Cases reported "Lung Diseases, Fungal"

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11/35. Treatment of cavitary pulmonary zygomycosis with surgical resection and posaconazole.

    We describe a 57-year-old woman with acute lymphoblastic leukemia who had a cavitary lesion develop in the right upper lobe caused by cunninghamella bertholletiae, a zygomycete. The infection was resistant to both high-dose liposomal amphotericin b and voriconazole. The current report demonstrates successful treatment, even in the setting of subsequent bone marrow transplantation and immunosuppression, using a combination of surgical resection and posaconazole therapy.
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ranking = 1
keywords = zygomycosis
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12/35. Pulmonary zygomycosis in a diabetic patient.

    We report a case of pulmonary zygomycosis in an adult male diabetic patient who presented with fever and altered sensorium initially and later developed streaky haemoptysis. bronchoscopy showed picture of necrotizing pneumonia. sputum was negative for fungal elements on admission but later bronchial wash and repeat sputum samples were positive by microscopy and culture showed growth of rhizopus species. Immediately the patient was put on amphotericin b but had a bout of massive haemoptysis and succumbed. A high index of suspicion is needed for an early diagnosis and aggressive treatment of this infection in view of the high mortality rate.
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ranking = 1.25
keywords = zygomycosis
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13/35. multiple pulmonary nodules caused by zygomycosis in a patient without predisposing factors.

    We report a case of a 61-year-old male without any predisposing factors. His x-ray film showed multiple nodular lesions in bilateral lung fields. Open lung biopsy revealed Zygomycetes in the granuloma. The patient was treated with amphotericin b and miconazole, and remains alive more than 32 months later.
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ranking = 1
keywords = zygomycosis
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14/35. Granulomatous pulmonary zygomycosis in a patient without underlying illness. Computed tomographic appearances and treatment by pneumonectomy.

    Pulmonary zygomycosis rarely occurs in the absence of underlying disease. We report a patient with granulomatous pulmonary zygomycosis without underlying disease who presented with a pulmonary mass. We present the computed tomographic findings that we believe have not been described previously. We also report the successful treatment by pneumonectomy.
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ranking = 1.5
keywords = zygomycosis
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15/35. Endobronchial zygomycosis.

    Pulmonary zygomycosis is an uncommon opportunistic fungal infection. Diabetics have a tendency to develop major airway lesions. This can lead to invasion of the airway wall and hilar vessels with infarction and severe haemoptysis. Aggressive early surgery appears to offer the best chance of recovery.
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ranking = 1.25
keywords = zygomycosis
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16/35. zygomycosis. Report of four cases with formation of chlamydoconidia in tissue.

    The authors describe spheric to ovoid chlamydoconidia and mucoraceous hyphae in tissues from four patients, two with cutaneous and two with pulmonary zygomycosis. The diagnosis in each case was confirmed by immunofluorescence staining and the presence of characteristic hyphae in tissue. It is important that these conidia be recognized, because they can easily be mistaken for other fungi, nematode ova, or other microorganisms in tissue sections, thereby resulting in the potential for misdiagnosis.
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ranking = 0.25
keywords = zygomycosis
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17/35. Pulmonary complications in diabetes mellitus.

    diabetes mellitus produces serious complications in several major organ systems. The pulmonary complications, although uncommon and not well recognized, may be life-threatening. We describe a 20-year-old patient with diabetic ketoacidosis in whom pulmonary zygomycosis developed. This condition was complicated by stenosis of the left upper lobe bronchus despite successful treatment of the zygomycosis. Bronchial obstruction has become a well-recognized complication of pulmonary zygomycosis. In addition to infections caused by Zygomycetes, mycobacteria, viruses, and bacteria, the pulmonary complications described in patients with diabetes include pulmonary edema, disordered breathing during sleep, and reductions in elastic recoil of the lungs, diffusing capacity of the lungs for carbon monoxide, and bronchomotor tone. Other reported complications are respiratory alkalosis, cardiorespiratory arrest, pneumothorax, pneumomediastinum, plugging of the airways with mucus, and aspiration pneumonia attributable to diabetic gastroparesis.
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ranking = 0.75
keywords = zygomycosis
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18/35. survival of a recipient of renal transplantation after pulmonary phycomycosis.

    A 48-year-old nondiabetic man maintained on prednisone, azathioprine, and cyclosporine after cadaveric renal transplantation developed multiple unilateral phycomycotic pulmonary abscesses. Despite treatment with amphotericin b the patient remained febrile. Surgical resection of these pulmonary abscesses was performed and the patient remains free of disease 1 year after operation. To our knowledge, this patient represents the first reported case of pulmonary phycomycosis in a recipient of renal transplantation without diabetes mellitus.
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ranking = 2.9663183779059
keywords = phycomycosis
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19/35. Simultaneous disseminated aspergillosis and zygomycosis in a leukemic patient.

    Although the incidence of fungal infections is increasing, infections caused by more than one fungus are rare. We have described the clinical, pathologic, and mycologic findings in a leukemic patient with simultaneous pulmonary infection and systemic dissemination caused by aspergillus fumigatus and rhizopus sp.
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ranking = 1
keywords = zygomycosis
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20/35. Pulmonary zygomycosis. A cause of positive lung scan diagnosed by bronchoalveolar lavage.

    The diagnosis of pulmonary zygomycosis usually depends on the detection of fungal hyphae in biopsied tissue specimens. We describe a patient with a high-probability lung scan and diffuse pulmonary infiltrates due to Zygomycetes diagnosed by the demonstration of nonseptate hyphae in bronchoalveolar lavage fluid.
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ranking = 1.25
keywords = zygomycosis
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