Cases reported "Nematode Infections"

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1/3. Human gnathostomiasis.

    Two patients became infested with gnathostoma nipponicum after eating raw loach-fish they had caught in a rice field in central japan. A fragment of gnathostoma was found in a biopsy from one of them. The sera of both patients reacted with gnathostoma antigen using indirect immunofluorescence. Scanning electron microscopy was performed on blocks of the paraffin-embedded parasite sample and the viscera of a fish from the same rice field. The risk of eating raw freshwater fish is discussed.
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2/3. Two human cases of gnathostomiasis and discovery of a second intermediate host of gnathostoma nipponicum in japan.

    Two human cases of gnathostomiasis from ingestion of raw native Japanese loaches, Misgurnus anguillicaudatus, are reported. Seven early third-stage larval gnathostoma nipponicum were recovered from 3,098 loaches in the same district in which 2 human patients had obtained and eaten raw loaches. Encapsulated G. nipponicum larvae were also recovered from loaches infected under laboratory conditions. All 6 weasels captured in the same district in which the naturally infected loaches were found and where the humans had become infected were infected with adult worms of the same species. This is the first report of M. anguillicaudatus serving as a second intermediate host of G. nipponicum.
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3/3. Eosinophilic meningoradiculomyelitis caused by gnathostoma spinigerum. A case report.

    A 51-year-old man had excruciating pains in the left arm and chest approximately four weeks after ingestion of live loaches. eosinophilia, eosinophilic pleocytosis in the CSF, and a high serum IgE level were noted. skin tests and antigen-antibody reactions were positive for gnathostoma infection. His clinical signs and symptoms ameliorated with symptomatic treatment within six months. Only 34 cases of gnathostomiasis involving the CNS have been reported in the English literature, and ours is the first Japanese case, to the best of our knowledge, of eosinophilic meningoradiculomyelitis caused by gnathostoma spinigerum.
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