Cases reported "Keratosis"

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1/8. keratoacanthoma developing on a pigmented patch in incontinentia pigmenti.

    Cutaneous manifestations of incontinentia pigmenti (IP) have classically been described as three sequential stages: an initial vesicobullous stage, a verrucous stage and a stage of swirled pigmentation. Verrucous lesions tend to last longer than vesicobullous eruptions, often persisting until 1 year of age. However, adult patients with verrucous lesions are rare. We report a case of keratoacanthoma with marked dyskeratosis on a pigmented patch in a 20-year-old woman. This tumor, like subungual keratotic tumors of IP, might have been developed as one of the late manifestations of the disease.
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ranking = 1
keywords = incontinentia pigmenti, incontinentia, pigmenti
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2/8. incontinentia pigmenti achromians.

    A patient with incontinentia pigmenti archromians, who was born to consanguineous parents, is described. This is the first reported case from iran, to our knowledge. A number of features of this disease belong more properly to classical incontinentia pigmenti.
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ranking = 0.47069666149204
keywords = incontinentia pigmenti, incontinentia, pigmenti
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3/8. incontinentia pigmenti with hyperkeratotic lesions in adulthood and possible squamous cell carcinoma.

    A case of incontinentia pigmenti with extensive and progressive hyperkeratotic lesions at the age of 25 years is reported. The histology showed a keratoacanthoma-like picture and signs compatible with squamous cell carcinoma. To our knowledge this has not been previously reported.
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ranking = 0.27069666149204
keywords = incontinentia pigmenti, incontinentia, pigmenti
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4/8. Hypo- and hyperpigmented areas in incontinentia pigmenti. light and electron microscopic studies.

    incontinentia pigmenti is a rare genodermatosis typically involving three stages: vesiculae, verrucous lesions, and hyperpigmentation. We clinically and pathologically documented a case from shortly after birth until the age of 17 years. Although the first two stages took a regular course, the third stage of the disease was characterized by hypopigmented streaks on the legs in addition to axillary hyperpigmentation. Similar hypopigmented areas were found in the patient's mother. Because pathological investigations of hypopigmented areas have been extremely rare, we performed light and electron microscopic studies and compared these with our findings in hyperpigmented regions. light microscopy showed the hypopigmented streaks with slight epidermal atrophy and a reduced number of melanocytes and skin appendages. However, the main finding was round eosinophilic bodies in the upper dermis. Electron microscopic examination of these bodies demonstrated amorphous material that resembled colloid, suggesting degeneration of basal keratinocytes. Confirming previous reports, in hyperpigmented areas we found a reduction of pigment in those parts of the basal layer overlying melanophages located in the upper dermis.
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ranking = 0.81767416537301
keywords = incontinentia pigmenti, incontinentia, pigmenti
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5/8. Acute skin manifestations of Conradi-Huenermann syndrome in a male adult.

    A man displayed the acute inflammatory cutaneous manifestations and the late "incontinentia pigmenti-like" lesions of Conradi-Huenermann subgroup B of chondrodysplasia punctata. The case appears as unique in the literature in that, to our knowledge, both kinds of skin changes have been described only in newborns or early in infancy.
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ranking = 0.2
keywords = incontinentia pigmenti, incontinentia, pigmenti
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6/8. Painful subungual keratotic tumors in incontinentia pigmenti.

    We report a case of dyskeratotic subungual tumor in a 28-year-old woman. The patient presented achromic lineal lesions, typical of residual incontinentia pigmenti (IP), on her legs. Furthermore, the physical examination showed anodontia of the right incisor tooth. The familial background demonstrated miscarriages of male fetuses and characteristic dental abnormalities of IP in female siblings. The patient's daughter presented a typical background of IP and dyschromic splashed lesions. light and electron microscopic studies of the subungual tumors were made. The analogy between subungual tumors of IP and keratoacanthoma is emphasized.
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ranking = 1
keywords = incontinentia pigmenti, incontinentia, pigmenti
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7/8. Histologic changes resembling the verrucous phase of incontinentia pigmenti within epidermal nevi: report of two cases.

    A wide spectrum of histopathologic changes has been reported to occur within epidermal nevi. We saw two patients with warty nevoid lesions in which histopathologic features of incontinentia pigmenti, verrucous phase, were present. The diagnosis of incontinentia pigmenti was excluded because both patients were male, lacked a preceding vesicular stage, and did not demonstrate other features of the disorder.
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ranking = 1.2
keywords = incontinentia pigmenti, incontinentia, pigmenti
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8/8. Late, painful, subungual hyperkeratosis in incontinentia pigmenti.

    The postpubertal appearance of subungual, painful keratotic tumors is a rare feature of incontinentia pigmenti. A patient affected by incontinentia pigmenti developed subungual, painful, nontumoral, hyperkeratotic lesions of the hands at 10 years of age. The mildness of the subungual lesions may be explained by the early stage of the disorder, but it is difficult to correlate the severity of the fingertip pain with the absence of true tumoral swelling. To our knowledge this is the youngest patient reported so far and the only one with a prepubertal expression of this puzzling disorder.
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ranking = 1.2
keywords = incontinentia pigmenti, incontinentia, pigmenti
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