Cases reported "Keloid"

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11/34. Pseudopterygium arising in a patient with multiple keloids.

    We describe an unusual case of mechanical restriction of the globe caused by pseudopterygium formation at the site of a minor ocular injury, which led to a possible link between Ebstein's anomaly and keloids.
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12/34. Case report and summary of literature: giant perineal keloids treated with post-excisional radiotherapy.

    BACKGROUND: Keloids are common benign tumors of the dermis, typically arising after insult to the skin. While typically only impinging on cosmesis, large or recurrent keloids may require therapeutic intervention. While no single standardized treatment course has been established, several series report excellent outcomes for keloids with post-surgery radiation therapy. CASE PRESENTATION: We present a patient with a history of recurrent keloids arising in the absence of an ascribed trauma and a maternal familial history of keloid formation, whose physical examination several large perineal keloids of 6-20 cm in the largest dimension. The patient was treated with surgical extirpation and adjuvant radiation therapy. radiotherapy was delivered to the scar bed to a total dose of 22 Gy over 11 daily fractions. Acute radiotherapy toxicity necessitated a treatment break due to RTOG Grade III acute toxicity (moderate ulceration and skin breakdown) which resolved rapidly during a 3-day treatment break. The patient demonstrated local control and has remained free of local recurrence for more than 2 years. CONCLUSION: radiotherapy for keloids represents a safe and effective option for post-surgical keloid therapy, especially for patients with bulky or recurrent disease.
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13/34. The use of collagen-glycosaminoglycan copolymer (Integra) for the repair of hypertrophic scars and keloids.

    Integra dermal matrix (Integra life Sciences Corp., Plainsboro, NJ) was introduced in 1981, and its use in acute surgical burns is well established. However, Integra also has been found to be useful in the surgical treatment of scars. The Integra neodermis is placed at the time of scar excision and then overgrafted several weeks later with a very thin (6/1000-inch) skin graft. The stabilized matrix appears to resist recurrence better than traditional skin grafts, which have a reported recurrence rate of 59%. Many surgeons have had anecdotal success using Integra for both hypertrophic and keloidal scars. This case series presents several patients who underwent reconstructive surgery with the use of Integra to treat their debilitating scar formation. None of the patients developed significant scar morbidity at the donor site when the skin was harvested for grafting during the second stage of the procedure. All patients had documented success with improved appearance, range of motion, and skin quality.
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14/34. Possible isotretinoin-induced keloids in a patient with Behcet's disease.

    isotretinoin-induced keloid formation has occasionally been reported in patients who have undergone dermabrasion or laser treatment. This report describes a man with Behcet's disease (BD) who was prescribed isotretinoin for nodulocystic acne. After approximately 8 weeks of this treatment, the patient developed extensive keloids. There are no previous reports of possible isotretinoin-induced keloid formation in the setting of BD. This article discusses possible connections between BD, keloid formation and isotretinoin, which may be manifested in this case.
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15/34. keloid formation on palmar surface of hand.

    keloid formation is never seen on the palms of the hands. The occurrence of a large keloid forming after a surgical procedure performed in the palmar surface of the hand of a black female patient is described. This is the first known case report in English literature.
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16/34. Umbilical keloid: an early start.

    A case of umbilical keloid formation following cord separation in an infant is described. Treatment involved excision of the mass and reconstruction of the umbilicus with histological confirmation of the excised lesion. To our knowledge, this is the first report of an umbilical keloid occurring at such an early age.
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17/34. Extensive keloids following hair transplantation.

    hair transplant surgery is a highly successful procedure for improving alopecia. However, this procedure is not without its potential risks and complications. A case of a large keloidal scar following hair transplantation is presented. Those performing hair transplant surgery should be aware of this significant potential complication, especially in Black and Oriental individuals, who are more prone to keloid formation.
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18/34. A keloidal scar of the floor of the mouth and its associations. Case report.

    A case of extensive scarring of the floor of the mouth mucosa is reported. Its unusual position and possible association with keloid formation of the skin is discussed.
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19/34. Functions of polymorphonuclear leukocytes and individuality of Jorge Lobo's disease: absence of the specific leukocyte digestive defect against paracoccidioides brasiliensis.

    Peripheral blood neutrophils (PMNs) from a patient with Jorge Lobo's disease (JLD) digested well phagocytosed paracoccidioides brasiliensis. We found no circulating antibodies against P. brasiliensis in the patient's serum. Such neutrophils showed myeloperoxidase activity and also digested normally phagocytosed candida albicans. We had previously reported the presence of a specific digestive deficiency of PMNs from patients with paracoccidioidomycosis (PARA) vis a vis P. brasiliensis. Current findings provide new information about leukocyte functions in JLD and bolster the view that JLD, PARA and their respective causative microorganisms are distinct.
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20/34. Endodontic therapy averting major surgery and avoiding keloid formation.

    Keloids and mandibular unfavorable fractures are reviewed. A case report of a patient with keloid diathesis, who had a mandibular unfavorable fracture, is presented. A grossly carious, abscessed first molar was in the line of fracture. This tooth was the only erupted tooth present in the proximal fragment. Endodontic therapy and restoration of normal contour enabled the surgeons to treat the fractured mandible by means of simple closed reduction. The endodontic treatment pre-empted a major surgical procedure under general anesthesia and also averted a skin incision which would have subsequently formed a disfiguring keloid.
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