Cases reported "Periodontal Diseases"

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21/87. rothmund-thomson syndrome: a case report.

    rothmund-thomson syndrome (RTS) is an extremely rare genetic disorder characterized by poikilodermatous skin changes, photosensitivity, and an increased risk of developing skin and bone malignancies. In this case report, the dental and periodontal features of RTS in a 16-year-old female patient are presented. The transmission electron microscopy performed on a gingival biopsy specimen showed structural defects of connective tissue. If the unusual ultrastructural findings of this case are confirmed as being consistent with other RTS patients, it is our opinion that this syndrome can be considered among the systemic diseases associated with early-onset periodontitis.
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ranking = 1
keywords = dental
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22/87. Oral and dental manifestations of vitamin d-dependent rickets type I: report of a pediatric case.

    vitamin d-dependent rickets type I (VDDRI) represents an autosomal recessive hereditary defect in vitamin d metabolism. patients with VDDRI have mutations of chromosome 12 that affect the gene for the enzyme 1-alpha-hydroxylase, resulting in decreased levels of 1,25(OH)(2) vitamin d. Clinical features include growth failure, hypotonia, weakness, rachitic rosary, convulsions, tetany, open fontanels, and pathologic fractures. The oral and dental manifestations of VDDRI have not been described. Here we present the case of a 10-year-old girl affected by VDDRI, as established by the combination of clinical and radiographic findings, family history, and laboratory values. Dental examination revealed markedly hypoplastic, yellowish-to-brownish enamel in all permanent teeth, malocclusion, and chronic periodontal disease. Large quadrangular pulp chambers and short roots were evident in dental radiographs. light microscopic and ultrastructural examination showed abnormalities of dental hard tissues, affecting both enamel and dentin. The differential diagnosis and treatment of VDDRI are discussed.
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ranking = 7
keywords = dental
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23/87. Peripheral inflammatory root resorption. A review of the literature with case reports.

    External resorptions associated with inflammation in marginal tissues are many times misdiagnosed and confused with caries and internal resorptions. A lack of uniformity in nomenclature has added to the confusion. This paper reviews the literature and presents cases to illustrate a rational approach to diagnosis and treatment. A new name is suggested to better reflect the features of this type of root resorption: peripheral inflammatory root resorption.
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ranking = 0.28060444513418
keywords = caries
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24/87. Late-onset Papillon-Lefevre syndrome without alteration of the cathepsin c gene.

    Mutations in the cathepsin c gene have recently been detected in Papillon-Lefevre syndrome (PLS). Until now, 5 cases with the late-onset variation of this disease have been reported in the literature. The genetic background of this type of PLS is still unknown. We describe a 46-year-old woman with late-onset transgredient palmar hyperkeratosis and a 10-year history of severe periodontal disease. histology of skin biopsy specimens revealed a psoriasiform pattern. Dental examination showed severe gingival inflammation with loss of alveolar bone. dental plaque investigated by a polymerase chain reaction method revealed dna signals of 5 different dental bacteria. dna from EDTA blood was investigated for mutations in the cathepsin c gene by polymerase chain reaction analysis and direct sequencing. A silent variation in the codon for proline-459 was detected but interpreted as a polymorphism of this gene. All genetic linkage and mutation studies for PLS performed so far have shown that PLS is genetically homogeneous. Our patient with late-onset variation of PLS, however, did not show a mutation in the cathepsin c gene. Thus, we suspect that there is another genetic cause for the late-onset forms of PLS.
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ranking = 1
keywords = dental
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25/87. Suppression of alveolar bone resorption by etidronate treatment for periodontal disease: 4- to 5-year follow-up of four patients.

    Four women with periodontitis received intermittent cyclical etidronate (etidronate administered orally at a dose of 200 mg/day for 2 weeks, at intervals of 10-12 weeks or 6 months) for 4-5 years in addition to ordinary dental therapy. Alveolar bone density was measured using a new method comparing the percentage increase in density. Mean alveolar bone density increased significantly during intermittent cyclical etidronate treatment. Significant reductions were observed in the mobility of the teeth and the depth of periodontal pockets. There were significant correlations between alveolar bone density and both mobility of the teeth and the depth of the alveolar pockets. It is concluded that increases in alveolar bone density are associated with the clinical benefits of etidronate in the treatment of periodontitis.
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ranking = 1
keywords = dental
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26/87. Decision analysis for periodontal therapy.

    Current decision-making approaches in clinical medicine and dentistry are based on principles developed when diagnostic and therapeutic options were few. The rapid pace of new technology development and the role of third-party payment systems are increasingly requiring that health-care providers and patients confront very complex decisions. These decisions typically involve significant uncertainty (e.g., How will a specific patient respond to each possible treatment?) and difficult tradeoffs (e.g., How much are patients willing to pay in money, time, and treatment effectiveness to avoid pain and discomfort?). This paper discusses high-quality decision-making. High-quality diagnostic and therapeutic decisions result from a well-developed decision basis that represents the alternatives, information, and preferences pertaining to the decision at hand. An effective decision basis is framed to address patients' and clinicians' key concerns. The resulting recommendation for action is based on an understanding of what factors are most sensitive in determining the best course of action. Moreover, the value of additional information-gathering efforts (e.g., further diagnosis) can be measured before the information is obtained to determine whether it is worth more than it costs. The paper illustrates the need for better decision-making methods with a sample patient case, discusses key decision analysis principles and methods, identifies specific areas where periodontal decision-making can be improved by decision analysis, and presents a periodontal decision analysis case. It then discusses how intelligent decision system technology can make decision analysis widely available in a clinical setting and concludes by exploring how a future dental office might use this technology on a routine basis.
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ranking = 1
keywords = dental
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27/87. Sickle cell disease and trait: an increase in trabecular spacing, a case study.

    A case report of a patient with sickle cell disease trait and the radiographically evident trabecular bone changes is examined in this article. The purpose of this article is to raise awareness in the dental and dental hygiene professional community of the treatment and clinical management of patients with sickle cell disease (SCD) and sickle cell disease trait (SCD trait). dentists and dental hygienists can provide optimum clinical care for this patient population by incorporating appropriate clinical management according to the most recent advances in the recognition and treatment of patients with SCD and SCD trait.
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ranking = 3
keywords = dental
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28/87. The healing potential of periodontal-endodontic lesions.

    Osseous lesions involving the periodontium, and which are sometimes associated with discomfort and pathologic changes such as swelling or the development of a sinus tract, are not always due to periodontal disease. Thus, it is not uncommon to find a dentition with generally good periodontal health but with one tooth having a severe isolated bony periodontal defect. In other cases, periodontal treatment may result in a general improvement, except in relation to one tooth which does not respond to the therapy. Very often these cases are instances of combined periodontal-endodontic lesions, but which are solely of pulpal origin. This paper serves to help the dental practitioner recognise the disease process underlying the condition and appreciate its effective management with non-surgical root canal treatment.
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ranking = 1
keywords = dental
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29/87. The down syndrome patient in dental practice, Part II: clinical considerations.

    down syndrome (DS), or trisomy 21, is a genetic disorder which results in intellectual impairment, typical craniofacial features and a wide spectrum of phenotypic abnormalities (reviewed by Kieser et al, 2003). Despite a large volume of research into this condition, its prevalence remains high (1 in 700 live births - Serra and Neri, 1990; Reeves, 2000). This, together with a notable increase in life expectancy (Pilcher, 1998), improved health care and a greater degree of integration into society in new zealand has resulted in an increased demand for dental care.
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ranking = 5
keywords = dental
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30/87. Unusual oral manifestations and evolution in glycogen storage disease type Ib.

    glycogen storage disease type Ib is a rare inherited metabolic disorder that is caused by a deficiency of glucose-6-phosphate translocase with consequent accumulation of glycogen. The purpose of this study is to report a case affected by glycogen storage disease type Ib in which unusual oral findings were evident and to review the pertinent literature. The disease presents with failure to thrive, hepatomegaly, hypoglycemia, hyperlacticacidemia, neutropenia, and neutrophilic dysfunction causing increased susceptibility to recurrent infections. Common intraoral manifestations are dental caries, gingivitis, periodontal disease, delayed dental maturation and eruption, oral bleeding diathesis, and oral ulcers. Conversely, unusual oral lesions were observed in this case as hyperplastic-hypertrophic gingiva and giant cell granulomatous epulis. The treatment with granulocyte colony-stimulating factor markedly increased the neutrophil counts and reduced the frequency of infections and inflammations. Proper evaluation of the patient's oral condition, a program of preventive measures, and suitable medical consultation are important to minimize and avoid long-term complications.
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ranking = 4.1941780657632
keywords = dental caries, dental, caries
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