Cases reported "Hypersensitivity"

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1/2. Rapid loss of alveolar bone associated with nonprecious alloy crowns in two patients with nickel hypersensitivity.

    In recent years there has been a dramatic increase in the use of nonprecious alloy and porcelain crowns in clinical dentistry. The alloy in these restorations frequently contains a high percentage (greater than 70%) of nickel. Most cases of metal hypersensitivity are related to nickel, and clinical manifestations of the hypersensitivity are the result of a cellular (T lymphocyte) immune response. In this report, we review the cases of two women who demonstrated significant loss of alveolar bone about nickel-rich nonprecious alloy and porcelain crowns. The loss of alveolar bone occurred within 18 months after placement of the restorations. Both individuals displayed a positive patch test to a nickel preparation. These findings suggest that a Type IV hypersensitivity reaction may have accounted for the rapid loss of alveolar bone. Though the majority of individuals treated with nonprecious alloy and porcelain crowns apparently tolerate these restorations quite well, greater care is urged in case selection.
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ranking = 1
keywords = dentistry
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2/2. Metal allergy in dentistry: detection of allergen metals with X-ray fluorescence spectroscope and its application toward allergen elimination.

    Numerous metal allergies possibly resulting from intraoral metal restorations have been reported, although the mechanism of onset is not yet completely understood. Allergen elimination may be the most effective treatment, and location of allergen metal becomes essential. The x-ray fluorescence spectroscope was used to detect the allergen metals in intraoral metal restorations and personal and household items of metal allergy patients. The apparatus was evaluated preceding its clinical application, and restorations and personal items for 381 patients were analyzed to detect allergens. Successful diagnoses and allergen elimination treatment of three patients are reported.
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ranking = 4
keywords = dentistry
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