Cases reported "Muscle Neoplasms"

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1/4. Extradigital glomus tumor causing para-achilles tendon pain. A case report.

    A 48-year-old woman with a 15-year history of a painful nodule in the para-achilles tendon area was evaluated by clinical examination, magnetic resonance imaging and ultrasonography, then treated by simple surgical excision of the nodule. pathology revealed a glomus tumor, which is extremely rare in the para-achilles tendon area. This is the first report of a glomus tumor in this location.
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2/4. Malignant glomus tumor in the branchial muscle of a 16-year-old girl.

    Malignant glomus tumor is an extremely rare neoplasm and its histological features are not well characterized. We report a 16-year-old female patient with a malignant glomus tumor. The patient was admitted to our hospital presenting with a mass in the right upper arm that she had noticed for the previous 6 months. Computed tomography and magnetic resonance imaging revealed an expanded mass involving the surrounding tissues. At surgery, an ill-defined and expanded mass was found, 5 x 4 x 3 cm in size, in the right branchial muscle. The tumor was extirpated, along with neighboring muscle tissues. Histologically, tumor cells were round to short-spindle shaped, forming solid sheets admixed with vessels of varying size. Their nuclei were uniformly oval to round, and their cytoplasms were slightly eosinophilic. The growth pattern of the tumor cells resembled that of glomus tumor, but mitotic figures were frequent (as high as 10 per 10 high-power fields). Immunohistochemically, the tumor cells were positive for vimentin and muscle actin, but negative for desmin. There were no areas typical of benign glomus tumor or sarcomatous change. These findings led us to a diagnosis of primary malignant glomus tumor arising de novo. There has been no recurrence or metastasis for 21 months after wide excision.
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keywords = glomus
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3/4. Glomangioma of the ankle simulating injury to the flexor hallucis longus: a case report.

    The glomangioma is one of a group of benign tumors of glomus body origin. Commonly found in the distal extremities, they may present with pain, tenderness to palpation, and sensitivity to temperature. Histologically, varying proportions of glomus cells, as well as vascular and smooth muscle elements, are found. Complete surgical excision is usually curative. We report on a glomangioma of the ankle in a 12-year-old male patient that simulated injury to the flexor hallucis longus tendon.
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keywords = glomus
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4/4. glomus tumor with diffuse infiltration of the quadriceps muscle: a case report.

    A case of a diffuse growing glomus tumor with interstitial infiltration of the musculus vastus medialis and intermedius (quadriceps muscle) in a 21-year-old woman is reported. The tumor was diagnosed by needle biopsy and then removed with wide margins. The typical histological appearance and the immunohistochemical findings in the resected specimen confirmed the diagnosis. Histogenesis and the biological behavior of glomus tumors are discussed.
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keywords = glomus
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