Cases reported "Infant, Newborn, Diseases"

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1/8. Early pregnancy loss and neonatal deaths associated with klebsiella pneumonia infection: a mini review of possible occupational health risk.

    Recurrent pregnancy loss is a disease of grave psychological and economic concern. The etiology in the vast majority of the cases is unknown or at best poorly understood. Although klebsiella pneumonia infections have been reported in humans and animals during pregnancy, there is hardly any information to indicate whether or not these infections may be responsible for early pregnancy loss. We present a review of literature and report for the first time in humans, klebsiella pneumonia infection in placenta of a 38-year-old secondary recurrent aborter (parity 2 3).
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keywords = animal
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2/8. Hepatic disease associated with intrauterine parvovirus B19 infection in a newborn premature infant.

    A hydropic premature infant with intrauterine growth retardation died at 4 days of age and was found at necropsy to have advanced liver disease. Clinical and serologic findings in mother and infant were consistent with recent parvovirus B19 infection. parvovirus can cause fetal liver disease in animals, and some instances of congenital hepatic dysfunction in man may be due to intrauterine parvovirus B19 infection.
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keywords = animal
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3/8. Perinatal group B streptococcal infections across intact amniotic membranes.

    We reviewed the perinatal mortality due to group B streptococcal infection over a three-year period at a tertiary center. In 6 of 16 perinatal deaths due to group B streptococcus, representing a range of gestational ages, infection occurred with the membranes intact. A review of reports from the obstetric and pediatric literature revealed that 10-50% of group B streptococcal infections occur in this manner. Several investigators of both animals and humans have demonstrated the pathophysiology of an ascending transamniotic infection. The current series emphasized this mode of infection in group B streptococcal disease.
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keywords = animal
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4/8. Can captopril cause fetal and neonatal renal failure?

    We present a case of neonatal renal failure following a pregnancy complicated by hypertension treated with captopril. Clinical investigations showed structurally normal kidneys, suggesting a renal dysfunction other than that seen with the more common causes of neonatal renal failure. Recent animal and human data would support our hypothesis that transplacental captopril could have produced the clinical picture seen in our patient. Our findings do not unequivocally implicate captopril as the offending agent; however, since captopril is not considered to be teratogenic, a more widespread use may be anticipated in pregnancies complicated by severe hypertension. Surveillance of such pregnancies may yield more information regarding the above association.
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keywords = animal
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5/8. Hazards of calcium gluconate therapy in the newborn infant: intra-arterial injection producing intestinal necrosis in rabbit ileum.

    Five infants received 10% calcium gluconate via umbilical artery catheters, which resulted in intestinal bleeding and lesions of the buttock, anus, groin, and thigh. The effects of intra-arterial calcium gluconate in two animal models were investigated. Injection of calcium into the aorta in the region of the posterior mesenteric artery resulted in immediate hyperperfusion of the descending colon; this may be an early hemodynamic response to injury in the area of colon supplied by this vessel. injections into the arterial arcade of the rabbit ileum resulted in intestinal necrosis and villous atrophy. The use of umbilical artery catheters for administration of calcium gluconate is potentially hazardous.
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keywords = animal
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6/8. Use of whole blood exchange transfusion to supply neutrophils to septic, neutropenic neonates.

    When neutropenia due to exhaustion of the marrow neutrophil reserve, develops in a neonate with bacterial sepsis the likelihood of survival is very small. We report such a case who was treated with a double-volume exchange transfusion using fresh unstored whole blood. We were able to determine a net gain of 5 x 10(8) neutrophils per kg. Then, in neutropenic neonatal animals, neutrophil transfusion by double-volume exchange transfusion with unstored blood was investigated.
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7/8. Accumulation of Tc-99m-sulfur colloid by the lung and kidney following disseminated intravascular coagulation.

    A patient is described who demonstrated accumulation of Tc-99m-sulfur colloid in both the lung and kidney following treatment for disseminated intravascular coagulation. This phenomenon has been demonstrated experimentally in animals following the induction of disseminated intravascular coagulation, but to our knowledge has not been previously described in humans.
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keywords = animal
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8/8. listeriosis.

    Four patients with listeria monocytogenes infection are presented; three of whom had associated lymphoproliferative disorders. Two of the four patients had Listeria meningitis. meningitis is the most common manifestation of listeriosis in humans. Specific diagnosis depends on demonstrating listeria monocytogenes in the cerebral spinal fluid; differentiation from other forms of acute meningitis cannot be made clinically. Although listeriosis is recognized as a major global problem in both human and animal health, the epidemiology of human infection is poorly understood. animals and animal products may serve as reservoirs for human infection. Antibiotic therapy resulted in recovery in three of the patients. The history, epidemiology, laboratory diagnosis, clinical manifestations, and therapy of listeriosis are reviewed.
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keywords = animal
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