21/77. Chorioangioma and its severe infantile sequelae: case report.OBJECTIVE: This case report describes a rare clinical presentation of chorioangioma diagnosed prenatally because of raised-maternal serum (MS) alpha-fetoprotein. methods: A thirty-year-old woman gravida 2, para 1 was referred to the ultrasound unit at 18 weeks of gestation because of abnormal MS triple-test results. This included AFP level of 14.9 MoM; hCG of 3.42 MoM and uE3 of 1.01 MoM. A detailed anomaly scan revealed a singleton fetus with no sonographically detectable malformations and normal amniotic fluid.The placenta was posterior. A well-circumscribed, rounded, predominantly hypoechoic lesion near the chorionic surface measuring 5 x 5 cm and protruding into the amniotic cavity was detected. color Doppler sonogram showed no blood flow within the mass, but clear fetal waveforms in its periphery were demonstrated, and the diagnosis of chorioangioma was made. The pregnancy was followed uneventfully until 35 weeks of gestation when polyhydramnios and severe fetal cardiomegaly developed. Labor was therefore induced. RESULTS: A euploid female, who had multiple diffuse cutaneous and liver angiomatosis was born. She died at the age of one month because of cardiac failure and infection. CONCLUSIONS: The present case alerts to the interrelationship between placental and fetal angiomas. This may lead to severe infantile sequelae because of similar lesions.- - - - - - - - - - ranking = 1keywords = single (Clic here for more details about this article) |
22/77. Neonatal nasal obstruction and a single maxillary central incisor.We present two neonates with nasal obstruction because of anterior choanal stenosis (congenital nasal pyriform aperture stenosis). An associated single maxillary central incisor was also shown on computed tomography imaging in the neonatal period. These midline anomalies are recognized minimal manifestations (microforms) of holoprosencephaly. We describe their neonatal investigation, multidisciplinary management and clinical course.- - - - - - - - - - ranking = 5keywords = single (Clic here for more details about this article) |
23/77. Multiple cerebral aneurysms in a neonate: occlusion and rupture.Aneurysmal subarachnoid hemorrhage in a neonate is exceedingly uncommon. The authors report the case of a neonate with a large anterior communicating artery aneurysm, accessory left middle cerebral artery aneurysm, and left internal carotid artery (ICA) fusiform aneurysm. The neonate suffered from occlusion of the left ICA and aneurysm rupture. The large aneurysm was treated with detachable coils and the patient made a significant recovery. Of the 15 case reports of cerebral aneurysms in neonates that have been published, none has contained a description of multiple aneurysms or a discussion of endovascular treatment.- - - - - - - - - - ranking = 26.804375731253keywords = artery (Clic here for more details about this article) |
24/77. The effect of TNFalpha blockade in complicated, refractory Kawasaki disease.In Kawasaki disease (KD), a systemic vasculitis of childhood, serum levels of proinflammatory cytokines such as tumour necrosis factor alpha (TNFalpha) are elevated during the acute phase of the disease. Although the majority of children recover completely from a single dose of intravenous immunoglobulin (IVIG), the treatment is not always effective. In refractory cases of KD there are no documented treatment guidelines. A future role of biological agents directed against proinflammatory cytokines has recently been suggested by the american heart association (AHA). We describe two infants with severe KD, complicated by coronary as well as extracoronary aneurysms, who responded neither to repeated treatment with IVIG plus aspirin nor to corticosteroids. The children were subsequently treated with infliximab. In both cases, the effect was prompt and long-lasting. Clinical improvement was seen within a few days after the first dose, and regression of the aneurysms occurred within weeks.- - - - - - - - - - ranking = 1keywords = single (Clic here for more details about this article) |
25/77. Neonatal complications at term as related to the degree of umbilical artery acidemia.The degree of umbilical arterial acidemia associated with immediate newborn morbidity has not been determined. Therefore we compared 358 term infants with umbilical artery acidemia (pH less than 7.20) with 358 term, nonacidotic matched control infants, to evaluate immediate neonatal complications in both groups. Nonacidotic was defined as an umbilical artery pH greater than or equal to 7.20. Complications included seizures, persistent hypotonia, and/or signs of end-organ damage such as renal or cardiac dysfunction. None of the 693 newborns with an umbilical artery pH greater than or equal to 7.00 had such complications. Two of 23 infants with an umbilical artery pH less than 7.00 had sequelae related to intrapartum asphyxia. In these two infants the umbilical artery pH was less than 7.00, the 1-minute and 5-minute Apgar scores were less than or equal to 3 and the acidemia was metabolic in nature.- - - - - - - - - - ranking = 105650.87270804keywords = umbilical artery, umbilical, artery (Clic here for more details about this article) |
26/77. Diffuse neonatal hemangiomatosis. A case with heart failure and thrombocytopenia.An examination of the skin in a nine day old infant revealed multiple cherry-red superficial hemangiomas, which progressively increased in size and number. At the age of three weeks these skin lesions involved the scalp, trunk, extremities, palms, soles, and buccal mucous membranes. In addition, similar lesions of the liver and gastrointestinal tract were found. steroids and irradiation were tried with limited success. Finally, hepatic artery ligation was successful in eliminating the heart failure.- - - - - - - - - - ranking = 8.9347919104175keywords = artery (Clic here for more details about this article) |
27/77. Outbreak of meningitis in a newborn intensive care unit caused by a single escherichia coli K1 serotype.Three cases of meningitis that occurred during a nine-day period in a newborn intensive care unit were caused by a single E. coli serotype 07:K1:H-. A single organism outbreak was suspected when the three spinal fluid isolates all possessed the same two unusual bacteriologic and biochemical characteristics: nonmotile and ornithine negative. culture surveillance identified eight infants colonized with the same strain of E. coli; three of these infants are described. Clusters of cases of E. coli meningitis in newborn intensive care units should be evaluated and managed as potential outbreaks.- - - - - - - - - - ranking = 6keywords = single (Clic here for more details about this article) |
28/77. Systemic air embolism in the respiratory distress syndrome of the newborn.Details of 25 cases of neonatal systemic air embolism, including three of our patients, are reviewed. This rare complication of respiratory distress syndrome (RDS) was observed in 21 premature infants and 4 fullterm newborns, of whom 23 required intermittent positive pressure ventilation (IPPV). In 21 of these patients air embolism was preceded by pulmonary interstitial emphysema, pneumomediastinum, pneumothorax and/or pneumopericardium. air embolism occurred between 3 and 288 hours after delivery. The outcome was lethal in 24 cases, only one patient survived. Two main pathogenic mechanisms are discussed; entrance of air from ruptured alveoli into the lung capillaries and introduction of air via catheters in umbilical vessels.- - - - - - - - - - ranking = 1016.2425534989keywords = umbilical (Clic here for more details about this article) |
29/77. Idiopathic infantile arterial calcification in siblings: radiologic diagnosis and successful treatment.Idiopathic infantile arterial calcification is a disorder of unknown etiology manifested by widespread arterial calcification. This usually leads to early death from coronary artery occlusion. In 12 of the 75 cases in the literature, radiographs were taken and it was possible to make the diagnosis in them all. We present two patients, siblings, in whom the diagnosis was established radiologically. The nature of the calcium deposits was studied in one of the infants and proved to be calcium hydroxyapatite. Therapy with diphosphonate was apparently successful in the other child.- - - - - - - - - - ranking = 8.9347919104175keywords = artery (Clic here for more details about this article) |
30/77. Refractory hypoglycemia associated with a malpositioned umbilical artery catheter.An infant with unexplained hypoglycemia who responded poorly to medical management had the tip of his umbilical artery catheter positioned near the major arteries supplying the pancreas. Catheter repositioning resulted in immediate normoglycemia. A "reactive" response to the direct infusion of glucose is postulated on the basis of the clinical response and a decrease in serum insulin/blood glucose ratio.- - - - - - - - - - ranking = 58130.350085856keywords = umbilical artery, umbilical, artery (Clic here for more details about this article) |
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