1/5. Retinal periphlebitis in patients with acquired immunodeficiency syndrome with cytomegalovirus retinitis mimics acute frosted retinal periphlebitis.Acute frosted retinal periphlebitis is an inflammatory condition of unknown origin characterized by marked perivenular infiltration in otherwise healthy patients. We encountered seven patients with acquired immunodeficiency syndrome who exhibited visual loss associated with an unusual diffuse retinal periphlebitis very similar in appearance to acute frosted retinal periphlebitis. Each patient developed a thick inflammatory infiltrate surrounding the retinal venules, creating a frosted appearance. Two cases were bilateral. All patients had areas of more typical cytomegalovirus retinitis in their involved eye(s). Five of six patients treated with ganciclovir sodium showed improvement not only of the cytomegalovirus retinitis but also of the periphlebitis. Although we do not have histopathologic evidence that cytomegalovirus was the cause of these cases of periphlebitis, we believe that periphlebitis may be a previously unrecognized finding of cytomegalovirus retinitis in patients with acquired immunodeficiency syndrome. So far, there is no evidence implicating cytomegalovirus as the cause of acute frosted retinal periphlebitis in healthy patients.- - - - - - - - - - ranking = 1keywords = cytomegalovirus retinitis, retinitis, cytomegalovirus (Clic here for more details about this article) |
2/5. Acute frosted retinal periphlebitis associated with cytomegalovirus retinitis.The clinical picture of an acute frosted periphlebitis has been reported in a limited number of otherwise healthy patients, and in one case of human immunodeficiency virus (hiv) infection. The disease is usually bilateral and highly sensitive to steroids. The case of a 26-year-old, hiv-seropositive woman who developed unilateral diffuse perivenous sheathing in the course of recurrent cytomegalovirus retinitis is reported. The appearance of the retinovasculitis was identical to that described as an acute frosted periphlebitis, and the disease proved to be highly sensitive to a combined treatment of steroids and ganciclovir. The clinical findings in this case support the possibility that the appearance of an acute frosted periphlebitis can occur in response to several different stimuli, including cytomegalovirus.- - - - - - - - - - ranking = 0.71390936885925keywords = cytomegalovirus retinitis, retinitis, cytomegalovirus (Clic here for more details about this article) |
3/5. Retinal periphlebitis and retinal pigment epithelium changes associated with multiple sclerosis: a report of two cases.Two patients with definite MS and no significant visual loss are presented, because of the marked bilateral sheathing of retinal veins, and diffuse pigmentary changes in the first patient, and the previously unreported paravenous pigmentation with bone corpuscular configuration in the second patient. The lesions in the second patient are similar to paravenous retinitis pigmentosa. We assume that the RPE lesions may be secondary to perivasculitis, which is not uncommonly seen in MS patients.- - - - - - - - - - ranking = 0.0016084296211138keywords = retinitis (Clic here for more details about this article) |
4/5. Retinal periphlebitis as the initial clinical finding in a patient with Hodgkin's disease.A 28-year-old woman noted decreased vision in one eye and was found to have bilateral optic disc swelling, periphlebitis, focal chorioretinitis, and vitritis. Subsequent lymph node biopsy revealed nodular sclerosing. Hodgkin's disease, stage II-A. The ocular manifestations of the disease resolved in response to systemic radiation therapy. The relationship of the ophthalmic findings to the systemic disease are discussed.- - - - - - - - - - ranking = 0.0016084296211138keywords = retinitis (Clic here for more details about this article) |
5/5. Frosted retinal periphlebitis in the acquired immunodeficiency syndrome.Six patients with the acquired immunodeficiency syndrome had frosted periphlebitis associated with large areas of cytomegalovirus retinitis. Following the administration of ganciclovir, periphlebitis resolved within 2-6 weeks concomitant with quieting of cytomegalovirus retinitis. Frosted retinal periphlebitis in the acquired immunodeficiency syndrome is associated with cytomegalovirus retinitis in north america. Medical treatment of cytomegalovirus retinitis leads to resolution of the periphlebitis without the need for systemic corticosteroids.- - - - - - - - - - ranking = 0.43030530666803keywords = cytomegalovirus retinitis, retinitis, cytomegalovirus (Clic here for more details about this article) |