Cases reported "Malaria"

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1/289. guillain-barre syndrome following malaria.

    Two adult males were admitted with acute are flexic quadriplegia and bifacial and bulbar weakness 2 weeks after an acute episode of malaria, one due to Plasmodium falciparum infection (patient 1) and the other due to plasmodium vivax (patient 2). cerebrospinal fluid analysis and nerve conduction studies confirmed the diagnosis of guillain-barre syndrome (GBS). Patient 1 progressed to develop respiratory paralysis and required mechanical ventilation. He received intravenous immunoglobulins for the GBS and made a complete recovery in 6 weeks. A review of 11 cases of GBS (nine previously reported and the present two) revealed that eight patients had preceding falciparum malaria and three had vivax infection. All but two patients had distal symmetric sensory deficits. Paralysis was mild in seven cases (three due to P. vivax and four due to P. falciparum) and recovered completely in 2-6 weeks without any specific treatment. Four patients with falciparum malaria developed severe paralysis with respiratory failure, and three patients died. One patient who received intravenous immunoglobulins recovered completely (patient 1 in this report).
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2/289. Transfusion-transmitted malaria--missouri and pennsylvania, 1996-1998.

    Malaria is a rare but potentially serious complication of blood transfusion. During 1958-1998, 103 cases of transfusion-transmitted malaria in the united states were reported to CDC. This report summarizes the investigation of three cases that occurred during 1996-1998 in missouri and pennsylvania and illustrates the key features of transfusion-transmitted malaria and the importance of donor screening.
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3/289. Gangrenous stomatitis (cancrum oris): clinical features, etiologic factors, and complications.

    Gangrenous stomatitis (cancrum oris) is a lesion involving the orofacial structures that is primarily seen in areas where the socioeconomic standards are low and there is poor hygiene. The general clinical features, associated etiologic factors, and ensuing complications in eight consecutive cases diagnosed between 1991 and 1995 are presented and discussed.
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4/289. Rare quadruple malaria infection in Irian Jaya indonesia.

    We report an exceptional finding from a blood slide collected in a remote area in the western half of new guinea Island (Irian Jaya Province, indonesia). One adolescent patient was found patently coinfected with all 4 known human malaria species, plasmodium falciparum, plasmodium vivax, plasmodium malariae, and plasmodium ovale. Diagnostic erythrocytic stages of all 4 species were clearly seen in the peripheral blood. A nested polymerase chain reaction, using species-specific primer pairs to detect dna, helped substantiate this finding. Previous reports from africa, thailand, and new guinea have detected all 4 species in a population but not simultaneously in an individual with a patent, microscopically detectable infection. We believe this quadruple infection represents the first reported natural case of all 4 human malaria parasites observed concurrently in the peripheral blood from a single Giemsa-stained slide.
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5/289. Medical treatment of the adolescent drug abuser. An opportunity for rehabilitative intervention.

    Illnesses related to both the pharmacologic properties of abused substances and their methods of administration often bring the teenager to medical attention and may provide sufficient motivation for the adolescent to seek help beyond the acute problem. Successful treatment of an overdose reaction, an abstinence syndrome, or any other medical complication of drug abuse may give the physician a unique opportunity to begine further evalution for future care.
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6/289. Honeymoon malaria and "herbal" therapy: A case report.

    A marked rise in the number of cases of malaria in the UK contracted in east africa has been reported in 1998. This may be explained by the "Lariam"-media hype, poor understanding, poverty of health education, or increase in travel to more exotic destinations. European centers have experienced changes in the pattern of imported malaria and constant up-dates are essential. However even the best informed may still acquire malaria.
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7/289. Transmission of malaria tertiana by multi-organ donation.

    In this report, transmission of malaria via a liver, a kidney, and possibly a heart allograft from a single donor is described. The donor had immigrated from cameroon to germany 18 months before, but had no clinical signs of active malaria infection. The liver transplant recipient and one of the two kidney transplant patients developed febrile illness with the appearance of plasmodium vivax in blood smears 5 and 6 wk after transplantation, respectively. In the heart transplant recipient, a subclinical malaria infection was suspected based on a rise of malaria antibodies late after transplantation, whereas the recipient of the second kidney allograft had no clinical or laboratory evidence of malaria. Both liver and kidney recipients with active malaria responded to medical treatment. However, the liver transplant patient developed progressive cholestasis and died 5 months after transplantation from liver failure possibly due to side effects of the malaria medication. Other cases of malaria in solid organ recipients are briefly reviewed.
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8/289. Malaria complicating neoplastic disease.

    Two patients with neoplastic disease had transfusion-induced malaria. In a patient with acute myelogenous leukemia infected with plasmodium vivax, neither his underlying disease nor intensive cytotoxic chemotherapy appeared to ameliorate or worsen the clinical course of his infection. In a splenectomized patient with metastatic carcinoma of the colon, P malariae infection was associated with a fulminant course simulating cerebral malaria. Despite delay in diagnosis, both patients responded dramatically to antimalarial chemotherapy and both developed appreciable antibody responses.
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9/289. Erythrocyte Fy antigen phenotyping helps differentiate so-called benign tertian malarias.

    Isolated cases of malaria are increasing in frequency in nonendemic countries. Blood film examination remains a mainstay of diagnosis of these sporadic cases because immunologic and molecular methods are unavailable, expensive, and problematic. Two tertian malarial species, plasmodium vivax and plasmodium ovale, may appear to be similar morphologically. plasmodium ovale infection is infrequent, and misdiagnosis of this species is common. plasmodium vivax infection can be ruled out, however, if a patient's erythrocytes phenotype as Fy(a-b-), because these cells completely resist entry by the latter species.
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10/289. plasmapheresis in the treatment of tropical malaria.

    A case of tropical malaria imported from kenya was described. plasmodium falciparum (an etiological agent of this disease) is often drug resistant, therefore pharmacological treatment of the patients was supplemented with plasmapheresis. Full recovery has been achieved. It is suggested that plasmapheresis may be recommended for a complex therapy of severe forms of tropical malaria.
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