Cases reported "Nail Diseases"

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1/13. hydroxyurea-induced melanonychia concomitant with a dermatomyositis-like eruption.

    We describe the cases of 7 patients with hydroxyurea-induced melanonychia. In two of the patients, a dermatomyositis-like eruption was also present.
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keywords = eruption
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2/13. Reticulate and stellate acral pigmentation associated with systemic lupus erythematosus and high titers of circulating anticardiolipin antibodies: a possible association with acral microlivedo.

    A Hispanic man with a twenty-eight year history of systemic lupus erythematosus (SLE) and a high titer of anticardiolipin IgG antibodies was noted to have reticulate and stellate acral pigmentation. The patient reported that hand swelling and erythema developed soon after the diagnosis of SLE was established. This episode resolved quickly without recurrence or immediate sequelae. We postulate that this eruption was related to SLE and anticardiolipin antibodies. Reticulate and stellate acral pigmentation should be considered a possible manifestation of SLE and high titers of anticardiolipin antibodies, or a consequence of therapy.
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keywords = eruption
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3/13. Oral-dental findings in dyskeratosis congenita.

    A 13-yr-old girl with dyskeratosis congenita is presented. Besides oral leukoplakia and nail dystrophies, there was evidence of pancytopenia, growth retardation, alopecia, mental retardation and microcephaly. The oral findings included caries, gingival recession, short-blunted roots, gingival bleeding, tooth mobility and severe alveolar bone loss resembling juvenile periodontitis.
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ranking = 0.029027332637348
keywords = tooth
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4/13. A case of crusted scabies with a bullous pemphigoid-like eruption and nail involvement.

    We report a case of a 71-year-old man infected at a nursing home who developed a bullous pemphigoid-like eruption with nail involvement. He was diagnosed by his family doctor as suffering from eczema and was treated with topical corticosteroids, then blisters started appearing. He was next diagnosed as suffering from bullous pemphigoid and treated with oral prednisolone, which worsened his condition. He was finally diagnosed as having crusted scabies with bullous pemphigoid-like eruptions and nail involvement at our clinic. He was then prescribed oral ivermectin (two doses of 12 mg ivermectin with a 1-week interval) and topical lindane (1%gamma-BHC in petrolatum) for scabies with 5% salicylic acid in plastibase as an additional treatment for the crusted lesions on his soles. He showed remarkable improvement in 2 weeks, and his nails showed complete recovery after 7 weeks of occlusive dressing treatment with 1%gamma-BHC. One and a half years later, the patient showed no sign of a recurrence of scabies. The histology of a blister taken from this patient was similar to that of bullous pemphigoid. Direct immunofluorescence showed immunoglobulin (Ig)G and C3 deposition at the dermoepidermal junction similar to that of bullous pemphigoid, but indirect immunofluorescence was negative. The bullous symptoms of this patient were considered to be due to the scabies, because the patient recovered completely after receiving treatment for scabies. Indirect immunofluorescent study is important to distinguish between scabies with blister formation and true bullous pemphigoid.
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ranking = 1.2
keywords = eruption
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5/13. Fixed-drug eruption presenting as an acute paronychia.

    A case of fixed-drug eruption due to cefalexine presented with acute paronychia. Twenty days after a further challenge with a single dose of the drug, a biopsy of the affected skin showed intense expression for ICAM-1.
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keywords = eruption
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6/13. onychomycosis in graft versus host disease.

    Graft versus host disease is associated with a myriad of cutaneous signs and few nail manifestations. A case of documented chronic graft versus host disease with the initial cutaneous presentation of white superficial onychomycosis is presented. The patient developed a lichenoid eruption in an unusual distribution and a reticulated hyperpigmentation of the face. culture of the nails was positive for trichophyton rubrum, an uncommon cause of white superficial onychomycosis, this being the third known reported case. Histopathologic examination revealed fungal elements in the superficial nail plate with an absence of fungus in the ventral aspect of the nail plate. A summary of cutaneous skin and nail manifestations in graft versus host disease is presented.
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keywords = eruption
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7/13. minocycline hyperpigmentation: skin, tooth, nail, and bone involvement.

    The association of bone, tooth, nail and scleral pigmentation in a patient treated for acne with minocycline was noted. hyperpigmentation appeared in old scar tissue, but not that present from recent surgical procedures.
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ranking = 0.14513666318674
keywords = tooth
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8/13. Lichen striatus with onychodystrophy.

    Two case reports of lichen striatus with nail dystrophy are presented herein. review of the literature suggests a more protracted course for the cutaneous eruption if there is nail involvement. biopsy is important to differentiate this condition from other linear lesions that may interfere with normal nail growth.
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ranking = 0.2
keywords = eruption
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9/13. lichen planus with predominant plasma cell infiltrate.

    We herein report the case of a patient with lichenoid plaques on the lower extremities and anonychia of all toenails. Histologically, the eruption showed typical features of lichen planus, with the exceptional finding of a lichenoid infiltrate composed mostly of plasma cells. Only two other similar cases have been reported. The explanation for the numerous plasma cells remains unknown although such cases may represent a new histologic variant.
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ranking = 0.2
keywords = eruption
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10/13. Bazex's syndrome (acrokeratosis paraneoplastica)--first case report of association with a bladder carcinoma.

    Bazex's acrokeratosis paraneoplastica is a clinically well-defined entity consisting of a distal erythemato-squamous eruption and nail dystrophy. It is always associated with neoplasia, mainly squamous carcinomas of the upper digestive and respiratory tracts; therefore, Bazek's acrokeratosis is considered to be a specific marker of internal malignancy. Two new cases of this syndrome are reported. The first was in a 41-year-old man with a squamous cell carcinoma of the oesophagus, the second in a 73-year-old man who presented with a transitional cell bladder carcinoma, an association not previously reported.
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ranking = 0.2
keywords = eruption
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