Cases reported "Palatal Neoplasms"

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1/11. Necrotizing sialometaplasia.

    Three cases of necrotizing sialometaplasia of minor salivary glands are presented. Clinically and pathologically, this nonneoplastic lesion of the palate can be easily mistaken for carcinoma. The main histologic features are localized infarction of minor salivary glands and extensive squamous metaplasia with retention of the lobular architecture of the involved glands. The possible etiologic factors are discussed.
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ranking = 1
keywords = necrotizing sialometaplasia, sialometaplasia, necrotizing
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2/11. Angiocentric T-cell lymphoma presenting as midface destructive lesion: case report and literature review.

    A case of angiocentric T-cell lymphoma presenting as a midface destructive lesion is reported. Angiocentric T-cell lymphoma typically manifests as an aggressive, progressively destructive, and necrotizing disorder, often with a fatal outcome. This case was characterized microscopically by the presence of an atypical lymphoid population that expressed a CD45 , CD3 cytoplasmic, CD5 , and CD56- T-cell phenotype within a background of a polymorphous inflammatory infiltrate. Because of the rarity of the disorder, the differential diagnosis is discussed. Recent advances in clinical immunodiagnostics, the variations in therapeutic modalities, and the prognosis of the disease as reported in the recent literature are reviewed.
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ranking = 0.00011205978908158
keywords = necrotizing
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3/11. B-cell lymphoma presenting as a midfacial necrotizing lesion.

    A case of midfacial necrotizing lesion (midline nonhealing granuloma) is reported. paraffin- and frozen-section immunocytochemistry suggested a tumor of B-cell lineage and was confirmed by Southern blot analysis that disclosed an immunoglobulin heavy chain gene rearrangement with no evidence of T-cell receptor genetic aberration. The tumor was of B-cell lineage despite the tumor site and the angiocentric pattern, which are typically seen with peripheral T cell lymphoma with this presentation.
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ranking = 0.00056029894540791
keywords = necrotizing
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4/11. Necrotizing sialometaplasia associated with bulimia: case report and literature review.

    Necrotizing sialometaplasia (NSM) is a self-limiting disorder affecting mainly the minor salivary glands. The significance of NSM resides in its clinical and histopathological resemblance to carcinoma. Few cases of NSM associated with eating disorders have been reported to date. We present here the clinical features and histomorphology of an additional case of bulimia-associated NSM closely mimicking an invasive carcinoma. A high index of suspicion and good communication between clinician and pathologist are essential in recognizing this entity and preventing unnecessary surgical therapy.
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ranking = 0.82766681799094
keywords = sialometaplasia
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5/11. NECROTIZING SIALOMETAPLASIA.

    Nonhealing palatal ulcerations in two white male patients, one 50 and another 58 years of age, were clinically suspected of being malignant, even after the initial biopsies were negative. Second biopsies in each case confirmed the original opinions, but the lesions were diagnosed specifically as "necrotizing sialometaplasia". This is an interesting condition of uncertain etiology that can mimic cancer, both clinically and microscopically. The condition heals spontaneously. It should be considered in a differential diagnosis of suspicious lesions of the palate.
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ranking = 0.33786654560724
keywords = necrotizing sialometaplasia, sialometaplasia, necrotizing
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6/11. Necrotizing sialometaplasia of palate.

    A patient with necrotizing sialometaplasia of the hard palate was treated with wide resection on a biopsy diagnosis of carcinoma. The literature on this recently identified entity is reviewed and the characteristic clinical features, histopathology and ultrastructure are summarized. To the best of our knowledge, no ultrastructural study concerning this entity has been previously reported. Unless recognized early, an extensive resection might be done needlessly.
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ranking = 1
keywords = necrotizing sialometaplasia, sialometaplasia, necrotizing
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7/11. Asymptomatic, nonulcerated swelling of the posterior hard palate.

    It is very important for clinicians to understand that nonulcerated, firm, dome-shaped, nonpainful palatal swellings, if not inflammatory in nature, are probably arising in the palatal accessory salivary glands. The differential diagnosis must include benign mixed tumors; adenoid cystic carcinoma, and necrotizing sialometaplasia, which is usually ulcerated. Statistically, the possibility that the lesion is malignant is slightly greater than the possibility that it is benign. Incisional biopsy must be performed on these lesions to determine the proper treatment and management regimen.
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ranking = 0.33786654560724
keywords = necrotizing sialometaplasia, sialometaplasia, necrotizing
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8/11. Necrotizing sialometaplasia. A self-limited pseudotumoral palatal ulcer.

    Necrotizing sialometaplasia of the palate, an enigmatic pseudomalignant penetrating ulcer, is a benign lesion which heals spontaneously in three to ten weeks. Relative painlessness contributes to patient delay in seeking medical attention, and suggest that many cases are subclinical. Clinically, the patient age group and morbid gross appearance mimic malignant palatal tumors. Lack of awareness of this entity has led to the misdiagnosis of carcinoma in several previous cases. However, the histopathologic features of sialadenitis, focal lobular necrosis with mucosal ulceration and glandular squamous metaplasia, are distinctly benign. A typical case and literature review are presented.
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ranking = 0.82766681799094
keywords = sialometaplasia
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9/11. Necrotizing sialometaplasia of the palate. Ulcerative or necrotizing stage of leukokeratosis nicotina palati?

    A typical case of the recently described tumor-suspect lesion, necrotizing sialometaplasia (NS) of the palate, in a 54-year old Caucasian male is presented. Results of complete blood- and urinanalysis including serum electrophoresis and labial salivary gland biopsy strongly pointed at a local etiologic factor. Previous statements that the disease represents a new entity are questioned. The present authors favor the idea that NS is the necrotizing (ulcerative) or terminal stage of leukokeratosis nicotina palati (nicotinic stomatitis). It is of particular importance that this lesion is not diagnosed as a malignancy, as it heals spontaneously and uneventfully.
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ranking = 1.0005602989454
keywords = necrotizing sialometaplasia, sialometaplasia, necrotizing
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10/11. Necrotizing sialometaplasia: literature review and case reports.

    The authors describe necrotizing sialometaplasia, a benign inflammatory lesion primarily involving the minor salivary glands of the hard palate. The lesion presents itself as a deep-seated palatal ulcer with clinical and histologic features mimicking those of a malignant neoplasm. The lesion is believed to be the result of vascular ischemia initiated by trauma. An incisional biopsy is required to confirm the diagnosis, and the lesion heals by secondary intention within four to 10 weeks.
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ranking = 1
keywords = necrotizing sialometaplasia, sialometaplasia, necrotizing
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