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1/3. Oral leishmaniasis in a hiv-positive patient. Report of a case involving the palate.

    leishmaniasis is a parasitic disease caused by a protozoon (Leishmania), with different clinical forms that are endemic in certain countries. The association of this disease in patients who are seropositive to human immunodeficiency virus (hiv) has recently been described. leishmaniasis can develop in any stage of hiv infection, although the clinical manifestations - and hence the diagnosis - tend to coincide with the periods of maximum immune depression. We present the case of a hiv-positive, ex-intravenous drug abuser (in stage B2 of the CDC, 1992) with concomitant hepatitis c infection who presented with palatinal pain and bleeding for the past 2 months. Exploration revealed a vegetating tumoration of the hard palate. hematoxylin-eosin and Giemsa staining of the biopsy confirmed the diagnosis of leishmaniasis. The definitive diagnosis was mucocutaneous leishmaniasis (MCL), for a bone marrow aspirate proved negative, and no further lesions could be established. The patient was treated with meglumine antimoniate (Glucantime), followed by improvement of the lesions.
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2/3. association of oral cysticercosis and post kala azar dermal leishmaniasis.

    Oral cysticercosis affecting the tongue in association with post kala azar dermal leishmaniasis in an adult man is presented. The features that helped to distinguish oral cysticercosis from other conditions endemic in that area are briefly discussed.
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keywords = leishmaniasis
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3/3. Oral mucosal leishmaniasis as a presenting feature of hiv infection and its management.

    leishmaniasis is a chronic parasitic protozoal disease transmitted by sandfly vectors and is endemic in some regions of south america, asia, africa and Mediterranean countries. This case report describes a British patient who presented with oral mucosal leishmaniasis and in whom it was also the first sign of hiv disease. We believe it is the first reported case of isolated oral mucosal leishmaniasis as a presenting feature of otherwise unknown hiv infection.
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keywords = leishmaniasis
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