Cases reported "Metaplasia"

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11/21. Necrotizing sialometaplasia. A self-limited pseudotumoral palatal ulcer.

    Necrotizing sialometaplasia of the palate, an enigmatic pseudomalignant penetrating ulcer, is a benign lesion which heals spontaneously in three to ten weeks. Relative painlessness contributes to patient delay in seeking medical attention, and suggest that many cases are subclinical. Clinically, the patient age group and morbid gross appearance mimic malignant palatal tumors. Lack of awareness of this entity has led to the misdiagnosis of carcinoma in several previous cases. However, the histopathologic features of sialadenitis, focal lobular necrosis with mucosal ulceration and glandular squamous metaplasia, are distinctly benign. A typical case and literature review are presented.
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ranking = 1
keywords = sialometaplasia
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12/21. Necrotizing sialometaplasia in a patient with Buerger's disease and Raynaud's phenomenon.

    This report describes a case of necrotizing sialometaplasia (NS) in a patient diagnosed as having Buerger's disease with secondary Raynaud's phenomenon. The danger of misdiagnosing NS as a malignant lesion is emphasized. Possible causal relationships between the patient's medical condition and the lesion are discussed.
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ranking = 1.1192707433742
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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13/21. Necrotizing sialometaplasia: literature review and presentation of five cases.

    Necrotizing sialometaplasia is a benign, ulcerative, inflammatory process of the minor salivary glands, primarily found in the hard palate. It is often mistaken clinically and histologically for a malignant tumor (that is, mucoepidermoid or squamous cell carcinoma). The lesion heals spontaneously in six to 12 weeks. It occurs primarily in persons between the ages of 40 and 60 and has been reported more frequently in men than women. In necrotizing sialometaplasia the squamous metaplasia and tissue necrosis is confined to the existing ductal and lobular pattern of the salivary glands, a unique characteristic that aids in diagnosis. Five additional cases are presented.
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ranking = 1.3192707433742
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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14/21. Warthin tumor exhibiting sebaceous differentiation and necrotizing sialometaplasia.

    A case of Warthin tumor exhibiting sebaceous differentiation and necrotizing sialometaplasia is presented. This case suggests a common histogenesis for the Warthin tumor and sebaceous lymphadenoma. It supports the theory that necrotizing sialometaplasia is caused by factors which compromise or obstruct the blood supply to salivary gland tissues. The literature on sebaceous differentiation in Warthin tumor and on necrotizing sialometaplasia is reviewed.
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ranking = 2.2348952036195
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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15/21. Necrotizing sialometaplasia in the setting of acute and chronic sinusitis.

    Necrotizing sialometaplasia is a benign lesion that may be mistaken for mucoepidermoid or squamous cell carcinoma. A case report is presented in which necrotizing sialometaplasia was noted as an incidental finding in the setting of acute and chronic sinusitis. It is critical to recognize the lesion as benign so as to avoid overdiagnosis and overtreatment.
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ranking = 1.3192707433742
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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16/21. Necrotizing sialometaplasia of the lip simulating squamous cell carcinoma.

    A case of necrotizing sialometaplasia of the lip in an 68-year-old pipe smoker is described. Necrotizing sialometaplasia is a self-healing non-neoplastic disease probably of ischaemic nature. Thirty-nine cases of sialometaplasia are described in the literature up to early 1979. These cases appeared in the palate, nasal cavity, gingiva, lip, hypopharynx and maxillary sinus. Six cases have also been reported from major salivary glands. Histologically there is necrosis of mucous cells with partial replacement by squamous epithelium. This entity has often been mistaken for squamous or mucoepidermoid carcinoma. One has to be familiar with the existence of necrotizing sialometaplasia in ordeg surgery.
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ranking = 1.8385414867484
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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17/21. Necrotizing sialometaplasia involving the nasal cavity.

    Necrotizing sialometaplasia is a disease process which affects minor salivary glands. It may clinically and microscopically resemble squamous cell or mucoepidermoid carcinoma but is histologically benign. Thirteen patients with this process occurring on the hard palate have been reported in the past two years. We describe two cases in the nasal cavity and propose that compromise of the blood supply contributed to the occurrence of these lesions. This apparently benign lesion may represent nonspecific reaction of salivary and mucous glands to ischemic injury and must be distinguished from carcinoma.
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ranking = 1
keywords = sialometaplasia
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18/21. Necrotizing sialometaplasia: a source of confusion with carcinoma of the palate.

    Necrotizing sialometaplasia is a self-healing nonneoplastic disease of the hard and soft palate characterized by one or two deeply excavating ulcers. Histologically, there is necrosis of the mucous cells of the minor salivary gland tissue with partial replacement by squamous epithelium. The deeply situated squamous epithelium intermixed with mucous cells may lead to the erroneous diagnosis of squamous carcinoma or mucoepidermoid carcinoma. The confinement of cytologically benign squamous epithelium to the pre-existing lobular pattern of the salivary gland should permit an accurate histologic diagnosis by biopsy and avert further surgical intervention.
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ranking = 1
keywords = sialometaplasia
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19/21. Necrotizing sialometaplasia involving the mucous glands of the nasal cavity.

    Necrotizing sialometaplasia was found in maxillary sinus mucous glands of an 83 year old woman who had undergone a radical maxillectomy for basal cell carcinoma 10 days earlier. Previously recognized as an ulcerating lesion involving salivary glands in the oral cavity, this benign reactive process may also occur in the mucous glands of the nasal cavity and sinuses and can simulate squamous cell or mucoepidermoid carcinoma. ischemia appears to be pathogenetic.
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ranking = 1
keywords = sialometaplasia
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20/21. Tumour-simulating squamous cell metaplasia (SCM) in necrotic areas of salivary gland tumours.

    Squamous cell metaplasia (SCM) adjacent to necrotic areas of salivary gland tumours must be distinguished from other types of SCM (focal SCM in the excretory ducts of salivary glands; necrotizing sialometaplasia; focal SCM within salivary gland tumours) in respect to the tissue structure. Based on the high cellular proliferation, arcade- or cord-like pseudoneoplastic SCM develops with stellate extension in the surrounding tissue and focal inclusion of goblet cell metaplasia. This proliferative SCM resembles the cellular demarcation of radicular dental cysts. In the Salivary Gland Register 8 cases of tumor-simulating SCM could be analysed which clinically and morphologically were suspect of squamous cell or mucoepidermoid carcinoma. Five cases were localized in the parotid gland, 2 cases in the submandibular gland and 1 case in the palatinal glands. Tumour-simulating SCM was developed in pleomorphic adenomas (5 cases) and in multifocal adenomatous oncocytic hyperplasia (3 cases).
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ranking = 0.31927074337421
keywords = sialometaplasia, necrotizing sialometaplasia, necrotizing
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