanism.
- - - - - - - - - -
ranking = 2400.6588513633
keywords = occupational exposure, exposure
(Clic here for more details about this article)

14/25. The late asthmatic response.

    Since LARs are associated with increases in airways reactivity, their significance may go well beyond the increase in symptoms due just to the allergen exposure. This is especially true since the increase in non-specific airways reactivity can last for weeks after a single exposure to allergen. Every effort should be made to search for possible allergic triggers in patients suspected to have LARs. Careful attention to historical information and skin test reactivity are critical in this evaluation. In situations where this approach is not revealing and where serious concerns remain about potential environmental triggers, a bronchial challenge to the suspected antigen can be considered. Since the nonspecific airways reactivity in patients with LAR may possibly be due to inflammation in the airways, the potential risk of transient induction of airways inflammation must be carefully weighed against the value of information that can be obtained from this procedure. Bronchial challenge should be performed only in an inpatient setting by experienced personnel under the supervision of a physician. A full explanation of the potential risks and benefits of this type of evaluation must be given to the patient and family. Treatment is primarily directed at allergen avoidance with use of a prophylactic drug, such as cromolyn sodium, when allergen avoidance is not possible.
- - - - - - - - - -
ranking = 2
keywords = exposure
(Clic here for more details about this article)

15/25. Immediate and late onset asthma from occupational exposure to soybean dust.

    Most patients sensitive to soybean experience gastrointentinal symptoms, urticaria, angioedema, and asthma after ingestion. However, we report here a previously non-allergic patient who developed immediate and late onset asthma after breathing soybean flour used in the manufacture of food supplements. She exhibited positive immediate and late skin test sensitivity as well as a positive bronchial challenge to a soybean flour extract. In contrast to another patient with an anaphylactic response after soybean ingestion, the radioallergosorbent test (RAST) to soybean antigen was negative in our patient.
- - - - - - - - - -
ranking = 1920.5270810906
keywords = occupational exposure, exposure
(Clic here for more details about this article)

16/25. Tetraethylene glycol diacrylate. A cause of delayed cutaneous irritant reaction and allergic contact dermatitis.

    A woman who worked as a materials handler in a plant manufacturing acrylated chemicals developed allergic contact allergy to tetraethylene glycol diacrylate (TTEGDA). Four co-workers experienced skin irritation 12 to 36 hours after skin contact with TTEGDA but had no immediate reaction at the time of exposure. The chemical sensitized the albino guinea pig in the guinea pig maximization test. By varying parameters such as the administration of Freund's complete adjuvent, the intradermal concentration injected for induction, and the diluent used for the injections, it was possible to alter the apparent sensitization potential of TTEGDA.
- - - - - - - - - -
ranking = 1
keywords = exposure
(Clic here for more details about this article)

17/25. asthma due to dust from redwood (sequoia sempervirens).

    An atopic patient with adult onset of asthma due to sawdust from redwood (sequoia sempervirens) is described. Specific late asthmatic reaction developed after challenge with inhalation of his own redwood sawdust. No subjective or objective immediate reactions were detected. Avoidance of exposure resulted in improvement. There were no pulmonary or systemic responses to challenge with inhalation of sawdust from pine wood.
- - - - - - - - - -
ranking = 1
keywords = exposure
(Clic here for more details about this article)

18/25. Occupational asthma due to pepsin.

    A 30-year-old atopic worker exposed to pepsin powder, herb, and pollen extracts at work developed an increase in asthmatic symptoms. Monitoring of peak expiratory flow rate revealed more important fluctuations at work. skin prick tests yielded a large immediate reaction to pepsin. Specific inhalation challenges confirmed the diagnosis; an intense early response was documented after exposure to pepsin. The pepsin IgE RAST was positive and selectively inhibited by pepsin.
- - - - - - - - - -
ranking = 1
keywords = exposure
(Clic here for more details about this article)

19/25. bronchoalveolar lavage in a patient with chronic berylliosis: evidence for hypersensitivity pneumonitis.

    Because immunologic mechanisms are thought to have a role in chronic berylliosis, we studied the immunologic properties of peripheral blood and bronchoalveolar lymphocytes in a patient with this disease. Although the percent of peripheral blood T cells was slightly reduced compared with that in controls (59% versus 70%), there was a large increase in the number and proportion (94% versus 62%) of bronchoalveolar T cells. The percent of activated bronchoalveolar T cells was nearly five times the control value (64.5% versus 14%). Both peripheral blood and bronchoalveolar lymphocytes proliferated in response to BeSO4 and BeF2 exposure but the response of bronchoalveolar lymphocytes was greater than comparable numbers of peripheral blood lymphocytes. These findings are consistent with the concept that chronic berylliosis is a form of hypersensitivity pneumonitis and that bronchoalveolar lavage may be helpful in establishing the diagnosis of this disease.
- - - - - - - - - -
ranking = 1
keywords = exposure
(Clic here for more details about this article)

20/25. Immediate and delayed onset "skip area" dermatitis presumed secondary to topical phenol exposure.

    A 21-year-old man was in brief accidental skin contact with epoxy resin stripper containing 10% phenol. He developed a painful, superficial necrotic eruption which slowly extended proximally without any further contact with the chemical, leaving skip areas of normal skin. About 3 and 7 months later he reported spontaneous flares within the area of original contact. Gradual release from an initially formed phenol-protein complex is thought to be responsible for the progression beyond the contact area and the delayed reaction.
- - - - - - - - - -
ranking = 4
keywords = exposure
(Clic here for more details about this article)
<- Previous || Next ->


Leave a message about 'Hypersensitivity, Delayed'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.