Cases reported "Phlebitis"

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1/17. Symptomatic combined homozygous factor xii deficiency and heterozygous factor v Leiden. [email protected]

    A family with a combined deficiency of factor XII and factor v Leiden is presented. The proposita is a 72-year-old who showed a mild to moderate thrombotic tendency characterized by two episodes of deep venous thrombosis and superficial phlebitis between the age of 50 and 71. She was shown to be carrier of homozygous factor xii deficiency and heterozygous FV Leiden mutation. A sister of the proposita showed the same pattern but remained asymptomatic. Other family members showed either isolated heterozygous factor xii deficiency or combined heterozygous factor xii deficiency and heterozygous FV Leiden mutation but were all asymptomatic. These data lend support to those who maintain that FV Leiden is a mild genetic determinant for thrombosis. The role of FXII deficiency as an additional risk factor remains questionable.
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ranking = 1
keywords = thrombosis, venous thrombosis, deep
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2/17. Endophlebitis of the leg caused by brucella infection.

    brucellosis is hyperendemic in saudi arabia where, despite rapid urbanisation, a large segment of the population has a nomadic background and clings to cultural traditions such as the drinking of raw milk. We report here an unusual complication of brucellosis in a microbiology technologist. A 41-year-old male presented with an 8-day history of right ankle pain which, over a 3-day period, extended up to his calf where swelling and tightness developed. The leg symptomatology occurred on a background of fever, seats and rigors. X-ray of the limb was normal but a venogram revealed thrombosis of the deep veins of the right calf. Although his blood culture was negative, he developed high brucella antibody titres. Treatment with anticoagulants combined with a course of doxycycline and rifampin produced a full recovery.
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ranking = 0.47272496836966
keywords = thrombosis, deep
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3/17. Chronic intestinal lymphocytic microphlebitis.

    The authors report two cases of a peculiar microphlebitis of the intestines, similar to that described by Saraga and Costa quite recently [5]. The patients had undergone hemicolectomy because of evolving ileus caused by cecal polyps or lipohyperplasia, respectively. Pseudomembranous-ulcerative inflammation of the cecum and variously intense lymphocytic infiltrates of numerous small submucosal veins and venules of the intestines were found in both cases. Thrombosis occurred very rarely in the affected vessels, although sometimes it was found in deeper and larger veins. arteries, lymphatics, mesenterial veins and lymph nodes were normal. Parts of the distal ileum and ascending colon displayed the phlebitic changes without mucosal alterations. The authors hypothesize that it was not the abnormal local circulation, but some hitherto not fully clarified immunological disorder that resulted in the disease. In contrast to the claim of Saraga and Costa [5], it is suggested that thrombosis of the small veins does not have a significant role in the development of the lesions, but a complex process that includes the entry of antigens via the altered mucosa followed by an immunogenic inflammatory response of the small veins is responsible for the pathogenesis.
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ranking = 0.47272496836966
keywords = thrombosis, deep
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4/17. panuveitis associated with multiple sclerosis complicated by cerebral venous thrombosis.

    PURPOSE: To report cerebral venous thrombosis as a complication of intravenous corticosteroid treatment in a patient with multiple sclerosis. METHOD: A case report. A 44-year-old woman with a previous diagnosis of multiple sclerosis presented with panuveitis and retinal perivasculitis. Intravenous pulse corticosteroid therapy was given for three days. RESULTS: The panuveitis and retinal periphlebitis began to resolve within one week; however, ten days after the last corticosteroid dose, the patient was hospitalized with the diagnosis of cerebral venous thrombosis. CONCLUSION: Although intravenous corticosteroid treatment for uveitis associated with multiple sclerosis can be very helpful, the patient should be monitored closely for systemic side effects.
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ranking = 3.163650189782
keywords = thrombosis, venous thrombosis
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5/17. Posttraumatic phlegmasia cerulea dolens: an indication for the Greenfield filter.

    Phlegmasia cerulea dolens (PCD) can be a threat to both life and limb and therefore must receive prompt treatment. In most clinical settings, anticoagulant therapy is standard treatment for PCD. Iliofemoral thrombectomy has been recommended as surgical treatment of massive thrombosis where venous gangrene may occur. In the severely traumatized patient, however, massive venous occlusion presents difficulties in management in a complex clinical setting. We have described a 52-year-old white man who had a posterior fracture dislocation of the right hip, with a pulseless, cyanotic, swollen right leg. A Greenfield filter was placed via the internal jugular vein approach, followed by leg and thigh fasciotomy and iliofemoral thrombectomy. Femoral arteriotomy revealed good inflow, and arterial thrombectomy yielded very little thrombus. He subsequently required an above-knee amputation for venous gangrene. In cases of PCD, iliofemoral thrombectomy should be considered early when the threat of venous gangrene exists. We propose internal jugular vein placement of a Greenfield filter before venous thrombectomy. The Greenfield filter has proven to be a safe and effective prophylaxis for thromboembolism should a clot migrate or detach during thrombectomy. Additionally, placement of the filter in the early post-traumatic period would safeguard against pulmonary emboli during a period in which anti-coagulant therapy would be contraindicated.
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ranking = 0.47243315968582
keywords = thrombosis
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6/17. Intrathoracic extravasation of sclerosing agents associated with central venous catheters.

    Two children receiving continuous infusions of vesicant chemotherapy through central venous catheters (CVCs) developed venous thrombosis, and intrathoracic extravasations ensued. One child receiving a continuous vincristine infusion presented with signs of thoracic venous obstruction, fever, and respiratory distress and had pleural effusions and pulmonary infiltrates on his chest roentgenogram. The other child was receiving a continuous doxorubicin infusion and developed superior vena cava thrombosis and retrograde extravasation along the catheter tunnel site. Both children improved after chemotherapy was discontinued and the CVCs removed. Catheter placement and the continuous infusion of sclerosing agents are discussed.
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ranking = 0.99970819131616
keywords = thrombosis, venous thrombosis
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7/17. CT demonstration of calcified post-thrombotic inferior vena cava.

    A calcified thrombus in the inferior vena cava is imaged and exactly located by computed tomography in an adult presenting with acute phlebitis complicating deep venous thrombosis. It is the purpose of this case report to discuss the rare finding of inferior vena caval (IVC) calcification and to demonstrate the computed tomographic (CT) findings of a calcified post-thrombotic inferior vena cava.
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ranking = 0.52756684031418
keywords = thrombosis, venous thrombosis, deep
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8/17. Drifting hematomas.

    When blood is released into the tissues of the lower extremities, it may drift downward under the influence of the force of gravity to produce the influence of the force of gravity to produce pain, edema, redness and heat. A crescent shaped ecchymosis may appear around the malleoli. The relationship between cause and effect may be obscured by a time interval of up to four weeks before conclusive signs are seen. Early differentiation of this condition from that of phlebitis and deep venous thrombosis is necessary. Such differentiation prevents inappropriate and potentially dangerous anticoagulation as well as the disastrous consequences of untreated edema of the legs. With prompt, appropriate treatment, complete recovery can be expected. If treatment is delayed, permanent damage to the leg can result.
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ranking = 0.52756684031418
keywords = thrombosis, venous thrombosis, deep
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9/17. Complications of heparin-induced thrombocytopenia.

    Four cases are presented which are believed to represent thrombocytopenia associated with intravascular thrombosis and vascular occlusion in patients receiving heparin. patients with gangrene all had pre-existing arterial disease and arterial insufficiency. Such venous and arterial thromboses are paradoxic and unpredictable and are completely against the goal of therapy. These complications may have been prevented if the developing thrombocytopenia was discovered earlier and heparin discontinued. Three of these patients died as a result of their complications, and one had an amputation. The unpredictable pattern of such paradoxic reactions requires close monitoring of the platelet count as well as activated PTT and prothrombin time.
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ranking = 0.47243315968582
keywords = thrombosis
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10/17. Ultrasonographic diagnosis of incomplete inferior vena caval thrombosis secondary to periphlebitis: the importance of a complete survey examination.

    A case of unsuspected, asymptomatic, partial thrombotic occlusion of the inferior vena cava secondary to endometritis and periphlebitis is presented. The diagnostic findings of this entity are described, and the importance of a complete abdominal survey, especially in the septic patient, is emphasized. Real-time sector scanning greatly facilitates the performance of this survey.
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ranking = 1.8897326387433
keywords = thrombosis
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