Cases reported "Plague"

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1/12. Cases of cat-associated human plague in the Western US, 1977-1998.

    Exposure to cats infected with yersinia pestis is a recently recognized risk for human plague in the US. Twenty-three cases of cat-associated human plague (5 of which were fatal) occurred in 8 western states from 1977 through 1998, which represent 7.7% of the total 297 cases reported in that period. Bites, scratches, or other contact with infectious materials while handling infected cats resulted in 17 cases of bubonic plague, 1 case of primary septicemic plague, and 5 cases of primary pneumonic plague. The 5 fatal cases were associated with misdiagnosis or delays in seeking treatment, which resulted in overwhelming infection and various manifestations of the systemic inflammatory response syndrome. Unlike infections acquired by flea bites, the occurrence of cat-associated human plague did not increase significantly during summer months. plague epizootics in rodents also were observed less frequently at exposure sites for cases of cat-associated human plague than at exposure sites for other cases. The risk of cat-associated human plague is likely to increase as residential development continues in areas where plague foci exist in the western US. Enhanced awareness is needed for prompt diagnosis and treatment.
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2/12. plague and the gallium scan: Case report.

    inflammation in the right axillary lymph nodes and the meninges was detected by 67Gacitrate scans in an 11-year-old boy with yersinia pestis infection. This case provides another example of 67Ga localizing to areas of infection, indicating potential utility in future cases of bubonic plague.
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3/12. Cat bite transmission of yersinia pestis infection to man.

    The transmission of bubonic plague from the kitten of a domestic cat to a man by means of a bite on a finger is described. The human case was complicated by the development of a secondary meningitis, followed, after specific therapy, by protracted recovery. The kitten showed swollen lymph nodes of the head and neck, frothing at the mouth and nostrils, and signs of an acute infectious disease which had a fatal termination. yersinia pestis was isolated on about the 8th day from the cerebrospinal fluid of the man. The foster mother of the kitten exhibited signs of spinal and cerebral meningitis but recovered following treatment; her serum contained plague antibody levels of 1:512 and 1:1024 on the 22nd and 34th days respectively after the first evidence of illness. Three litter mates of the kitten also died. The outbreak occurred on a farm in the Graaff-Reinet district of the eastern Cape Province, which is situated about 160 km from the nearest known natural plague focus.
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4/12. Imported plague--new york city, 2002.

    On November 1, 2002, a married couple traveled from Santa Fe County, new mexico, to new york city (NYC), where they both became ill with fever and unilateral inguinal adenopathy; bubonic plague (yersinia pestis) was diagnosed subsequently. This report summarizes the clinical and public health investigation of these cases and underscores the importance of rapid diagnosis and communication among health-care providers, public health agencies, and the public when patients seek medical attention for an illness that might be caused by an agent of terrorism.
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5/12. Clinical and pathologic differential diagnosis of selected potential bioterrorism agents of interest to pediatric health care providers.

    The early recognition of potential bioterrorism agents has been of increasing concern in recent years. The Centers for Disease Control and Prevention has categorized and listed biological terrorism agents. Although any or all of the highest risk biological agents (including inhalation anthrax, pneumonic plague, smallpox, tularemia, botulism, and viral hemorrhagic fevers) can be seen in the pediatric patient, several agents might closely resemble--at least in their initial stages-some of the more common childhood illnesses. The awareness of these similarities and, more importantly,their differences, are critical for all health care professionals. Selected examples of some typical childhood illnesses are presented and then compared with three of the most virulent biological agents (smallpox, anthrax and plague) that might be used in a bioterrorism attack.
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6/12. Human bubonic plague transmitted by a domestic cat scratch.

    Bubonic plague was transmitted to a 10-year-old girl in oregon by a scratch wound inflicted by a domestic cat. The cat probably was infected by contact with infected wild rodents or their fleas. yersinia pestis was identified in Diamanus montanus fleas collected from an abandoned burrow near the patient's home. Domestic cats may infect humans with Y pestis by inoculation from a scratch.
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7/12. The hemorrhagic fevers of Southern africa with special reference to studies in the South African Institute for Medical research.

    In this review of studies on the hemorrhagic fevers of Southern africa carried out in the South African Institute for Medical research, attention has been called to occurrence of meningococcal septicemia in recruits to the mining industry and South African Army, to cases of staphylococcal and streptococcal septicemia with hemorrhagic manifestations, and to the occurrence of plague which, in its septicemic form, may cause a hemorrhagic state. "Onyalai," a bleeding disease in tropical africa, often fatal, was related to profound thrombocytopenia possibly following administration of toxic witch doctor medicine. Spirochetal diseases, and rickettsial diseases in their severe forms, are often manifested with hemorrhagic complications. Of enterovirus infections, Coxsackie B viruses occasionally caused severe hepatitis associated with bleeding, especially in newborn babies. Cases of hemorrhagic fever presenting in February-March, 1975 are described. The first outbreak was due to marburg virus disease and the second, which included seven fatal cases, was caused by rift valley fever virus. In recent cases of hemorrhagic fever a variety of infective organisms have been incriminated including bacterial infections, rickettsial diseases, and virus diseases, including Herpesvirus hominis; in one patient, the hemorrhagic state was related to rubella. A boy who died in a hemorrhagic state was found to have congo fever; another patient who died of severe bleeding from the lungs was infected with leptospira canicola, and two patients who developed a hemorrhagic state after a safari trip in Northern botswana were infected with trypanosoma rhodesiense. An illness manifested by high fever and melena developed in a young man after a visit to zimbabwe; the patient was found to have both malaria and marburg virus disease.
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8/12. plague in a neonate.

    More than half of the cases of plague in the united states are diagnosed in children. In the 1970s, 105 cases were reported, a 350% increase over the 1960s. plague should be considered in the differential diagnosis of children from the western united states who have sepsis, especially those with lymphadenopathy. Complications of plague include meningitis, metabolic encephalopathy, abscess, and pneumonia. With appropriate treatment, prompt clinical response usually occurs. Careful isolation and epidemiologic investigation are essential to prevent the spread of the disease.
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9/12. Feline plague in new mexico: report of five cases.

    Naturally acquired plague was diagnosed in 5 domestic cats. The cats apparently contracted the disease through contact with sylvatic rodents or their fleas in plague-enzootic areas. The diagnosis was confirmed by direct immunofluorescence and isolation of yersinia pestis on culture of abscess material. abscess formation, lymphadenitis, lethargy, and fever were consistent clinical findings.
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10/12. Cat-transmitted fatal pneumonic plague in a person who traveled from colorado to arizona.

    plague, primarily a disease of rodents and their infected fleas, is fatal in 50% of infected humans if untreated. In the united states, human cases have been concentrated in the southwest. The most common modes of plague transmission are through flea bites or through contact with infected blood or tissues; however, primary pneumonic plague acquired from cats has become increasingly recognized. We report on the case investigation of a patient, presumably exposed to a plague-infected cat in colorado, who presented with gastrointestinal symptoms, and subsequently died of primary pneumonic plague. public health officials should be vigilant for plague activity in rodent populations, veterinarians should suspect feline plague in ill or deceased cats, and physicians should have a high index of suspicion for plague in any person who has traveled to plague enzootic areas.
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