Cases reported "Mycoses"

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11/23. fusarium solani osteomyelitis with probable nosocomial spread.

    A case of fusarium solani osteomyelitis is reported in a previously healthy adult male who received multiple injuries during an automobile accident. Combined histologic and mycologic data proved it to be a case of hyalohyphomycosis resulting from fusarium. To the best of the authors' knowledge, this is the first reported case of osteomyelitis resulting from F. solani. A concurrent case of saprophytic wound colonization by the same organism is reported in another patient in the same ward who had sustained similar injuries. Evidence suggests that this represents nosocomial spread from the first case.
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ranking = 1
keywords = wound
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12/23. Phaeohyphomycotic cyst caused by a recently described species, Phaeoannellomyces elegans.

    An 81-year-old man presented with a chronic, painful nodule on the palmar surface of the left fourth finger. As a former farm worker, the patient acknowledged frequent soil-contaminated wounds of the left hand 4 to 12 years previously, but he denied any recent trauma. The patient's other medical problems included a history of chronic immunoglobulin a gammopathy and a new pleural mass eroding into adjacent ribs on chest X-ray. The finger nodule was excised and consisted of an intact phaeohyphomycotic cyst which yielded growth of a darkly pigmented fungus. At 25 degrees C, the isolate formed annellidic yeast cells having dark-brown walls consistent with the recently described species Phaeoannellomyces elegans. in vitro antifungal susceptibility tests indicated resistance to amphotericin b and variable susceptibility to imidazoles. The lesion was excised, and the patient received no antifungal therapy. After 9 months of follow-up, the fungal infection shows no signs of recurrence.
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ranking = 1
keywords = wound
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13/23. Phialemonium obovatum infection in a burned child.

    Phialemonium obovatum is reported for the first time as an opportunistic fungal pathogen of man. The fungus was recovered from biopsy specimens consisting of cutaneous and subcutaneous tissue obtained from thermal burn wounds antemortem and from spleen tissue and three burn sites postmortem. The hyaline hypae of P. obovatum were seen invading viable tissue and blood vessels. The taxonomy of the genus Phialemonium and the criteria for determining fungal burn wound invasion are discussed.
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ranking = 2
keywords = wound
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14/23. Clinical significance of pseudallescheria boydii: a review of 10 years' experience.

    pseudallescheria boydii is a recognized cause of mycetoma, a chronic fungal disease that usually affects the extremities. Isolated case reports have also implicated P. boydii in infections of other sites. We report the first large series (83 isolates) of P. boydii in 46 patients, including the second report of P. boydii brain abscess and disseminated infection in a noncompromised host. Between 1974 and 1984 at our institution, P. boydii was cultured from a variety of sites: respiratory tract, 36; soft tissue, 25; bone, 9; gastric aspirate, 4; maxillary sinus, 2; wound, 2; urine, 2; brain abscess, 1; ear, 1; and toenail, 1. Pulmonary colonization proved to be the most common form of pseudallescheriasis of the lung (34 of 36 cultures in this category); 28 of the 32 patients with pulmonary infections had received immunosuppressive therapy or had an underlying disorder. The importance of isolation of P. boydii from bone and soft tissue is supported in this series because all 9 cultures from bone and 21 of 25 cultures from soft tissue were associated with infection. Of 10 cases of infection, 5 were osteomyelitis and 2 were infected wounds; in addition, maxillary sinusitis, disseminated infection, and a lung abscess occurred in 1 patient each.
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ranking = 2
keywords = wound
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15/23. Post-craniotomy wound infection caused by pseudallescheria boydii. Case report.

    The authors describe the first reported case of post-craniotomy wound infection due to pseudallescheria boydii. The patient was a 24-year-old man who sustained a direct blunt injury to the calvaria, resulting in a large subdural hematoma that was surgically evacuated. Subsequently, the surgical wound became infected with a fungus, P. boydii, and was successfully treated with intravenous miconazole.
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ranking = 605.87073106822
keywords = wound infection, wound
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16/23. Impalement injuries.

    Impalement injuries are unusual, complex surgical problems. We present a case of impalement through the spine and abdomen, describe a two-team approach to operative extraction utilizing simultaneous laminectomy and laparotomy incisions, and outline the management of an infectious complication caused by unusual bacterial and fungal pathogens. General principles of management include: the impaling object must be stabilized and manipulation avoided during extrication and transport. Operative removal requires careful preplanning, and should be tailored to the specific presenting injuries, with early multispecialty involvement as necessary. Extensive exposure is mandatory and may be achieved through a variety of standard or unconventional incisions so as to permit extraction of the impaled object under direct vision. Meticulous care of the traumatic wound is necessary, and careful followup is required for recognition and early management of infectious complications.
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ranking = 1
keywords = wound
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17/23. fusarium infection in burned patients.

    The incidence of fungal infections of burn wounds is increasing because of the dramatic improvement in antibacterial chemotherapy and burn wound care. Species of fusarium, common soil fungi and plant pathogens, are rarely isolated from burn wounds, and invasive disease due to these organisms is also rare. Therefore, a case of burn wound infection with dissemination due to F. oxysporum is reported; three other cases of burn wound colonization by fusarium sp. are also reported. The literature on fungal infections of burn wounds is reviewed, and the importance of combined histologic and mycologic studies in the evaluation of such wounds is discussed.
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ranking = 126.97414621364
keywords = wound infection, wound
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18/23. Fungal sternal wound infection due to Curvularia lunata in a neonate with congenital heart disease: case report and review.

    We describe a neonate with congenital heart disease in whom a sternal wound infection caused by the filamentous fungus Curvularia lunata developed following cardiac surgery. Despite their widespread distribution in the environment, Curvularia species rarely cause human infection. We also review the 43 cases of curvularia infection previously reported in the English-language literature; only four of these cases occurred in children. A wide spectrum of infections--including keratitis, cutaneous infections, sinusitis, allergic bronchopulmonary disease, pneumonia, chronic ambulatory peritoneal dialysis-related infections, endocarditis and disseminated infections--have been described. Curvularia is a pathogen that can cause disease in both immunocompetent and immunocompromised hosts, although more severe and disseminated disease occurs in patients with defective immune function. Surgery alone usually is successful for treating locally invasive disease, although a combination of medical and surgical therapy is necessary for treating disseminated infections.
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ranking = 604.87073106822
keywords = wound infection, wound
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19/23. Invasive burn wound infection due to Curvularia species.

    A 3-year-old white-skinned female sustained a 44 per cent deep partial and full skin thickness burn due to petrol. She developed an invasive wound infection due to a fungus later identified as Curvularia species, an organism, usually a saprophyte, not previously reported as a cause of invasive burn wound infection. Treatment with surgical excision and amphotericin b resulted in cure.
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ranking = 725.84487728186
keywords = wound infection, wound
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20/23. Fatal systemic mycotic infections in the burned child.

    Two cases of systemic phycomycotic burn wound infection occurred in severely burned children. Both patients, although treated aggressively, died after systemic colonization through the burn wound by fungi. Modern burn therapy has increased survival of many severely burned children but opportunistic fungal infection remains as an ominous threat. Early recognition, wide excision or amputation, and systemic antifungal agents comprise the current clinical armamentarium against systemic fungal invasion of burn wounds.
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ranking = 122.97414621364
keywords = wound infection, wound
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