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1/2. Idiopathic intracranial hypertension following kidney transplantation: a case report and review of the literature.

    A pediatric kidney transplant recipient receiving tacrolimus for immunosuppression experienced symptoms consistent with idiopathic intracranial hypertension. The diagnosis of idiopathic intracranial hypertension and possible secondary causes of intracranial hypertension are reviewed in association with the patient's clinical course. Treatment options for the reversal of intracranial hypertension are summarized. Because of the complexity of associated conditions in kidney transplant recipients, symptoms of persistent headaches, visual changes and nausea and vomiting should be promptly investigated by fundoscopic examination in the setting of immunosuppression therapy to prevent vision loss. ( info)

2/2. Diabetes in overweight pediatric patients.

    diabetes mellitus (DM) is a growing problem among youth. Although type 1 (insulin-dependent) DM is a disease typically diagnosed during childhood or adolescence, estimates indicate that < or = 45% of new diabetes cases in children are type 2. Children with new-onset type 2 DM are often overweight, aged 10 years or older, have a family history of the disease, and are members of a racial/ethnic minority group. DM treatment has progressed greatly in recent decades. Inadequate therapy, urine testing, glycosylated hemoglobin levels of >10%, and high rates of diabetic complications that were common in the past have yielded to more effective treatments, accurate monitoring, and better outcomes. insulin pumps and insulin analogues represent promising new avenues that have enhanced convenience, cost-effectiveness, patient satisfaction, and metabolic control of childhood DM. ( info)


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