Cases reported "Iatrogenic Disease"

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1/5. Iatrogenic choroidal neovascularization occurring in patients undergoing macular surgery.

    PURPOSE: To report three cases of choroidal neovascularization (CNV) that occurred following surgical disruption of bruch membrane during macular surgery. methods: A retrospective case series was compiled. Macular translocation surgery with punctate retinotomy was performed in two patients for subfoveal CNV, and pars plana vitrectomy with epiretinal membrane (ERM) peeling was performed in one patient for idiopathic ERM. RESULTS: CNV developed at a site of subretinal cannulation in two cases of macular translocation, and at a site of inadvertent injury to bruch membrane with a vitreoretinal pick in the one case that underwent ERM peeling. CONCLUSIONS: These cases underscore the need to monitor breaks in bruch membrane for CNV following macular surgery.
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ranking = 1
keywords = neovascularization
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2/5. Photodynamic therapy with verteporfin in laser-induced choroidal neovascularization.

    PURPOSE: To report a case of laser-induced choroidal neovascularization (CNV) treated with verteporfin photodynamic therapy. DESIGN: Interventional case report. methods: A patient developed CNV in the macular area of the left eye 2 years following grid laser for macular edema secondary to branch retinal vein occlusion. RESULTS: The CNV was controlled with one session of photodynamic therapy. Lesion decreased in size, contracting to a smaller subretinal fibrotic scar. Vision improved from 20/200 to 20/100, and there was no recurrence at 2-year follow-up. No complications were encountered. CONCLUSION: Laser-induced CNV can be safely and effectively treated by photodynamic therapy.
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ranking = 1
keywords = neovascularization
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3/5. Iatrogenic choroidal neovascularization in sickle cell retinopathy.

    Fifteen patients (16 eyes) with proliferative sickle retinopathy treated with argon or xenon arc feeder vessel photocoagulation had chorioretinal (CRN) or choriovitreal (CVN) neovascularization develop. These patients were followed from 2 1/2 to 11 1/2 years with a mean follow-up of 6 years and 8 months. Clinically important late complications of the choroidal neovascularization included vitreous hemorrhage (in three of eight patients with CVN). However, in only two of these three eyes was there any drop in vision related to residual vitreous hemorrhage, and this was limited to loss of only one line of Snellen visual acuity. Therefore, treatment is not usually recommended if CRN or CVN develops after intense photocoagulation. Vitreous fluorophotometry was performed on these patients to examine the breakdown of the blood-retinal barrier. This gave a quantitative measure of fluorescein leakage not obtained with fluorescein angiography. Midvitreous measurements, which are more representative of these peripherally located proliferative lesions than are pre-retinal measurements, suggest that vitreous fluorophotometry may be helpful in differentiating the higher leakage of CVN from the CRN.
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ranking = 1.2
keywords = neovascularization
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4/5. Subretinal neovascularization after focal argon laser for diabetic macular edema.

    The authors reviewed four cases of iatrogenic subretinal neovascularization after focal argon green photocoagulation for clinically significant diabetic macular edema. An inappropriate combination of small spot size with a high-power setting is the common feature in each case of iatrogenic subretinal neovascularization. Close follow-up with fluorescein angiography is used to identify iatrogenic subretinal neovascularization at an early, treatable stage. All four patients responded favorably to laser photocoagulation of the subretinal neovascular membrane.
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ranking = 1.4
keywords = neovascularization
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5/5. Iatrogenic choroidal neovascularization after krypton red laser photocoagulation.

    A major cause for failure of krypton red laser photocoagulation in patients with exudative age-related macular degeneration has been the development of recurrent choroidal neovascularization adjacent to the previously treated areas. After reviewing the possible causes of recurrences, it is apparent that a certain number are iatrogenic, ie, induced by krypton red laser causing disruption and damage to the pigment epithelium-Bruch's membrane-choroidal complex. We describe three separate episodes in two patients of iatrogenic recurrent choroidal neovascularization after krypton red laser photocoagulation.
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ranking = 1.2
keywords = neovascularization
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