Cases reported "Orchitis"

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1/6. Epididymo-orchitis following intravesical bacillus Calmette-Guerin therapy.

    OBJECTIVE: To describe a case of epididymo-orchitis that developed four years after treatment with intravesical bacillus Calmette-Guerin (BCG) and to review the incidence of this adverse effect. DATA SOURCES: Information about the patient was obtained from the medical chart. A medline search of English-language literature (from January 1976 to April 1999) was conducted. STUDY SELECTION: All case reports of BCG-related epididymo-orchitis were evaluated. review articles describing complications of BCG therapy for bladder cancer and the prevention and treatment of these complications were reviewed. DATA EXTRACTION: Studies were evaluated for reports of BCG-related epididymo-orchitis and its treatment. DATA SYNTHESIS: Our case report is compared with others reported in the literature. The incidence of BCG-associated epididymoorchitis is rare. CONCLUSIONS: Epididymo-orchitis should be considered as a late complication of BCG therapy for bladder cancer. Proper patient selection may help decrease the risk of complications from BCG therapy.
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ranking = 1
keywords = bacillus
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2/6. Epididymo-orchitis developing as a late manifestation of intravesical bacillus Calmette-Guerin therapy and masquerading as a primary testicular malignancy: a report of 2 cases.

    In 2 cases epididymo-orchitis, indistinguishable from a testicular tumor, developed as a late (15 and 34 months, respectively) complication following use of Tice strain bacillus Calmette-Guerin for treatment of superficial bladder carcinoma. In each instance the lesion was asymptomatic and ultrasonography demonstrated a complex scrotal mass. Inguinal orchiectomy was performed for diagnosis and therapy. The importance of obtaining a mycobacterial culture for further therapy planning is stressed.
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ranking = 1
keywords = bacillus
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3/6. Epididymo-orchitis caused by intravesically instillated bacillus Calmette-Guerin: genetically proven using a multiplex polymerase chain reaction method.

    The intravesical instillation of bacillus Calmette-Guerin (BCG) is a standard therapy for superficial bladder carcinoma. Tuberculosis-like inflammation in the genitourinary tract is a serious complication of BCG. It can occur after a long interval from the cessation of the intravesical BCG therapy. If inflammation occurs, it is necessary to test whether the BCG strain has caused it or another mycobacterium species has. However, there has never been a report that proves BCG causes the inflammation, because BCG is difficult to differentiate from other strains of mycobacterium bovis and other members of the mycobacterium tuberculosis complex by conventional tests, including regular polymerase chain reaction (PCR). We first present a case of epididymo-orchitis, which developed 31 months after the cessation of BCG therapy, detected using a multiplex PCR method as having been caused by BCG. Our report illustrates the efficacy of this method to detect the responsible microbe that is thought to be transmitted from the instillated BCG strain.
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ranking = 1.0127389738536
keywords = bacillus, mycobacterium
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4/6. Granulomatous disease of the testis.

    Granulomatous disease of the testis may have a specific cause or it may be idiopathic. We found 3 specific agents as the cause of the disease in a retrospective review of 17 cases of granulomatous disease of the testis. mycobacterium tuberculosis was the most common cause of subsequent granulomatous orchitis. The clinical presentations of the patients varied but several clues often were present that led to the diagnosis of granulomatous reaction. The patients were treated with orchiectomy. The acid-fast lipid of the tubercle bacillus and spermatozoa is suggested as a possible common denominator in the pathogenesis of the granulomatous reaction.
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ranking = 0.2
keywords = bacillus
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5/6. melioidosis presenting as epididymo-orchitis.

    We report a rare case of suppurative epididymo-orchitis caused by pseudomonas pseudomallei in a 56-year-old male. This is a gram negative bacillus found mainly in tropical zones. diagnosis was reached by culture of the organisms after drainage of the scrotal abscess, and the patient was treated by a course of oral chloramphenicol 500 mg qid for 6 months.
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ranking = 0.2
keywords = bacillus
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6/6. Epididymo-orchitis and Reiter's disease. Two infrequent complications after intravesical bacillus Calmette-Guerin therapy.

    Two cases of adverse reactions to intravesical treatment with bacillus Calmette-Guerin are reported. The first patient presented with a severe suppurating epididymo-orchitis three months after his last treatment. The second patient developed Reiter's disease with arthritis of one knee and conjunctivitis 1 week after the fourth instillation.
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ranking = 1
keywords = bacillus
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