Cases reported "Oral Ulcer"

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1/3. Mucocutaneous leishmaniasis in a US citizen.

    Mucocutaneous leishmaniasis (MCL) is endemic to many areas of Central and south america. A case of MCL in a US citizen is reported here. An ulcer appeared on the patient's left hard palate, years after a working trip to peru. Punch biopsies of the lesion were obtained, Leishmania promastigotes were isolated by culture and animal inoculation, and the patient was appropriately treated. As this case demonstrates, a patient's travel history is a key element in making a differential diagnosis of oral lesions.
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ranking = 1
keywords = leishmaniasis
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2/3. Visceral leishmaniasis and hiv co-infection: a rare case of pulmonary and oral localization.

    Visceral leishmaniasis (VL) has increased as a complicating infection in subjects with human immunodeficiency virus (hiv) in countries bordering the Mediterranean sea. The clinical course as well as organ involvement of VL are often atypical in hiv positive subjects. In this study a case of VL with pulmonary and oral mucose localisation in a patient with acquired immune deficiency syndrome (AIDS), is reported. These findings, together with the presence of the parasite in the peripheral blood smear, confirm that in hiv positive patients the impaired immune system allows the spreading and the atypical localisation of the Leishmania amastigotes more easily than in immuno-competent individuals. In endemic areas and in hiv positive subjects a systemic and careful parasitological follow-up is necessary to ensure that any clinical form of leishmaniasis is not overlooked.
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ranking = 1.2
keywords = leishmaniasis
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3/3. Imported mucocutaneous leishmaniasis.

    We report a case of mucocutaneous leishmaniasis in a otherwise fit Caucasian man who had traveled in an endemic area. Initial tissue microscopy failed to identify the causative organism, which was only determined by subsequent culture as leishmania braziliensis. This case illustrates the variability in the presence of Leishman-Donovan (LD) bodies in histopathological studies and emphasizes the need for culture in suspected cases of leishmaniasis, particularly given the ability of certain Leishmania species such as L. braziliensis to cause recalcitrant and destructive infections of the nose and mouth.
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ranking = 1.2
keywords = leishmaniasis
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