Cases reported "Lung Diseases, Parasitic"

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1/29. Pulmonary presentation of dirofilaria immitis (canine heartworm) in man.

    Canine heartworm or dirofilaria immitis can occasionally infect man. We present the case of a 36-year-old Balkan woman referred to us for a thoracoscopic biopsy of a well defined pulmonary mass. The latter was thoracoscopically resected and proved to be due to dirofilaria immitis on histopathological examination. To our knowledge this is the second reported case in western australia, the first being that reported by Brine et al. The prevalence of the disease in Australia was recognized in 1969 in one study in the state of queensland, where 12% of 761 dogs at one veterinary clinic and 20% of 296 dogs at another were shown to be infected. dirofilaria immitis resides in the right ventricle and pulmonary arteries of dogs. The microfilariae are released into the blood stream and are transmitted to secondary hosts by mosquitoes.
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2/29. The first Korean case of human pulmonary dirofilariasis.

    Human pulmonary dirofilariasis has been documented from many parts of the world, but not in korea so far. We experienced a patient of pulmonary dirofilariasis who had visited a local clinic because of chest pain for 1 month. On chest radiograph, a coin lesion of 2 cm diameter and enlargement of the mediastinal lymph node were shown. An exploratory lung resection was done. Pathologically the lesion was a pulmonary dirofilariasis complicated with necrotic pneumonia, fibrosis, and infarction. At the center of the lesion, degenerated nematode sections with multilayered cuticle, thick musculature, and bilateral internal ridges on each side were found, which was identified to be dirofilaria immitis. This is the first report of human pulmonary dirofilariasis in korea.
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keywords = immitis
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3/29. Human pulmonary dirofilariasis presenting as a small nodule with a cavity.

    A 73-year-old woman had a 4-year history of lung fibrosis from collagen vascular disease. She presented with a complaint of dry cough. A chest radiograph showed a 2-cm solitary pulmonary nodule with a small cavity in the right lower lobe. Preoperatively, we performed computed tomography of the chest and measured tumor markers. Video-assisted thoracotomy was performed because we could not rule out lung cancer. Pathologic analysis confirmed the presence of a granuloma with dirofilaria immitis. In japan, the incidence of human dirofilariasis has steadily increased and must be considered in the workup of cavitary pulmonary nodules.
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keywords = immitis
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4/29. Human pulmonary dirofilariasis. A case report and review of the literature.

    A case of pulmonary dirofilariasis in a 48-year-old woman is presented. This rare pulmonary disorder is caused by dirofilaria immitis, the canine heartworm. A review of the literature revealed 40 documented cases, most of which have occurred in the united states within the past 10 years. The incidence of pulmonary dirofilariasis appears to be increasing; thus, this entity represents an important zoonosis and indicates a need for familiarity with the pathologic features of the lesions and the morphologic characteristics of the worm.
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keywords = immitis
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5/29. Pulmonary dirofilariasis--clinicopathological study.

    Pulmonary dirofilariasis (PD), caused by dirofilaria immitis (D. immitis), the dog heartworm, is not common in humans, though we recently encountered 4 cases. Chest X-ray images from annual health examinations showed a single spherical nodule in the inferior or middle portion of the right lung in each patient. None of the patients showed any clinical symptoms and had no contact with dogs. Hematological results in 3 of the cases were within normal limits, while mild eosinophilia was found in one. Serological tests for the Anti-Dirofilaria antibodies were not performed. There were no characteristic clinical manifestation of PD in any of the patients, however, we consider it important to keep a diagnosis of PD in mind, when we experienced these cases, they present no characteristic clinical manifestations. Pathologically, macroscopic findings showed well-circumscribed nodules that were round peripheral lesions in lungs. Histological results revealed coagulation necrosis with fibrosis and granulation in the nodule edge, which contained inflammatory cells. By means of silver staining, the worm structures in the nodules could be identified well, and the quadrant cells in the sections were numbered about 30. Immunohistochemically, the somatic muscle tissues were stained with anti-Dirofilaria antibody. These findings indicated that the pulmonary lesions in all 4 cases were due to D. immitis.
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ranking = 0.42857142857143
keywords = immitis
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6/29. Human pulmonary dirofilariasis in taiwan.

    Pulmonary dirofilariasis is a rare zoonotic disease in the united states. Most reported cases were from the southeastern or Gulf states. The disease is caused by dirofilaria immitis (dog heartworm), a filarial nematode, and is transmitted to humans by mosquitoes. A 69-year-old asymptomatic man was found to have a pulmonary nodular lesion on chest x-ray during routine health examination. The lesion was resected, and pulmonary dirofilariasis was diagnosed based on histological findings. Postoperatively, recovery was uneventful. This is the second reported case of human pulmonary dirofilariasis in taiwan. awareness of this entity is important, since the clinicoradiographic presentation of human pulmonary dirofilariasis may mimic lung neoplasia. This case may help alert clinicians, radiologists, or pathologists that pulmonary dirofilariasis should be included in the differential diagnosis when a subpleural 'coin-like' lesion is observed on chest x-ray.
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keywords = immitis
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7/29. Human pulmonary dirofilariasis in a patient whose clinical condition altered during follow-up.

    Pulmonary dirofilariasis is a rare disease. We have experienced a case which developed pleural effusion while being followed, rendering it difficult to establish the diagnosis. The patient, a 53-year-old woman, had previously undergone two operations; one for uterine cancer and another for breast cancer. She developed a cough in February 2002, and chest computed tomography (CT) scans disclosed a nodular mass in the right lung. A biopsy revealed a fibrous nodule with macrophage aggregation. pleural effusion was demonstrated on chest CT scans performed in May. As the possibility of malignant tumor could not be ruled out, an operation was undertaken. The nodular lesion showed marked coagulation necrosis, and dead parasites were noted in the vascular lumen. The parasites had the characteristic morphological features of dirofilaria immitis. Immunological studies produced a positive test result for the anti-dirofilaria immitis antibody; hence a diagnosis of pulmonary dirofilariasis was made.
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ranking = 0.28571428571429
keywords = immitis
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8/29. dirofilaria immitis: a rare, increasing cause of pulmonary nodules.

    dirofilariasis is an unusual but increasing cause of solitary pulmonary nodules. In this study, we reviewed the entire experience with dirofilariasis at our institution. Five such patients were identified. In all patients, the dirofilaria immitis infection manifested as a solitary pulmonary nodule, and all patients underwent thoracotomy for diagnosis. None required systemic treatment. D. immitis is found in dog, cat, wolf, coyote, and fox populations throughout the united states, but the highest concentrations have been noted in the eastern, southeastern, and southern coastal states. The distribution of human cases of D. immitis infection has a similar pattern. Pulmonary dirofilariasis should be included in the differential diagnosis of peripheral noncalcified pulmonary nodules, especially in endemic areas.
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9/29. Case of the month. A case report of human pulmonary dirofilariasis in arkansas.

    Our patient, a resident of arkansas, presented with a solitary pulmonary nodule for lung resection to rule out primary lung cancer. However, pathologic examination showed the lung nodule to be a granuloma secondary to dirofilariasis. Human pulmonary dirofilariasis is a rare zoonotic disease caused by dirofilariasis immitis (dog heartworm) that is usually transmitted from dogs to human by mosquito bite. To our knowledge, human pulmonary dirofilariasis has previously not been reported in arkansas. In addition, awareness of this entity in the appropriate clinical and epidemiologic setting is important in the differential diagnosis of solitary pulmonary nodules.
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ranking = 0.14285714285714
keywords = immitis
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10/29. Pulmonary dirofilariasis with serologic study on familial infection with dirofilaria immitis.

    An asymptomatic patient with a pulmonary coin lesion surgically diagnosed with pulmonary dirofilariasis caused by infection with dirofilaria immitis (D. immitis) is presented. The preoperative stored serum of the patient was positive for D. immitis by enzyme-linked immunosorbent assay (ELISA). A family study showed that three of five family members were seropositive for D. immitis. These results suggest that family members of a patient with pulmonary dirofilariasis were frequently exposed to D. immitis and serodiagnostic methods are useful for detecting subclinical infection of D. immitis.
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ranking = 1.4285714285714
keywords = immitis
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