Cases reported "Leiomyoma"

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11/57. Preoperational diagnosis of a uterine lipoleiomyoma using ultrasound and computed tomography images: a case report.

    A uterine lipoleiomyoma is a variant of uterine myomas, however, it is rarely found in patients and the diagnosis of uterine lipoleiomyoma has always been in retrospect. Uterine lipoleiomyomas are often diagnosed preoperatively as uterine myomas or ovarian mature teratomas. The key to distinguishing the tumors from lipoleiomyomas is to ascertain the primary site of development--uterus or adnexa. When a large uterine tumor is found in a postmenopausal woman, the possibility of malignancy should be considered. Now, however, advanced modern imaging systems can provide more precise diagnoses than before. The following case illustrates how a uterine lipoleiomyoma was highly suggestive preoperatively based on typical characteristics on ultrasound and computed tomography (CT). A homogeneous hyper-echoic mass confined to the uterus on ultrasound initiated the suspiction of the tumor. In addition, the uterine mass showed lower density than water on CT which further established the possibility of a fatty tumor of the uterus. The final pathological examination results confirmed the diagnosis of lipoleiomyoma.
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keywords = fat
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12/57. Two fatal complications after parallel tracheal-esophageal stenting.

    Two patients with malignant obstructions of both the trachea and esophagus underwent parallel stent placement with Gianturco-Rosch Z (GRZ) stents for palliation of symptoms. Fatal hemorrhage occurred in both patients 2 and 3 weeks after stent placement respectively. An autopsy performed on one of these patients demonstrated esophageal tissue necrosis and erosion with perforation of both the tracheal and esophageal walls at sites where the stent struts were in direct opposition, leading to bleeding from the esophageal venous plexus. GRZ stents have been successful in the treatment of both solitary tracheal and esophageal stenoses. However, parallel tracheal-esophageal stenting with GRZ stents places patients at high risk for complications due to the high radial force exerted by this particular stent and the minimal amount of intervening tissue between the two structures.
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keywords = fat
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13/57. Malignant mesenchymoma of the uterus, arising in a leiomyoma.

    AIMS: To document and find evidence for the rare occurrence of malignant progression of a benign uterine leiomyoma with divergent mesenchymal differentiation. In a 54-year-old female a large pedunculated tumour was encountered which had suddenly increased in size and had apparently arisen at the site of a subserosal uterine leiomyoma first described 19 years earlier. The tumour seemed histologically diverse in its composition. The possibility of malignant progression of the benign leiomyoma with divergent mesenchymal differentiation was entertained. methods AND RESULTS: In the resected tumour, smooth muscle, osseous and adipose components were identified and these were assessed using recognized histological criteria of malignancy. In addition to a benign smooth muscle component, malignant leiomyosarcomatous tissue was seen in addition to a malignant osseous component and a malignant adipose component. The tumour thus met the criteria of a malignant mesenchymoma. The relationship of the different components of the tumour was analysed by immunohistochemistry and with molecular loss of heterozygosity (LOH) analysis. In the osseous and leiomyosarcomatous components a similar LOH pattern was observed. The adipose component showed a distinct LOH pattern. Retention of smooth muscle differentiation in the osseous component was demonstrated by desmin immunostaining. CONCLUSION: Malignant transformation of benign uterine leiomyoma may rarely occur. Mesenchymal stem cells underlying these tumours may show divergent mesenchymal differentiation.
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ranking = 489.44242571333
keywords = adipose
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14/57. Myolysis of the erector spinae muscles as the cause of scoliosis in osteoid osteoma of the spine.

    STUDY DESIGN: A case of an osteoid osteoma at the lower thoracic spine with scoliosis is reported. OBJECTIVES: To suggest that myolysis of the erector spinae muscles reflected by signal abnormalities on magnetic resonance images causes back pain, protective muscle contraction, and scoliosis. SUMMARY OF BACKGROUND DATA: Osteoid osteomas of the spine are frequently accompanied by scoliosis. The proposed mechanism of the scoliosis has been explained as a postural adaptation of the spine through predominant muscle spasm on the concave side. methods: The history of the patient and radiologic, magnetic resonance imaging, and histologic findings of the peritumoral area were reviewed. RESULTS: Magnetic resonance images showed signal abnormalities on muscles surrounding the tumor, and use of gadopentetate dimeglumine resulted in an enhancement. The microscopic examination of the erector spinae muscles that demonstrated high intensities on T2-weighted images showed derangement or destruction of the muscle fibers and replacement of the muscle fibers with fat tissue and infiltrating inflammatory cells. CONCLUSION: These findings were interpreted as those of myolysis. The suggested mechanism of the induction of scoliosis by the present osteoid osteoma is that the unaffected iliocostalis and quadratus lumborum muscles on the tumor side predominantly contracted over those on the opposite side to decrease the tension of the erector spinae muscles involved in myolysis, thereby producing a functional scoliosis.
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15/57. Fatal sepsis after uterine artery embolization with microspheres.

    A case report of fatal sepsis after uterine artery embolization (UAE) with microspheres is presented. At autopsy, microspheres were found not only in arteries in the leiomyomata and myometrium but also in the parametria and the vagina, leading to a necrotic vaginal wall and uterine cervix. At present, polyvinyl alcohol particles are usually used in UAE. Recently, study results of the use of microspheres in embolization procedures have become available. The rationale for the choice of a specific embolization particle and the clinical implications of possible sepsis after UAE are discussed.
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16/57. Giant peritoneal loose body in the pelvic cavity: report of a case.

    This report describes a giant peritoneal loose body in the pelvic cavity. A 63-year-old man who was asymptomatic underwent a routine medical examination, which revealed a tumor in the pelvic space. Computed tomography and magnetic resonance imaging showed a smooth-surfaced mass with two marked calcifications in the central position. Preoperatively, we suspected a calcified leiomyoma originating from the wall of the sigmoid colon; however, at laparoscopic surgery we extracted a hard, egg-shaped mass 5 cm in diameter, with detached appendices epiploicae. Histological examination revealed that this peritoneal loose body was made up of thick layers of fibrous tissue with a few cellular components, and necrotic fat tissue in the central position. Small peritoneal loose bodies are occasionally found during laparotomy or autopsy, but such a large one is very unusual.
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17/57. The coincidence of pure lipoma, leiomyoma, and endometrial cancer. A case report of the uterine tumor triplicity.

    A different tumor concurrence of the uterine body is usually encountered as a coincidence of leiomyoma and endometrial cancer. Pure lipomatous tumors or fatty change in the leiomyoma or endometrium are rare affections with some diagnostic peculiarities. We present a case of association of the pure uterine lipoma, leiomyoma, and endometrial cancer as a tumor triplicity, which may contribute, to the pathogenesis of mesenchymal tumors in this location.
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keywords = fat
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18/57. Lipomatous lesions of the uterus.

    Four lipomatous lesions of the uterus are reported and the available literature from 1965 to 1976 is reviewed. It is suggested that these lesions result from metamorphosis of uterine smooth muscle which can proceed to form localised or diffuse mature adipose tissue in a leiomyoma or in the myometrium. Three terms are suggested for the nomenclature of the various morphological types of lipomatous lesions of the uterus: diffuse lipomatosis in a leiomyoma, circumscribed lipomatosis in a leiomyoma and uterine lipoma.
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ranking = 163.14747523778
keywords = adipose
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19/57. Myolipoma of the retroperitoneum.

    A case of retroperitoneal myolipoma is reported. A 55-year-old woman with the main complaint of an abdominal mass was admitted to Teikyo University Hospital, tokyo, japan. Retroperitoneal liposarcoma was suspected based on magnetic resonance imaging, and the tumor was resected. The resected tumor was well encapsulated and 30 x 15 x 8 cm in size. Histologically, it consisted of mature adipose cells and smooth muscle cells. Neither nuclear atypia nor mitosis was observed in either component. The tumor was pathologically diagnosed as myolipoma of the retroperitoneum. Retroperitoneal myolipoma is often misdiagnosed radiologically as liposarcoma because the overwhelming majority of large retroperitoneal tumor containing fat is liposarcoma, however, the clinical course of myolipoma is quite different from that of liposarcoma. Although myolipoma is very rare, pathologists should consider it in the differential diagnosis of fat-containing retroperitoneal masses.
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ranking = 165.14747523778
keywords = adipose, fat
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20/57. Uterine lipoleiomyoma: a histopathological review of 17 cases.

    Lipoleiomyoma is a rare uterine tumor. The exact frequency and proliferation activity are not yet known. This study aims to know the frequency and evaluate the relation with renal angiomyolipoma. Lipoleiomyoma cases were immunohistochemically stained by antibodies for Ki-67, melanoma specific antigen HMB45, S-100 protein, and alpha smooth muscle actin (alpha-SMA). Frequency of uterine lipoleiomyoma among uterine myomatous tumor was 17/4904 (0.35%) in the Department of Human pathology, Field of Oncology, Kagoshima University Graduate School database (1983-2003). patients ranged from 45 to 74 years of age, and 10 cases were associated with leiomyoma. Six of 17 (35%) cases showed areas with renal angiomyolipoma-like vessels and atypical cellular features. Immunostaining was available in 12 cases. By Ki-67 labeling index, both muscle (average 1.38%) and fat (average 1.17%) portions of the tumor had greater proliferation than normal myometrium (average 0.76%), which suggests that fat portions of the tumor are proliferating adipose tissue rather than fatty degeneration of muscular counterpart. HMB45 antigen, which is positive in renal angiomyolipoma, was negative in three uterine cases having angiomyolipoma-like vessels (3/12). However, HMB45 antigen was positive in spindle-shaped tumor cells of three cases (3/12) which lacked angiomyolipoma-like vessels. Presence of angiomyolipoma-like blood vessels in these tumors is not an uncommon feature. However, the diagnosis of uterine angiomyolipoma should not be based on the result of HMB45 antigen immunoreactivity alone.
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ranking = 166.14747523778
keywords = adipose, fat
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