Cases reported "Language Disorders"

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1/3. A case of pure word deafness associated with landau-kleffner syndrome: a long-term study of auditory disturbance.

    A long-term study of auditory disturbance of a female case who had suffered from pure word deafness associated with landau-kleffner syndrome was reported. The patient developed this syndrome at age 4, and we continued the follow-up until she reached 20. The following became clear after the investigation: (1) even by the age of 20 her auditory defect had not improved significantly; (2) from an early stage she could not identify either vowels or consonant-vowel syllables; (3) later she had no difficulty identifying vowels, but her consonant-discrimination score hardly improved; and (4) her problem in consonant identification was unique in that she could discriminate between the voiced and voiceless group but had great difficulty identifying the consonants within each group. These findings led to the conclusion that the patient is unable to recognize short time duration consonants due to an insensibility to loudness and a defect in temporal resolution.
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ranking = 1
keywords = voice
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2/3. Phonagnosia: a dissociation between familiar and unfamiliar voices.

    A dissociation between facial recognition and facial discrimination is well known, but investigations of "phonagnosia" (impairment of voice recognition and discrimination) have not been pursued. Using familiar and unfamiliar voices as stimuli, a marked difference between the ability to recognize familiar voice and the ability to discriminate between unfamiliar voices was identified in five patients, and a sixth showed a severe impairment in both tasks. Clinical and radiologic findings in these cases suggest that recognition of familiar voices is impaired by damage to inferior and lateral parietal regions of the right hemisphere, whereas impairment of voice discrimination abilities is associated with temporal lobe damage of either hemisphere. This dissociation of recognition and discrimination of the human voice suggests that these two functions are mediated by different brain structures and may contribute differentially clinical syndromes.
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ranking = 5.5
keywords = voice
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3/3. Left tuberothalamic artery territory infarction: neuropsychological and MRI features.

    We examined a 29-year-old woman who had language disturbances and memory impairment after a left thalamic infarction. MRI showed injury that was limited to the tuberothalamic artery territory. Beside reduced voice volume and verbal memory trouble, she presented with aspontaneity, loss of psychic self-activation and affective drive. Considering thalamic lesions, this loss of psychic self-activation or 'athymhormie' was found in a left thalamic infarct and could not be considered as an exclusive characteristic of bithalamic infarctions. The disappearance of the neurobehavioral disturbances within 15 days after the onset of the troubles was associated with the decreasing of the mass lesion found by MRI.
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ranking = 0.5
keywords = voice
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