Cases reported "Laryngeal Diseases"

Filter by keywords:



Filtering documents. Please wait...

1/4. Laryngeal involvement in systemic lupus erythematosus.

    Laryngeal involvement in systemic lupus erythematosus (SLE) can range from mild ulcerations, vocal cord paralysis, and edema to necrotizing vasculitis with airway obstruction. In this report, four cases showing the range of severity of this disease manifestation are presented, accompanied by a comprehensive review of the literature. The clinical course of 97 patients with laryngeal involvement with SLE are reviewed, of whom 28% had laryngeal edema and 11% had vocal cord paralysis. In the majority of cases, symptoms such as hoarseness, dyspnea, and vocal cord paralysis resolved with corticosteroid therapy. Other, less common causes of this entity included subglottic stenosis, rheumatoid nodules, inflammatory mass lesions, necrotizing vasculitis, and epiglottitis. The clinical presentation of laryngeal involvement in patients with SLE follows a highly variable course, ranging from an asymptomatic state to severe, life-threatening upper airway compromise. With its unpredictable course and multiple causations, this complication remains a diagnostic and therapeutic challenge to physicians involved in the care of patients with SLE.
- - - - - - - - - -
ranking = 1
keywords = necrotizing
(Clic here for more details about this article)

2/4. hydralazine hoarseness. A new appearance of drug-induced systemic lupus erythematosus.

    Otolaryngologic involvement is rarely a manifestation of drug-induced systemic lupus erythematosus (SLE). hoarseness developed in a 60-year-old man that was secondary to ulcerated lesions, which involved the epiglottis and aryteno-epiglottic folds, with serologic evidence of SLE after he had been treated with hydralazine for six months. Histopathologic study of an epiglottic "pseudotumor" disclosed necrotizing vasculitis. To our knowledge, this is the first reported case of laryngeal involvement as a complication of hydralazine-induced SLE.
- - - - - - - - - -
ranking = 0.5
keywords = necrotizing
(Clic here for more details about this article)

3/4. Necrotizing sialometaplasia of the larynx. A report of two cases and a review of the literature.

    Two cases of necrotizing sialometaplasia of the larynx are reported. One of the cases occurred in the subglottic larynx of a 37-year-old woman and the other occurred in the right false vocal cord of a 59-year-old man. In both of the cases, the sialometaplasia was identified in association with another pathologic process. The female patient presented with dysphagia. Excisional biopsy was performed twice in the span of an 8-day period. Both biopsy specimens showed fibrosis. The subglottic stenosis was felt to be of undetermined origin. There was evidence of necrotizing sialometaplasia in only the second biopsy material. Subsequently, the patient was diagnosed as having relapsing polychondritis, the probable cause of the subglottic stenosis. The male patient presented with increasing hoarseness and was found to have a mass of the right false vocal cord. biopsy of the mass was diagnostic for a poorly differentiated squamous cell carcinoma with separate foci of necrotizing sialometaplasia. In both cases, it appears that the sialometaplasia occurred secondary to the other pathologic processes with the likely pathogenesis the result of vascular compromise to the affected area.
- - - - - - - - - -
ranking = 4813.5893231736
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
(Clic here for more details about this article)

4/4. Neuro-laryngeal involvement in churg-strauss syndrome.

    We report our clinical experience in managing a 59-year-old Italian male with churg-strauss syndrome (CSS) whose first clinical manifestation was a persistent dysphonia; the patient worked as a mechanic. Video-laryngostroboscopic examination revealed paresis of the right vocal fold with a reduction in adduction together with incomplete glottal closure. Spectrographic and spirometric tests both showed abnormal changes. Laryngeal electromyography revealed neurogenic damage of the right thyroarytenoid and crycoarytenoid muscles. Due to the appearance of typical signs of systemic involvement of CSS as a necrotizing vasculitis, the patient was admitted to the rheumatology Unit of the University of Pisa. Histologic analysis of a skin lesion on the patient's foot confirmed the diagnosis. Treatment with 6-methylprednisolone quickly brought remission from systemic and laryngeal symptoms, as well as improvement in the results of video-laryngostroboscopic, spectrographic and laryngeal myographic tests.
- - - - - - - - - -
ranking = 0.5
keywords = necrotizing
(Clic here for more details about this article)


Leave a message about 'Laryngeal Diseases'


We do not evaluate or guarantee the accuracy of any content in this site. Click here for the full disclaimer.