Cases reported "Opportunistic Infections"

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11/23. A rare presentation of zygomycosis (mucormycosis) and review of the literature.

    zygomycosis (mucormycosis) is a rare fungal infection seen most often in association with prolonged neutropenia. Intestinal zygomycosis is extremely rare and difficult to diagnose, but it is important not to miss, because early medical and surgical treatment can improve survival. This report describes a 56 year old woman who developed this infection while receiving chemotherapy for acute lymphoblastic leukaemia. Medical and surgical measures proved unsuccessful because there was a delay in diagnosis and institution of appropriate treatment.
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keywords = zygomycosis
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12/23. Successful treatment of rhinocerebral zygomycosis with a combination of caspofungin and liposomal amphotericin b.

    Genera of the order mucorales (rhizopus, Mucor, rhizomucor, absidia, Apophysomyces, cunninghamella, and Saksenaea) cause an angioinvasive infection called zygomycosis. mortality rates can approach 100% depending on the patient's underlying disease and form of zygomycosis. We report here on the unusual case of a patient with acute myelogenous leukemia and zygomycosis unresponsive to monotherapy with liposomal amphotericin b, who responded favorably following the addition of the echinocandin caspofungin acetate.
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ranking = 1.4
keywords = zygomycosis
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13/23. Endobronchial zygomycosis.

    Pulmonary zygomycosis is an uncommon opportunistic fungal infection. Diabetics have a tendency to develop major airway lesions. This can lead to invasion of the airway wall and hilar vessels with infarction and severe haemoptysis. Aggressive early surgery appears to offer the best chance of recovery.
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keywords = zygomycosis
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14/23. zygomycosis (absidiomycosis) in an AIDS patient. Absidiomycosis in AIDS.

    absidia corymbifera is rarely cited as a cause of zygomycosis in the human host. Presented here is a case of absidiomycosis in a 29 year old construction worker hospitalized with a 6 year of intravenous drug abuse, serological evidence for hiv infection, and the symptomatology of AIDS. A CT scan and gallium uptake imaging identified a nonfunctioning right kidney. Following a biopsy and a nephrectomy, histopathology revealed hyphal components consistent with zygomycosis. culture of the biopsy and surgical specimens yielded A. corymbifera. Clinically the patient responded well to amphotericin b therapy.
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ranking = 0.4
keywords = zygomycosis
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15/23. cauda equina syndrome secondary to disseminated zygomycosis.

    We describe a case of cauda equina syndrome secondary to disseminated zygomycosis. A 52-year-old man had myelodysplastic syndrome, progressive weakness of the lower extremities, and incontinence. Neuroradiological findings were consistent with lumbar stenosis and probable disk herniation. A lung lesion was also discovered on the chest roentgenogram. The patient's condition rapidly deteriorated after surgical decompression. Attempts at determining other etiologies were unsuccessful. At autopsy, disseminated zygomycosis was found affecting the lung and the vasculature of the cauda equina and lumbosacral nerve roots, with resultant focal demyelination of these structures. Ribbon-like hyphal elements were also present in the caudal roots. This opportunistic pathogen is discussed along with the diagnostic challenge presented by its unusual clinical presentation.
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ranking = 1.2
keywords = zygomycosis
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16/23. myocardial infarction caused by cardiac disease in disseminated zygomycosis.

    A case of disseminated zygomycosis is described, in which myocardial infarction rather than coincident coronary or heart disease was seen at necropsy. As zygomycosis is an opportunistic fungal infection, which tends to invade blood vessels, thereby causing thrombosis and infarction, it is surprising that cardiac disease is unusual and that premortem evidence of such disease has only rarely been reported.
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ranking = 1.2
keywords = zygomycosis
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17/23. zygomycosis due to Mucor circinelloides in a neutropenic patient receiving chemotherapy for acute myelogenous leukemia.

    Mucor circinelloides form circinelloides has rarely been associated with human disease, even in immunocompromised patients. We report a case of cutaneous zygomycosis caused by M. circinelloides in a 23-year-old neutropenic woman receiving consolidation chemotherapy for acute myelogenous leukemia. The organism was exquisitely susceptible to amphotericin b. Despite the fact that the patient was profoundly neutropenic for an additional 3 weeks, the lesions began to resolve during therapy, and no surgical debridement was required.
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ranking = 0.2
keywords = zygomycosis
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18/23. fluconazole in the treatment of pulmonary zygomycosis.

    Pulmonary zygomycosis is an aggressive, often terminal infection that may be found in patients who are immunocompromised as a result of cytotoxic chemotherapy. Conventional treatment is by surgical debridement augmented with high-dose intravenous amphotericin b, but even with such treatment the course is usually fulminant with a high mortality rate. Recent work has suggested that the new antifungal triazole, fluconazole, may be of benefit in treating zygomycete infection. The case of a 15-year-old boy who developed pulmonary zygomycosis while on chemotherapy for acute lymphoblastic leukaemia, and who survived for 11 months with oral fluconazole therapy alone, is supportive of this proposal.
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ranking = 1.2
keywords = zygomycosis
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19/23. Locally invasive oral candidiasis mimicking zygomycosis in a patient with diabetic ketoacidosis.

    candida species are increasingly assuming a pathogenic role in patients throughout the spectrum of in competence. This case history documents a unique presentation of candidiasis with marked similarity to the zygomycoses in patients with diabetic ketoacidosis and explores the pathogenetic basis for both.
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ranking = 0.8
keywords = zygomycosis
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20/23. Rhinocerebral zygomycosis.

    An unusual case of rhinocerebral zygomycosis with its clinical and histopathological features are presented. A good response was observed with oral itraconazole at a dose of 200 mg day-1 for a period of 3 months. To our knowledge, it is the first case report of this infection, involving the maxillary sinus, eye and the brain, from Madras, Tamilnadu, india.
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ranking = 1
keywords = zygomycosis
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