11/77. The use of recombinant activated factor vii to control bleeding in a preterm infant undergoing exploratory laparotomy.The case of a preterm infant weighing 1120 g who successfully received recombinant activated factor vii (rFVIIa) without complication for control of a life-threatening bleeding event resulting from a ruptured umbilical artery is reported. After performing an exploratory laparotomy at 27 hours of age, hemorrhage from the surgical wound and various sites persisted. By 63 hours of age, the infant had received a total of 192 mL (171 mL/kg) of packed red blood cells, 115 mL (103 mL/kg) of fresh frozen plasma, 8 mL of cryoprecipitate, and 75 mL (67 mL/kg) of platelet concentrate without stabilization. hemorrhage ceased after 2 doses of 40 microg/kg/dose recombinant activated factor vii given at 63 and 70 hours of age, with subsequent stabilization of the hematocrit and without need for additional transfusion therapy.- - - - - - - - - - ranking = 1keywords = umbilical artery, umbilical, artery (Clic here for more details about this article) |
12/77. Umbilical artery catheter use complicated by pseudoaneurysm of the aorta.We report a case of a large aortic mycotic pseudoaneurysm in a premature infant, a rare but serious complication associated with sepsis and umbilical artery catheter (UAC) use. Sonography is an appropriate first-line imaging modality for detection of aortic pseudoaneurysms. Increased awareness of this rare complication may lead to earlier diagnosis in the high-risk premature infant with a history of a UAC and sepsis.- - - - - - - - - - ranking = 1.0071621275895keywords = umbilical artery, umbilical, artery (Clic here for more details about this article) |
13/77. Anomalous origin of left coronary artery from the right pulmonary artery in association with type III aortopulmonary window and interrupted aortic arch.Anomalous origin of the left coronary artery from the pulmonary artery, also known as Garland-Bland-White syndrome, usually occurs as an isolated condition. We report an infant with caudal regression sequence diagnosed with interrupted aortic arch type B and type III aortopulmonary window, who was found to have anomalous origin of the left coronary artery from the right pulmonary artery at surgical repair. Successful repair of the aortopulmonary window and interruption was performed with reimplantation of the left coronary artery into the ascending aorta. This report highlights the importance of closely assessing the coronary ostia in patients undergoing complex aortopulmonary window repair.- - - - - - - - - - ranking = 0.02327691466577keywords = artery (Clic here for more details about this article) |
14/77. Primary cutaneous mucormycosis in infants and neonates: case report and review of the literature.A case of angioinvasive cutaneous mucormycosis in a premature infant, eventually requiring extracorporeal membrane oxygenation therapy, is described. The fungal infection began at the site of a brachial artery catheter that had been covered with an adhesive dressing in the left antecubital fossa. The infection progressed rapidly over a 5-day period, and a left arm amputation was required. Fungal hyphae were present at the margins of resection. The patient eventually had disseminated mucormycosis and died. A second case of cutaneous mucormycosis in another premature infant also is presented. This infant had the infection at an intravenous catheter site. Rapid initiation of surgical debridement of the wound and amphotericin b therapy resulted in patient survival. Eighteen reported cases of cutaneous mucormycosis in neonates were found and are reviewed. Prematurity, low birth weight, broad-spectrum antibiotics, corticosteroid therapy, and local trauma to the skin site were common risk factors. Only 7 of the 18 patients survived. Therapy consisted of local debridement and intravenous amphotericin b. High index of suspicion, early diagnosis, and rapid institution of therapy can improve survival rate. The key to prevention appears to be appropriate skin care.- - - - - - - - - - ranking = 0.0017905318973669keywords = artery (Clic here for more details about this article) |
15/77. Acquired pulmonary vein stenosis as a cause of life-threatening pulmonary hypertension.We report the case of an infant born prematurely at 27 weeks gestational age with life-threatening pulmonary hypertension crisis as a result of left upper pulmonary vein stenosis. Surgical treatment consisted of a lobectomy, which is a safe and effective procedure. Evidence strongly suggests that the venous stenosis may have resulted from hypertonic drugs infused through an umbilical catheter facing the upper left venous-atrial junction.- - - - - - - - - - ranking = 0.10483185006241keywords = umbilical (Clic here for more details about this article) |
16/77. brachial artery pseudoaneurysm in a premature infant.A case of brachial artery pseudoaneurysm in a premature infant is reported. The lesion was surgically resected, and arterial continuity restored by end to end anastomosis. The postoperative period and follow up were uneventful.- - - - - - - - - - ranking = 0.0089526594868345keywords = artery (Clic here for more details about this article) |
17/77. Congenital leukaemia after heavy abuse of permethrin during pregnancy.A single case is described of congenital leukaemia with 11q23/MLL rearrangement in a preterm female newborn. Because of arachnophobia, the mother had heavily abused aerosolised permethrin, a widely used household insecticide. permethrin is considered comparatively safe, but, in view of the mother's history, its potential to induce cleavage of the MLL gene in cell culture was tested. Incubation of the BV173 cell line with 50 micro M permethrin readily induced MLL cleavage.- - - - - - - - - - ranking = 0.00010718580669866keywords = single (Clic here for more details about this article) |
18/77. Mycotic thromboaneurysmal disease of the abdominal aorta in preterm infants: its natural history and its management.Five infants with mycotic complications of umbilical artery catheterization were evaluated with abdominal ultrasound and followed serially to document their natural history. methicillin-resistant staphylococcus aureus was always the infecting organism. There were one female and four male infants and they weighed between 900 and 1,200 g at birth. While two of the catheters were positioned in the abdominal aorta, three were located above the diaphragm. The predominate signs and symptoms included: thrombocytopenia, unexplained anemia, renal failure, hypertension, and embolic phenomena to the toes. Real-time ultrasound always proved sufficient for diagnosis. Serial studies detected the initial aortic thrombosis in three patients and accurately documented its progression to aneurysmal disease over 10 days in one patient and 17 days in another. Three of the infants were diagnosed with aneurysms at their initial examination. Of the five patients, three were treated nonoperatively and died of complications of their aortic disease. One patient was discovered at operation to have necrotic ischemic intestine. Aortic repair was postponed and he died of septic complications. The remaining patient underwent a PTFE interposition graft and survived for 6 months, dying of pulmonary failure with autopsy confirmed graft patency.- - - - - - - - - - ranking = 1keywords = umbilical artery, umbilical, artery (Clic here for more details about this article) |
19/77. Invasive fungal dermatitis in a 770 gram neonate.A 770 g birthweight, 25-weeks gestation infant girl was born from a bigeminal pregnancy. Six days later she developed erythematous "diaper dermatitis" and maceration of the flexural areas. Despite topical antifungal therapy, erythematous plaques appeared 2 days later on the back. Within less than 24 hours, skin erosions with crusting appeared and spread over the whole body. candida albicans was found in cutaneous scales, and blood, umbilical catheter, and cerebrospinal fluid cultures. In spite of intravenous fluconazole therapy, her general condition deteriorated and she died 2 days later. This premature neonate had a typical case of invasive fungal dermatitis, which is characterized by diffuse erosive and crusting cutaneous lesions appearing several days after birth and a high rate of systemic fungal infection (mainly but not exclusively) due to Candida sp. mortality is high and prompt diagnosis and initiation of antifungal therapy appears to be the most important factor for survival.- - - - - - - - - - ranking = 0.10483185006241keywords = umbilical (Clic here for more details about this article) |
20/77. Segmental arterial mediolysis in a preterm.We firstly report on a dystrophic preterm infant with segmental arterial mediolysis (SAM) found in arteries of placental, umbilical and cerebral tissues. These arterial lesions of unknown etiology developing in the elderly are characterized by segmental lysis of the abdominal splanchnic arteries followed by aneurysms and acute bleeding. Typically, the lesions occur in a skip pattern. We could find a small number of SAM in the spleen but much more in placental and umbilical tissues. Rarely, a vascular elastosis and splitting of individual vessels in the spleen and lung could be detected. The histological findings are similar to that of adult patients.- - - - - - - - - - ranking = 0.20966370012482keywords = umbilical (Clic here for more details about this article) |
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